The Evolution and Prognostic Role of Tumour-Infiltrating Lymphocytes and Peripheral Blood-Based Biomarkers in Inflammatory Breast Cancer Patients Treated with Neoadjuvant Chemother...

by Christophe Van Berckelaer, Iris Vermeiren, Leonie Vercauteren, Charlotte Rypens, Gizem Oner, Xuan Bich Trinh, Wiebren A. A. Tjalma, Glenn Broeckx, Emmanuelle Charafe-Jauffret, Steven Van Laere, François Bertucci, Cecile Colpaert, Peter A. van Dam
Published 2021-09-01

Single-word comprehension deficits in the nonfluent variant of primary progressive aphasia

by Jolien Schaeverbeke, Silvy Gabel, Karen Meersmans, Rose Bruffaerts, Antonietta Gabriella Liuzzi, Charlotte Evenepoel, Eva Dries, Karen Van Bouwel, Anne Sieben, Yolande Pijnenburg, Ronald Peeters, Guy Bormans, Koen Van Laere, Michel Koole, Patrick Dupont, Rik Vandenberghe
Published 2018-07-01

Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer

by Jonas Steenbrugge, Jonas Steenbrugge, Jonas Steenbrugge, Niels Vander Elst, Kristel Demeyere, Olivier De Wever, Olivier De Wever, Niek N. Sanders, Niek N. Sanders, Wim Van Den Broeck, Luc Dirix, Steven Van Laere, Evelyne Meyer, Evelyne Meyer
Published 2019-12-01

Bioluminescence imaging of stroke-induced endogenous neural stem cell response

by Caroline Vandeputte, Veerle Reumers, Sarah-Ann Aelvoet, Irina Thiry, Sylvie De Swaef, Chris Van den Haute, Jesus Pascual-Brazo, Tracy D. Farr, Greetje Vande Velde, Mathias Hoehn, Uwe Himmelreich, Koen Van Laere, Zeger Debyser, Rik Gijsbers, Veerle Baekelandt
Published 2014-09-01

Face shape and face identity processing in behavioral variant fronto-temporal dementia: A specific deficit for familiarity and name recognition of famous faces

by François-Laurent De Winter, Dorien Timmers, Beatrice de Gelder, Marc Van Orshoven, Marleen Vieren, Miriam Bouckaert, Gert Cypers, Jo Caekebeke, Laura Van de Vliet, Karolien Goffin, Koen Van Laere, Stefan Sunaert, Rik Vandenberghe, Mathieu Vandenbulcke, Jan Van den Stock
Published 2016-01-01

MYCN-induced nucleolar stress drives an early senescence-like transcriptional program in hTERT-immortalized RPE cells

by Sofia Zanotti, Suzanne Vanhauwaert, Christophe Van Neste, Volodimir Olexiouk, Jolien Van Laere, Marlies Verschuuren, Joni Van der Meulen, Liselot M. Mus, Kaat Durinck, Laurentijn Tilleman, Dieter Deforce, Filip Van Nieuwerburgh, Michael D. Hogarty, Bieke Decaesteker, Winnok H. De Vos, Frank Speleman
Published 2021-07-01

NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non‐inflammatory breast cancers

by François Bertucci, Charlotte Rypens, Pascal Finetti, Arnaud Guille, José Adélaïde, Audrey Monneur, Nadine Carbuccia, Séverine Garnier, Piet Dirix, Anthony Gonçalves, Peter Vermeulen, Bisrat G. Debeb, Xiaoping Wang, Luc Dirix, Naoto T. Ueno, Patrice Viens, Massimo Cristofanilli, Max Chaffanet, Daniel Birnbaum, Steven Van Laere
Published 2020-03-01

Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion

by Emilly S. Villodre, Xiaoding Hu, Richard Larson, Pascal Finetti, Kristen Gomez, Wintana Balema, Shane R. Stecklein, Ginette Santiago‐Sanchez, Savitri Krishnamurthy, Juhee Song, Xiaoping Su, Naoto T. Ueno, Debu Tripathy, Steven Van Laere, François Bertucci, Pablo Vivas‐Mejía, Wendy A. Woodward, Bisrat G. Debeb
Published 2021-10-01

Association between the histopathological growth patterns of liver metastases and survival after hepatic surgery in breast cancer patients

by Ali Bohlok, Peter Vermeulen, Sophia Leduc, Emily Latacz, Lara Botzenhart, François Richard, Maxim De Schepper, Tatjana Geukens, Valerio Lucidi, Michail Ignatiadis, Philippe Aftimos, Christos Sotiriou, Martine Piccart, Alain Hendlisz, Steven Van Laere, Luc Dirix, Jean-Christophe Noël, Elia Biganzoli, Denis Larsimont, Christine Desmedt, Vincent Donckier
Published 2020-12-01

Rates of immune cell infiltration in patients with triple-negative breast cancer by molecular subtype.

by Kenichi Harano, Ying Wang, Bora Lim, Robert S Seitz, Stephan W Morris, Daniel B Bailey, David R Hout, Rachel L Skelton, Brian Z Ring, Hiroko Masuda, Arvind U K Rao, Steven Van Laere, Francois Bertucci, Wendy A Woodward, James M Reuben, Savitri Krishnamurthy, Naoto T Ueno
Published 2018-01-01

Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer

by Marie-Julie Nokin, Justine Bellier, Florence Durieux, Olivier Peulen, Gilles Rademaker, Maude Gabriel, Christine Monseur, Benoit Charloteaux, Lieven Verbeke, Steven van Laere, Patrick Roncarati, Michael Herfs, Charles Lambert, Jean Scheijen, Casper Schalkwijk, Alain Colige, Jo Caers, Philippe Delvenne, Andrei Turtoi, Vincent Castronovo, Akeila Bellahcène
Published 2019-01-01

Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern

by Sébastien Tabariès, Matthew G. Annis, Anthoula Lazaris, Stephanie K. Petrillo, Jennifer Huxham, Amri Abdellatif, Vincent Palmieri, Jaclyn Chabot, Radia M. Johnson, Steven Van Laere, Cornelis Verhoef, Yasmina Hachem, Sara Yumeen, Nicholas Meti, Atilla Omeroglu, Gulbeyaz Altinel, Zu-Hua Gao, Alan S. L. Yu, Dirk J. Grünhagen, Peter Vermeulen, Peter Metrakos, Peter M. Siegel
Published 2021-06-01

Early treatment versus expectative management of patent ductus arteriosus in preterm infants: a multicentre, randomised, non-inferiority trial in Europe (BeNeDuctus trial)

by Tim Hundscheid, Wes Onland, Bart van Overmeire, Peter Dijk, Anton H. L. C. van Kaam, Koen P. Dijkman, Elisabeth M. W. Kooi, Eduardo Villamor, André A. Kroon, Remco Visser, Daniel C. Vijlbrief, Susanne M. de Tollenaer, Filip Cools, David van Laere, Anne-Britt Johansson, Catheline Hocq, Alexandra Zecic, Eddy Adang, Rogier Donders, Willem de Vries, Arno F. J. van Heijst, Willem P. de Boode
Published 2018-08-01

Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis

by Markus Mayrhofer, Bram De Laere, Tom Whitington, Peter Van Oyen, Christophe Ghysel, Jozef Ampe, Piet Ost, Wim Demey, Lucien Hoekx, Dirk Schrijvers, Barbara Brouwers, Willem Lybaert, Els Everaert, Daan De Maeseneer, Michiel Strijbos, Alain Bols, Karen Fransis, Steffi Oeyen, Pieter-Jan van Dam, Gert Van den Eynden, Annemie Rutten, Markus Aly, Tobias Nordström, Steven Van Laere, Mattias Rantalainen, Prabhakar Rajan, Lars Egevad, Anders Ullén, Jeffrey Yachnin, Luc Dirix, Henrik Grönberg, Johan Lindberg
Published 2018-11-01

Comparison of New Tau PET-Tracer Candidates With [F]T808 and [F]T807

by Lieven Declercq Pharmacist, Sofie Celen PhD, Joan Lecina PhD, Muneer Ahamed PhD, Thomas Tousseyn Prof, MD, PhD, Diederik Moechars PhD, Jesus Alcazar PhD, Manuela Ariza PhD, Katleen Fierens PhD, Astrid Bottelbergs PhD, Jonas Mariën PhD, Rik Vandenberghe Prof, MD, PhD, Ignacio Jose Andres PhD, Koen Van Laere Prof, MD, PhD, Alfons Verbruggen Prof, PhD, Guy Bormans Prof, PhD
Published 2016-01-01

Tumor vessel co-option probed by single-cell analysis

by Laure-Anne Teuwen, Laura P.M.H. De Rooij, Anne Cuypers, Katerina Rohlenova, Sébastien J. Dumas, Melissa García-Caballero, Elda Meta, Jacob Amersfoort, Federico Taverna, Lisa M. Becker, Nuphar Veiga, Anna Rita Cantelmo, Vincent Geldhof, Nadine V. Conchinha, Joanna Kalucka, Lucas Treps, Lena-Christin Conradi, Shawez Khan, Tobias K. Karakach, Stefaan Soenen, Stefan Vinckier, Luc Schoonjans, Guy Eelen, Steven Van Laere, Mieke Dewerchin, Luc Dirix, Massimiliano Mazzone, Yonglun Luo, Peter Vermeulen, Peter Carmeliet
Published 2021-06-01

The topography of mutational processes in breast cancer genomes

by Sandro Morganella, Ludmil B. Alexandrov, Dominik Glodzik, Xueqing Zou, Helen Davies, Johan Staaf, Anieta M. Sieuwerts, Arie B. Brinkman, Sancha Martin, Manasa Ramakrishna, Adam Butler, Hyung-Yong Kim, Åke Borg, Christos Sotiriou, P. Andrew Futreal, Peter J. Campbell, Paul N. Span, Steven Van Laere, Sunil R. Lakhani, Jorunn E. Eyfjord, Alastair M. Thompson, Hendrik G. Stunnenberg, Marc J. van de Vijver, John W. M. Martens, Anne-Lise Børresen-Dale, Andrea L. Richardson, Gu Kong, Gilles Thomas, Julian Sale, Cristina Rada, Michael R. Stratton, Ewan Birney, Serena Nik-Zainal
Published 2016-05-01

Application of advanced brain positron emission tomography–based molecular imaging for a biological framework in neurodegenerative proteinopathies

by Daniela Perani, Leonardo Iaccarino, Andreas H. Jacobs, IMBI Brain Imaging Working Group, Adriaan A. Lammertsma, Agneta Nordberg, Albert D. Windhorst, Alexander Gerhard, Alexandra Winkeler, Andreas H. Jacobs, Anthony Gee, Bertrand Kuhnast, Christer Halldin, Daniela Perani, David Brooks, Elena Rodriguez‐Vieitez, Federico E. Turkheimer, Francisco López‐Picón, Gitte M. Knudsen, Johnny Vercouillie, Juha O. Rinne, Karl Herholz, Koen Van Laere, Andrea Varrone, Marie Joao Santiago‐Ribeiro, Matthias M. Herth, Michael A. Carroll, Sylvie Chalon, Michel Bottlaender, Oskar Hansson, Paul Edison, Rainer Hinz, Ronald Boellaard, Rosa Maria Moresco, Sabina Pappata
Published 2019-12-01

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

by Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne J. F. Kaptein, Rong Li, Valentijn Vergote, Laura Seldeslachts, Johan Van Weyenbergh, Carolien De Keyzer, Lindsey Bervoets, Sapna Sharma, Laurens Liesenborghs, Ji Ma, Sander Jansen, Dominique Van Looveren, Thomas Vercruysse, Xinyu Wang, Dirk Jochmans, Erik Martens, Kenny Roose, Dorien De Vlieger, Bert Schepens, Tina Van Buyten, Sofie Jacobs, Yanan Liu, Joan Martí-Carreras, Bert Vanmechelen, Tony Wawina-Bokalanga, Leen Delang, Joana Rocha-Pereira, Lotte Coelmont, Winston Chiu, Pieter Leyssen, Elisabeth Heylen, Dominique Schols, Lanjiao Wang, Lila Close, Jelle Matthijnssens, Marc Van Ranst, Veerle Compernolle, Georg Schramm, Koen Van Laere, Xavier Saelens, Nico Callewaert, Ghislain Opdenakker, Piet Maes, Birgit Weynand, Christopher Cawthorne, Greetje Vande Velde, Zhongde Wang, Johan Neyts, Kai Dallmeier
Published 2020-11-01

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

by Marcel Smid, F. Germán Rodríguez-González, Anieta M. Sieuwerts, Roberto Salgado, Wendy J. C. Prager-Van der Smissen, Michelle van der Vlugt-Daane, Anne van Galen, Serena Nik-Zainal, Johan Staaf, Arie B. Brinkman, Marc J. van de Vijver, Andrea L. Richardson, Aquila Fatima, Kim Berentsen, Adam Butler, Sancha Martin, Helen R. Davies, Reno Debets, Marion E. Meijer-Van Gelder, Carolien H. M. van Deurzen, Gaëtan MacGrogan, Gert G. G. M. Van den Eynden, Colin Purdie, Alastair M. Thompson, Carlos Caldas, Paul N. Span, Peter T. Simpson, Sunil R. Lakhani, Steven Van Laere, Christine Desmedt, Markus Ringnér, Stefania Tommasi, Jorunn Eyford, Annegien Broeks, Anne Vincent-Salomon, P. Andrew Futreal, Stian Knappskog, Tari King, Gilles Thomas, Alain Viari, Anita Langerød, Anne-Lise Børresen-Dale, Ewan Birney, Hendrik G. Stunnenberg, Mike Stratton, John A. Foekens, John W. M. Martens
Published 2016-09-01