An effective vaginal gel to deliver CRISPR/Cas9 system encapsulated in poly (β-amino ester) nanoparticles for vaginal gene therapy

by Gang Niu, Zhuang Jin, Chong Zhang, Dan He, Xueqin Gao, Chenming Zou, Wei Zhang, Jiahui Ding, Bhudev C. Das, Konstantin Severinov, Inga Isabel Hitzeroth, Priya Ranjan Debata, Xin Ma, Xun Tian, Qinglei Gao, Jun Wu, Zeshan You, Rui Tian, Zifeng Cui, Weiwen Fan, Weiling Xie, Zhaoyue Huang, Chen Cao, Wei Xu, Hongxian Xie, Hongyan Xu, Xiongzhi Tang, Yan Wang, Zhiying Yu, Hui Han, Songwei Tan, Shuqin Chen, Zheng Hu
Published 2020-08-01

The utility of a methylation panel in the assessment of clinical response to radiofrequency ablation for Barrett's esophagus

by Wladyslaw Januszewicz, Vinod V. Subhash, William Waldock, Daniel I. Fernando, Giorgio Bartalucci, Hamza Chettouh, Ahmad Miremadi, Maria O'Donovan, Rebecca C. Fitzgerald, Massimiliano di Pietro
Published 2020-08-01

New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses

by Alice Gutjahr, Laura Papagno, Fabienne Vernejoul, Thierry Lioux, Fabienne Jospin, Blandine Chanut, Eric Perouzel, Nicolas Rochereau, Victor Appay, Bernard Verrier, Stéphane Paul
Published 2020-08-01

Chronic myelomonocytic leukaemia stem cell transcriptomes anticipate disease morphology and outcome

by Daniel H Wiseman, Syed M Baker, Arundhati V Dongre, Kristian Gurashi, Joanna A Storer, Tim CP Somervaille, Kiran Batta
Published 2020-08-01

VLDL-specific increases of fatty acids in autism spectrum disorder correlate with social interaction

by Noriyoshi Usui, Keiko Iwata, Taishi Miyachi, Shu Takagai, Keisuke Wakusawa, Takahiro Nara, Kenji J. Tsuchiya, Kaori Matsumoto, Daisuke Kurita, Yosuke Kameno, Tomoyasu Wakuda, Kiyokazu Takebayashi, Yasuhide Iwata, Toru Fujioka, Takaharu Hirai, Manabu Toyoshima, Tetsuo Ohnishi, Tomoko Toyota, Motoko Maekawa, Takeo Yoshikawa, Masato Maekawa, Kazuhiko Nakamura, Masatsugu Tsujii, Toshiro Sugiyama, Norio Mori, Hideo Matsuzaki
Published 2020-08-01

Dissociations in cortical thickness and surface area in non-comorbid never-treated patients with social anxiety disorder

by Xun Zhang, Qiang Luo, Song Wang, Lihua Qiu, Nanfang Pan, Weihong Kuang, Su Lui, Xiaoqi Huang, Xun Yang, Graham J. Kemp, Qiyong Gong
Published 2020-08-01

Children first, or last?

by Neena Modi
Published 2020-06-01

A novel rabies vaccine based on infectious propagating particles derived from hybrid VEEV-Rabies replicon

by Ya-Nan Zhang, Chen Chen, Cheng-Lin Deng, Cheng-guang Zhang, Na Li, Zhen Wang, Ling Zhao, Bo Zhang
Published 2020-06-01

Cell motility and migration as determinants of stem cell efficacy

by Lusine Danielyan, Matthias Schwab, Georg Siegel, Bianca Brawek, Olga Garaschuk, Nithi Asavapanumas, Marine Buadze, Ali Lourhmati, Hans-Peter Wendel, Meltem Avci-Adali, Marcel A. Krueger, Carsten Calaminus, Ulrike Naumann, Stefan Winter, Elke Schaeffeler, Annett Spogis, Sandra Beer-Hammer, Jonas J. Neher, Gabriele Spohn, Anja Kretschmer, Eva-Maria Krämer-Albers, Kerstin Barth, Hong Jun Lee, Seung U. Kim, William H. Frey, II, Claus D. Claussen, Dirk M. Hermann, Thorsten R. Doeppner, Erhard Seifried, Christoph H. Gleiter, Hinnak Northoff, Richard Schäfer
Published 2020-10-01

Overcoming gaps in the treatment of neurodegenerative disease

Published 2020-10-01

Increased migratory and homing abilities of neural and mesenchymal stem cell populations by transient cell modifications: Preclinical progress and clinical relevance

by Johannes Boltze, Nadine Didwischus, Shen Li, Jukka Jolkkonen, Akihiko Taguchi
Published 2020-10-01

Dengue and Zika virus infections are enhanced by live attenuated dengue vaccine but not by recombinant DSV4 vaccine candidate in mouse models

by Rahul Shukla, Hemalatha Beesetti, Julia A. Brown, Richa Ahuja, Viswanathan Ramasamy, Rajgokul K. Shanmugam, Ankur Poddar, Gaurav Batra, Florian Krammer, Jean K. Lim, Sachin Kale, Altaf A. Lal, Sathyamangalam Swaminathan, Navin Khanna
Published 2020-10-01

Ex-vivo delivery of monoclonal antibody (Rituximab) to treat human donor lungs prior to transplantation

by Terrance J.Y. Ku, Rafaela V.P. Ribeiro, Victor H. Ferreira, Marcos Galasso, Shaf Keshavjee, Deepali Kumar, Marcelo Cypel, Atul Humar
Published 2020-10-01

Taking a SPOP at renal cell carcinoma – unraveling a novel pathway for Tumor progression in clear cell RCC

by Hiren V. Patel, Sai K. Doppalapudi, Eric A. Singer
Published 2020-06-01

Clinical implications of serum neurofilament in newly diagnosed MS patients: A longitudinal multicentre cohort study

by Stefan Bittner, Falk Steffen, Timo Uphaus, Muthuraman Muthuraman, Vinzenz Fleischer, Anke Salmen, Felix Luessi, Achim Berthele, Luisa Klotz, Sven G. Meuth, Antonios Bayas, Friedemann Paul, Hans-Peter Hartung, Ralf Linker, Christoph Heesen, Martin Stangel, Brigitte Wildemann, Florian Then Bergh, Björn Tackenberg, Tania Kuempfel, Frank Weber, Uwe K. Zettl, Ulf Ziemann, Hayrettin Tumani, Sergiu Groppa, Mark Mühlau, Carsten Lukas, Bernhard Hemmer, Heinz Wiendl, Ralf Gold, Frauke Zipp
Published 2020-06-01

Blood biomarkers on admission in acute traumatic brain injury: Relations to severity, CT findings and care path in the CENTER-TBI study

by Endre Czeiter, Krisztina Amrein, Benjamin Y. Gravesteijn, Fiona Lecky, David K. Menon, Stefania Mondello, Virginia F.J. Newcombe, Sophie Richter, Ewout W. Steyerberg, Thijs Vande Vyvere, Jan Verheyden, Haiyan Xu, Zhihui Yang, Andrew I.R. Maas, Kevin K.W. Wang, András Büki
Published 2020-06-01

5th Festival of genomics, 29th – 30th January 2020, London UK

by Hannah K Ralph
Published 2020-06-01

Symphony in chaos: Immune orchestra during pancreatic cancer progression

by Prateek Sharma, Tejeshwar Jain, Vrishketan Sethi, Vikas Dudeja
Published 2020-06-01

Lung immunoglobulin A immunity dysregulation in cystic fibrosis

by Amandine M. Collin, Marylène Lecocq, Sabrina Noel, Bruno Detry, François M. Carlier, Frank Aboubakar Nana, Caroline Bouzin, Teresinha Leal, Marjorie Vermeersch, Virginia De Rose, Lucile Regard, Clémence Martin, Pierre-Régis Burgel, Delphine Hoton, Stijn Verleden, Antoine Froidure, Charles Pilette, Sophie Gohy
Published 2020-10-01

SP6616 as a Kv2.1 inhibitor efficiently ameliorates peripheral neuropathy in diabetic mice

by Xialin Zhu, Yun Chen, Xu Xu, Xiaoju Xu, Yin Lu, Xi Huang, Jinpei Zhou, Lihong Hu, Jiaying Wang, Xu Shen
Published 2020-11-01