Differential requirement for the CD45 splicing regulator hnRNPLL for accumulation of NKT and conventional T cells.

by Mehmet Yabas, Dale I Godfrey, Christopher C Goodnow, Gerard F Hoyne
Published 2011-01-01

DeepSNVMiner: a sequence analysis tool to detect emergent, rare mutations in subsets of cell populations

by T. Daniel Andrews, Yogesh Jeelall, Dipti Talaulikar, Christopher C. Goodnow, Matthew A. Field
Published 2016-05-01

Preponderance of CTLA4 Variation Associated With Autosomal Dominant Immune Dysregulation in the MYPPPY Motif

by Owen M. Siggs, Owen M. Siggs, Amanda Russell, Davinder Singh-Grewal, Melanie Wong, Pearl Chan, Maria E. Craig, Ted O'Loughlin, Michael Stormon, Christopher C. Goodnow, Christopher C. Goodnow
Published 2019-07-01

The Ubiquitin Ligase Adaptor NDFIP1 Selectively Enforces a CD8+ T Cell Tolerance Checkpoint to High-Dose Antigen

by Mayura V. Wagle, Julia M. Marchingo, Jason Howitt, Seong-Seng Tan, Christopher C. Goodnow, Ian A. Parish
Published 2018-07-01

A missense mutation in the transcription factor ETV5 leads to sterility, increased embryonic and perinatal death, postnatal growth restriction, renal asymmetry and polydactyly in t...

by Duangporn Jamsai, Brett J Clark, Stephanie J Smith, Belinda Whittle, Christopher C Goodnow, Christopher J Ormandy, Moira K O'Bryan
Published 2013-01-01

IgD attenuates the IgM-induced anergy response in transitional and mature B cells

by Zahra Sabouri, Samuel Perotti, Emily Spierings, Peter Humburg, Mehmet Yabas, Hannes Bergmann, Keisuke Horikawa, Carla Roots, Samantha Lambe, Clara Young, T. Dan Andrews, Matthew Field, Anselm Enders, Joanne H. Reed, Christopher C. Goodnow
Published 2016-11-01

High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes

by Mandeep Singh, Ghamdan Al-Eryani, Shaun Carswell, James M. Ferguson, James Blackburn, Kirston Barton, Daniel Roden, Fabio Luciani, Tri Giang Phan, Simon Junankar, Katherine Jackson, Christopher C. Goodnow, Martin A. Smith, Alexander Swarbrick
Published 2019-07-01

Heterogeneity of Human Neutrophil CD177 Expression Results from CD177P1 Pseudogene Conversion.

by Zuopeng Wu, Rong Liang, Thomas Ohnesorg, Vicky Cho, Wesley Lam, Walter P Abhayaratna, Paul A Gatenby, Chandima Perera, Yafei Zhang, Belinda Whittle, Andrew Sinclair, Christopher C Goodnow, Matthew Field, T Daniel Andrews, Matthew C Cook
Published 2016-05-01

CD45-mediated control of TCR tuning in naïve and memory CD8+ T cells

by Jae-Ho Cho, Hee-Ok Kim, Young-Jun Ju, Yoon-Chul Kye, Gil-Woo Lee, Sung-Woo Lee, Cheol-Heui Yun, Nunzio Bottini, Kylie Webster, Christopher C. Goodnow, Charles D. Surh, Cecile King, Jonathan Sprent
Published 2016-11-01

RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility.

by Moira K O'Bryan, Brett J Clark, Eileen A McLaughlin, Rebecca J D'Sylva, Liza O'Donnell, Jacqueline A Wilce, Jessie Sutherland, Anne E O'Connor, Belinda Whittle, Christopher C Goodnow, Christopher J Ormandy, Duangporn Jamsai
Published 2013-01-01

Correction: HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.

by Shu Ly Lim, Zhi Peng Qu, R Daniel Kortschak, David M Lawrence, Joel Geoghegan, Anna-Lena Hempfling, Martin Bergmann, Christopher C Goodnow, Christopher J Ormandy, Lee Wong, Jeff Mann, Hamish S Scott, Duangporn Jamsai, David L Adelson, Moira K O'Bryan
Published 2015-12-01

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.

by Jennifer C Y Lo, Duangporn Jamsai, Anne E O'Connor, Claire Borg, Brett J Clark, James C Whisstock, Mark C Field, Vicki Adams, Tomomoto Ishikawa, R John Aitken, Belinda Whittle, Christopher C Goodnow, Christopher J Ormandy, Moira K O'Bryan
Published 2012-01-01

HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.

by Shu Ly Lim, Zhi Peng Qu, R Daniel Kortschak, David M Lawrence, Joel Geoghegan, Anna-Lena Hempfling, Martin Bergmann, Christopher C Goodnow, Christopher J Ormandy, Lee Wong, Jeff Mann, Hamish S Scott, Duangporn Jamsai, David L Adelson, Moira K O'Bryan
Published 2015-10-01

Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation

by Roybel R Ramiscal, Ian A Parish, Robert S Lee-Young, Jeffrey J Babon, Julianna Blagih, Alvin Pratama, Jaime Martin, Naomi Hawley, Jean Y Cappello, Pablo F Nieto, Julia I Ellyard, Nadia J Kershaw, Rebecca A Sweet, Christopher C Goodnow, Russell G Jones, Mark A Febbraio, Carola G Vinuesa, Vicki Athanasopoulos
Published 2015-10-01

Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis.

by Chad K Heazlewood, Matthew C Cook, Rajaraman Eri, Gareth R Price, Sharyn B Tauro, Douglas Taupin, David J Thornton, Chin Wen Png, Tanya L Crockford, Richard J Cornall, Rachel Adams, Masato Kato, Keats A Nelms, Nancy A Hong, Timothy H J Florin, Christopher C Goodnow, Michael A McGuckin
Published 2008-03-01

Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations.

by Katherine R Bull, Andrew J Rimmer, Owen M Siggs, Lisa A Miosge, Carla M Roots, Anselm Enders, Edward M Bertram, Tanya L Crockford, Belinda Whittle, Paul K Potter, Michelle M Simon, Ann-Marie Mallon, Steve D M Brown, Bruce Beutler, Christopher C Goodnow, Gerton Lunter, Richard J Cornall
Published 2013-01-01

Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies

by Stephen R Daley, Kristen M Coakley, Daniel Y Hu, Katrina L Randall, Craig N Jenne, Andre Limnander, Darienne R Myers, Noelle K Polakos, Anselm Enders, Carla Roots, Bhavani Balakishnan, Lisa A Miosge, Geoff Sjollema, Edward M Bertram, Matthew A Field, Yunli Shao, T Daniel Andrews, Belinda Whittle, S Whitney Barnes, John R Walker, Jason G Cyster, Christopher C Goodnow, Jeroen P Roose
Published 2013-12-01

A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.

by Samantha R Oakes, David Gallego-Ortega, Prudence M Stanford, Simon Junankar, Wendy Wing Yee Au, Zoya Kikhtyak, Anita von Korff, Claudio M Sergio, Andrew M K Law, Lesley E Castillo, Stephanie L Allerdice, Adelaide I J Young, Catherine Piggin, Belinda Whittle, Edward Bertram, Matthew J Naylor, Daniel L Roden, Jesse Donovan, Alexei Korennykh, Christopher C Goodnow, Moira K O'Bryan, Christopher J Ormandy
Published 2017-11-01

Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance

by Mayura V. Wagle, Stephin J. Vervoort, Madison J. Kelly, Willem Van Der Byl, Timothy J. Peters, Ben P. Martin, Luciano G. Martelotto, Simone Nüssing, Kelly M. Ramsbottom, James R. Torpy, Deborah Knight, Sinead Reading, Kevin Thia, Lisa A. Miosge, Debbie R. Howard, Renee Gloury, Sarah S. Gabriel, Daniel T. Utzschneider, Jane Oliaro, Jonathan D. Powell, Fabio Luciani, Joseph A. Trapani, Ricky W. Johnstone, Axel Kallies, Christopher C. Goodnow, Ian A. Parish
Published 2021-05-01