In Vitro Evaluation of a Peptide-Mesoporous Silica Nanoparticle Drug Release System against HIV-1

by Katharina Braun, Christina M. Stürzel, Frank Kirchhoff, Mika Lindén
Published 2020-07-01

Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance

by Dorota Kmiec, Shilpa S. Iyer, Christina M. Sturzel, Daniel Sauter, Beatrice H. Hahn, Frank Kirchhoff
Published 2016-08-01

Convergent Evolution of HLA-C Downmodulation in HIV-1 and HIV-2

by Kristina Hopfensperger, Jonathan Richard, Christina M. Stürzel, Frederic Bibollet-Ruche, Richard Apps, Marie Leoz, Jean-Christophe Plantier, Beatrice H. Hahn, Andrés Finzi, Frank Kirchhoff, Daniel Sauter
Published 2020-07-01

An additional NF-κB site allows HIV-1 subtype C to evade restriction by nuclear PYHIN proteins

by Matteo Bosso, Christina M. Stürzel, Dorota Kmiec, Smitha Srinivasachar Badarinarayan, Elisabeth Braun, Jumpei Ito, Kei Sato, Beatrice H. Hahn, Konstantin M.J. Sparrer, Daniel Sauter, Frank Kirchhoff
Published 2021-09-01

CpG Frequency in the 5′ Third of the env Gene Determines Sensitivity of Primary HIV-1 Strains to the Zinc-Finger Antiviral Protein

by Dorota Kmiec, Rayhane Nchioua, Scott Sherrill-Mix, Christina M. Stürzel, Elena Heusinger, Elisabeth Braun, Marcos V. P. Gondim, Dominik Hotter, Konstantin M. J. Sparrer, Beatrice H. Hahn, Daniel Sauter, Frank Kirchhoff
Published 2020-01-01

Differential Regulation of NF-κB-Mediated Proviral and Antiviral Host Gene Expression by Primate Lentiviral Nef and Vpu Proteins

by Daniel Sauter, Dominik Hotter, Benoît Van Driessche, Christina M. Stürzel, Silvia F. Kluge, Steffen Wildum, Hangxing Yu, Bernd Baumann, Thomas Wirth, Jean-Christophe Plantier, Marie Leoz, Beatrice H. Hahn, Carine Van Lint, Frank Kirchhoff
Published 2015-02-01

SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue.

by Dorota Kmiec, Bengisu Akbil, Swetha Ananth, Dominik Hotter, Konstantin M J Sparrer, Christina M Stürzel, Birthe Trautz, Ahidjo Ayouba, Martine Peeters, Zhong Yao, Igor Stagljar, Vânia Passos, Thomas Zillinger, Christine Goffinet, Daniel Sauter, Oliver T Fackler, Frank Kirchhoff
Published 2018-08-01

Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses

by Jonathan Richard, Jéréémie Prééévost, Amy E. Baxter, Benjamin von Bredow, Shilei Ding, Halima Medjahed, Gloria G. Delgado, Nathalie Brassard, Christina M. Sturzel, Frank Kirchhoff, Beatrice H. Hahn, Matthew S. Parsons, Daniel E. Kaufmann, David T. Evans, Andréééés Finzi, Stephen P. Goff
Published 2018-03-01

Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.

by Matteo Bosso, Caterina Prelli Bozzo, Dominik Hotter, Meta Volcic, Christina M Stürzel, Annika Rammelt, Yi Ni, Stephan Urban, Miriam Becker, Mario Schelhaas, Sabine Wittmann, Maria H Christensen, Florian I Schmidt, Thomas Gramberg, Konstantin M J Sparrer, Daniel Sauter, Frank Kirchhoff
Published 2020-08-01

Upregulation of BST-2 by Type I Interferons Reduces the Capacity of Vpu To Protect HIV-1-Infected Cells from NK Cell Responses

by Jérémie Prévost, Suzanne Pickering, Mitchell J. Mumby, Halima Medjahed, Gabrielle Gendron-Lepage, Gloria G. Delgado, Brennan S. Dirk, Jimmy D. Dikeakos, Christina M. Stürzel, Daniel Sauter, Frank Kirchhoff, Frederic Bibollet-Ruche, Beatrice H. Hahn, Mathieu Dubé, Daniel E. Kaufmann, Stuart J. D. Neil, Andrés Finzi, Jonathan Richard
Published 2019-06-01

SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity

by Nicolas Huot, Philippe Rascle, Caroline Petitdemange, Vanessa Contreras, Christina M. Stürzel, Eduard Baquero, Justin L. Harper, Caroline Passaes, Rachel Legendre, Hugo Varet, Yoann Madec, Ulrike Sauermann, Christiane Stahl-Hennig, Jacob Nattermann, Asier Saez-Cirion, Roger Le Grand, R. Keith Reeves, Mirko Paiardini, Frank Kirchhoff, Beatrice Jacquelin, Michaela Müller-Trutwin
Published 2021-02-01

Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.

by Jason A Neidleman, Joseph C Chen, Nargis Kohgadai, Janis A Müller, Anders Laustsen, Karthiga Thavachelvam, Karen S Jang, Christina M Stürzel, Jennifer J Jones, Christina Ochsenbauer, Avantika Chitre, Ma Somsouk, Maurice M Garcia, James F Smith, Ruth M Greenblatt, Jan Münch, Martin R Jakobsen, Linda C Giudice, Warner C Greene, Nadia R Roan
Published 2017-02-01

Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity

by Simone Joas, Erica H. Parrish, Clement W. Gnanadurai, Edina Lump, Christina M. Stürzel, Nicholas F. Parrish, Gerald H. Learn, Ulrike Sauermann, Berit Neumann, Kerstin Mätz Rensing, Dietmar Fuchs, James M. Billingsley, Steven E. Bosinger, Guido Silvestri, Cristian Apetrei, Nicolas Huot, Thalia Garcia-Tellez, Michaela Müller-Trutwin, Dominik Hotter, Daniel Sauter, Christiane Stahl-Hennig, Beatrice H. Hahn, Frank Kirchhoff
Published 2018-04-01

IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro

by Caterina Prelli Bozzo, Rayhane Nchioua, Meta Volcic, Lennart Koepke, Jana Krüger, Desiree Schütz, Sandra Heller, Christina M. Stürzel, Dorota Kmiec, Carina Conzelmann, Janis Müller, Fabian Zech, Elisabeth Braun, Rüdiger Groß, Lukas Wettstein, Tatjana Weil, Johanna Weiß, Federica Diofano, Armando A. Rodríguez Alfonso, Sebastian Wiese, Daniel Sauter, Jan Münch, Christine Goffinet, Alberto Catanese, Michael Schön, Tobias M. Boeckers, Steffen Stenger, Kei Sato, Steffen Just, Alexander Kleger, Konstantin M. J. Sparrer, Frank Kirchhoff
Published 2021-07-01

A molecular tweezer antagonizes seminal amyloids and HIV infection

by Edina Lump, Laura M Castellano, Christoph Meier, Janine Seeliger, Nelli Erwin, Benjamin Sperlich, Christina M Stürzel, Shariq Usmani, Rebecca M Hammond, Jens von Einem, Gisa Gerold, Florian Kreppel, Kenny Bravo-Rodriguez, Thomas Pietschmann, Veronica M Holmes, David Palesch, Onofrio Zirafi, Drew Weissman, Andrea Sowislok, Burkhard Wettig, Christian Heid, Frank Kirchhoff, Tanja Weil, Frank-Gerrit Klärner, Thomas Schrader, Gal Bitan, Elsa Sanchez-Garcia, Roland Winter, James Shorter, Jan Münch
Published 2015-08-01