Translating DNA into synthetic molecules.

by David R Liu
Published 2004-07-01

Phage-assisted continuous evolution of proteases with altered substrate specificity

by Michael S. Packer, Holly A. Rees, David R. Liu
Published 2017-10-01

Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation

by Weixin Tang, Johnny H. Hu, David R. Liu
Published 2017-06-01

Development of hRad51–Cas9 nickase fusions that mediate HDR without double-stranded breaks

by Holly A. Rees, Wei-Hsi Yeh, David R. Liu
Published 2019-05-01

An anionic human protein mediates cationic liposome delivery of genome editing proteins into mammalian cells

by Y. Bill Kim, Kevin T. Zhao, David B. Thompson, David R. Liu
Published 2019-07-01

In vivo base editing of post-mitotic sensory cells

by Wei-Hsi Yeh, Hao Chiang, Holly A. Rees, Albert S. B. Edge, David R. Liu
Published 2018-06-01

The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing.

by Yun Huang, William A Pastor, Yinghua Shen, Mamta Tahiliani, David R Liu, Anjana Rao
Published 2010-01-01

Targeting fidelity of adenine and cytosine base editors in mouse embryos

by Hye Kyung Lee, Michaela Willi, Shannon M. Miller, Sojung Kim, Chengyu Liu, David R. Liu, Lothar Hennighausen
Published 2018-11-01

Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery

by Holly A. Rees, Alexis C. Komor, Wei-Hsi Yeh, Joana Caetano-Lopes, Matthew Warman, Albert S. B. Edge, David R. Liu
Published 2017-06-01

In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A

by Hyun Ok Ham, Zheng Qu, Carolyn A. Haller, Brent M. Dorr, Erbin Dai, Wookhyun Kim, David R. Liu, Elliot L. Chaikof
Published 2016-04-01

Addendum: High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases

by Jeffrey L. Bessen, Lena K. Afeyan, Vlado Dančík, Luke W. Koblan, David B. Thompson, Chas Leichner, Paul A. Clemons, David R. Liu
Published 2019-07-01

High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases

by Jeffrey L. Bessen, Lena K. Afeyan, Vlado Dančík, Luke W. Koblan, David B. Thompson, Chas Leichner, Paul A. Clemons, David R. Liu
Published 2019-04-01

Inhibition of bacterial conjugation by phage M13 and its protein g3p: quantitative analysis and model.

by Abraham Lin, Jose Jimenez, Julien Derr, Pedro Vera, Michael L Manapat, Kevin M Esvelt, Laura Villanueva, David R Liu, Irene A Chen
Published 2011-01-01

PrimeDesign software for rapid and simplified design of prime editing guide RNAs

by Jonathan Y. Hsu, Julian Grünewald, Regan Szalay, Justine Shih, Andrew V. Anzalone, Kin Chung Lam, Max W. Shen, Karl Petri, David R. Liu, J. Keith Joung, Luca Pinello
Published 2021-02-01

Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope

by Tingting Jiang, Jordana M. Henderson, Kevin Coote, Yi Cheng, Hillary C. Valley, Xiao-Ou Zhang, Qin Wang, Luke H. Rhym, Yueying Cao, Gregory A. Newby, Hermann Bihler, Martin Mense, Zhiping Weng, Daniel G. Anderson, Anton P. McCaffrey, David R. Liu, Wen Xue
Published 2020-04-01

Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression

by Pan Gao, Qing Lyu, Amr R. Ghanam, Cicera R. Lazzarotto, Gregory A. Newby, Wei Zhang, Mihyun Choi, Orazio J. Slivano, Kevin Holden, John A. Walker, Anastasia P. Kadina, Rob J. Munroe, Christian M. Abratte, John C. Schimenti, David R. Liu, Shengdar Q. Tsai, Xiaochun Long, Joseph M. Miano
Published 2021-03-01

Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme

by Zhening Zhang, Wenguang G Liang, Lucas J Bailey, Yong Zi Tan, Hui Wei, Andrew Wang, Mara Farcasanu, Virgil A Woods, Lauren A McCord, David Lee, Weifeng Shang, Rebecca Deprez-Poulain, Benoit Deprez, David R Liu, Akiko Koide, Shohei Koide, Anthony A Kossiakoff, Sheng Li, Bridget Carragher, Clinton S Potter, Wei-Jen Tang
Published 2018-03-01