Targeting and Efficacy of Novel mAb806-Antibody-Drug Conjugates in Malignant Mesothelioma

by Puey-Ling Chia, Sagun Parakh, Ming-Sound Tsao, Nhu-An Pham, Hui K. Gan, Diana Cao, Ingrid J. G. Burvenich, Angela Rigopoulos, Edward B. Reilly, Thomas John, Andrew M. Scott
Published 2020-10-01

Co-overexpression of Met and Hepatocyte Growth Factor Promotes Systemic Metastasis in NCI-H460 Non-Small Cell Lung Carcinoma Cells

by Roya Navab, Jiang Liu, Isolde Seiden-Long, Warren Shih, Ming Li, Bizhan Bandarchi, Yan Chen, Davina Lau, Yen-Fen Zu, Dave Cescon, Chang Qi Zhu, Shawna Organ, Emin Ibrahimov, Dina Ohanessian, Ming-Sound Tsao
Published 2009-12-01

Molecular testing and treatment patterns for patients with advanced non-small cell lung cancer: PIvOTAL observational study.

by Dae Ho Lee, Ming-Sound Tsao, Karl-Otto Kambartel, Hiroshi Isobe, Ming-Shyan Huang, Carlos H Barrios, Adnan Khattak, Filippo de Marinis, Smita Kothari, Ashwini Arunachalam, Xiting Cao, Thomas Burke, Amparo Valladares, Javier de Castro
Published 2018-01-01

Somatic Alteration Burden Involving Non-Cancer Genes Predicts Prognosis in Early-Stage Non-Small Cell Lung Cancer

by Dennis Wang, Nhu-An Pham, Timothy M. Freeman, Vibha Raghavan, Roya Navab, Jonathan Chang, Chang-Qi Zhu, Dalam Ly, Jiefei Tong, Bradly G. Wouters, Melania Pintilie, Michael F. Moran, Geoffrey Liu, Frances A. Shepherd, Ming-Sound Tsao
Published 2019-07-01

SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis.

by Bo Ram Kim, Emily Van de Laar, Michael Cabanero, Shintaro Tarumi, Stefan Hasenoeder, Dennis Wang, Carl Virtanen, Takaya Suzuki, Bizhan Bandarchi, Shingo Sakashita, Nhu An Pham, Sharon Lee, Shaf Keshavjee, Thomas K Waddell, Ming-Sound Tsao, Nadeem Moghal
Published 2016-11-01

Computer-assisted image analysis of the tumor microenvironment on an oral tongue squamous cell carcinoma tissue microarray

by Sangjune Laurence Lee, Michael Cabanero, Martin Hyrcza, Marcus Butler, Fei-Fei Liu, Aaron Hansen, Shao Hui Huang, Ming-Sound Tsao, Yuyao Song, Lin Lu, Wei Xu, Douglas B. Chepeha, David P. Goldstein, Ilan Weinreb, Scott V. Bratman
Published 2019-07-01

Chronic obstructive pulmonary disease prevalence and prediction in a high-risk lung cancer screening population

by John R. Goffin, Gregory R. Pond, Serge Puksa, Alain Tremblay, Michael Johnston, Glen Goss, Garth Nicholas, Simon Martel, Rick Bhatia, Geoffrey Liu, Heidi Schmidt, Sukhinder Atkar-Khattra, Annette McWilliams, Ming-Sound Tsao, Martin C. Tammemagi, Stephen Lam
Published 2020-11-01

Canadian Consensus for Biomarker Testing and Treatment of TRK Fusion Cancer in Adults

by D. Gwyn Bebb, Shantanu Banerji, Normand Blais, Patrice Desmeules, Sharlene Gill, Andrea Grin, Harriet Feilotter, Aaron R. Hansen, Martin Hyrcza, Monika Krzyzanowska, Barbara Melosky, Jonathan Noujaim, Bibiana Purgina, Dean Ruether, Christine E. Simmons, Denis Soulieres, Emina Emilia Torlakovic, Ming-Sound Tsao
Published 2021-01-01

The role of Cancer-Testis antigens as predictive and prognostic markers in non-small cell lung cancer.

by Thomas John, Maud H W Starmans, Yao-Tseng Chen, Prudence A Russell, Stephen A Barnett, Shane C White, Paul L Mitchell, Marzena Walkiewicz, Arun Azad, Philippe Lambin, Ming-Sound Tsao, Siddhartha Deb, Nasser Altorki, Gavin Wright, Simon Knight, Paul C Boutros, Jonathan S Cebon
Published 2013-01-01

Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non–Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion

by Jing Hao, Cédric Zeltz, Melania Pintilie, Quan Li, Shingo Sakashita, Tao Wang, Michael Cabanero, Sebastiao N. Martins-Filho, Dennis Y. Wang, Elena Pasko, Kalpana Venkat, Joella Joseph, Vibha Raghavan, Chang-Qi Zhu, Yu-Hui Wang, Nadeem Moghal, Ming-Sound Tsao, Roya Navab
Published 2019-05-01

Omega-3 Fatty Acids Prevent Early Pancreatic Carcinogenesis via Repression of the AKT Pathway

by Yongzeng Ding, Bhargava Mullapudi, Carolina Torres, Emman Mascariñas, Georgina Mancinelli, Andrew M. Diaz, Ronald McKinney, Morgan Barron, Michelle Schultz, Michael Heiferman, Mireille Wojtanek, Kevin Adrian, Brian DeCant, Sambasiva Rao, Michel Ouellette, Ming-Sound Tsao, David J. Bentrem, Paul J. Grippo
Published 2018-09-01

Cancer proteome and metabolite changes linked to SHMT2.

by Jiefei Tong, Jonathan R Krieger, Paul Taylor, Rick Bagshaw, Jae Kang, Swathi Jeedigunta, Leanne E Wybenga-Groot, Wen Zhang, Heba Badr, Shideh Mirhadi, Nhu-An Pham, Étienne Coyaud, Man Yu, Ming Li, Michael Cabanero, Brian Raught, Jason T Maynes, Cynthia Hawkins, Ming Sound Tsao, Michael F Moran
Published 2020-01-01

Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer.

by Deena M A Gendoo, Robert E Denroche, Amy Zhang, Nikolina Radulovich, Gun Ho Jang, Mathieu Lemire, Sandra Fischer, Dianne Chadwick, Ilinca M Lungu, Emin Ibrahimov, Ping-Jiang Cao, Lincoln D Stein, Julie M Wilson, John M S Bartlett, Ming-Sound Tsao, Neesha Dhani, David Hedley, Steven Gallinger, Benjamin Haibe-Kains
Published 2019-01-01

Cancer proteome and metabolite changes linked to SHMT2

by Jiefei Tong, Jonathan R. Krieger, Paul Taylor, Rick Bagshaw, Jae Kang, Swathi Jeedigunta, Leanne E. Wybenga-Groot, Wen Zhang, Heba Badr, Shideh Mirhadi, Nhu-An Pham, Étienne Coyaud, Man Yu, Ming Li, Michael Cabanero, Brian Raught, Jason T. Maynes, Cynthia Hawkins, Ming Sound Tsao, Michael F. Moran, Irina V. Lebedeva
Published 2020-01-01

Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation

by Yoshihito Kano, Teklab Gebregiworgis, Christopher B. Marshall, Nikolina Radulovich, Betty P. K. Poon, Jonathan St-Germain, Jonathan D. Cook, Ivette Valencia-Sama, Benjamin M. M. Grant, Silvia Gabriela Herrera, Jinmin Miao, Brian Raught, Meredith S. Irwin, Jeffrey E. Lee, Jen Jen Yeh, Zhong-Yin Zhang, Ming-Sound Tsao, Mitsuhiko Ikura, Michael Ohh
Published 2019-01-01

Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma.

by William W Lockwood, Raj Chari, Bradley P Coe, Kelsie L Thu, Cathie Garnis, Chad A Malloff, Jennifer Campbell, Ariane C Williams, Dorothy Hwang, Chang-Qi Zhu, Timon P H Buys, John Yee, John C English, Calum Macaulay, Ming-Sound Tsao, Adi F Gazdar, John D Minna, Stephen Lam, Wan L Lam
Published 2010-07-01

Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development.

by William W Lockwood, Ian M Wilson, Bradley P Coe, Raj Chari, Larissa A Pikor, Kelsie L Thu, Luisa M Solis, Maria I Nunez, Carmen Behrens, John Yee, John English, Nevin Murray, Ming-Sound Tsao, John D Minna, Adi F Gazdar, Ignacio I Wistuba, Calum E MacAulay, Stephen Lam, Wan L Lam
Published 2012-01-01

Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers.

by Lorin Dodbiba, Jennifer Teichman, Andrew Fleet, Henry Thai, Maud H W Starmans, Roya Navab, Zhuo Chen, Hala Girgis, Lawson Eng, Osvaldo Espin-Garcia, Xiaowei Shen, Bizhan Bandarchi, Joerg Schwock, Ming-Sound Tsao, Hala El-Zimaity, Sandy D Der, Wei Xu, Robert G Bristow, Gail E Darling, Paul C Boutros, Laurie E Ailles, Geoffrey Liu
Published 2015-01-01

Patient-derived tumor xenograft and organoid models established from resected pancreatic, duodenal and biliary cancers

by Nhu-An Pham, Nikolina Radulovich, Emin Ibrahimov, Sebastiao N. Martins-Filho, Quan Li, Melania Pintilie, Jessica Weiss, Vibha Raghavan, Michael Cabanero, Robert E. Denroche, Julie M. Wilson, Cristiane Metran-Nascente, Ayelet Borgida, Shawn Hutchinson, Anna Dodd, Michael Begora, Dianne Chadwick, Stefano Serra, Jennifer J. Knox, Steven Gallinger, David W. Hedley, Lakshmi Muthuswamy, Ming-Sound Tsao
Published 2021-05-01

Prediction of lung cancer risk at follow-up screening with low-dose CT: a training and validation study of a deep learning method

by Peng Huang, PhD, Cheng T Lin, MD, Yuliang Li, MS, Martin C Tammemagi, ProfPhD, Malcolm V Brock, ProfMD, Sukhinder Atkar-Khattra, BSc, Yanxun Xu, PhD, Ping Hu, ScD, John R Mayo, ProfMD, Heidi Schmidt, ProfMD, Michel Gingras, MD, Sergio Pasian, MD, Lori Stewart, MD, Scott Tsai, MD, Jean M Seely, MD, Daria Manos, MD, Paul Burrowes, MD, Rick Bhatia, MD, Ming-Sound Tsao, ProfMD, Stephen Lam, ProfMD
Published 2019-11-01