Polar localization of virulence-related Esx-1 secretion in mycobacteria.

by Fredric Carlsson, Shilpa A Joshi, Linda Rangell, Eric J Brown
Published 2009-01-01

Atg5-independent sequestration of ubiquitinated mycobacteria.

by Cathleen A Collins, Ann De Mazière, Suzanne van Dijk, Fredric Carlsson, Judith Klumperman, Eric J Brown
Published 2009-05-01

ATR suppresses endogenous DNA damage and allows completion of homologous recombination repair.

by Adam D Brown, Brian W Sager, Aparna Gorthi, Sonal S Tonapi, Eric J Brown, Alexander J R Bishop
Published 2014-01-01

A mycobacterium ESX-1-secreted virulence factor with unique requirements for export.

by Bryant McLaughlin, Janet S Chon, Jason A MacGurn, Fredric Carlsson, Terri L Cheng, Jeffery S Cox, Eric J Brown
Published 2007-08-01

Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection.

by Fredric Carlsson, Janice Kim, Calin Dumitru, Kai H Barck, Richard A D Carano, Mei Sun, Lauri Diehl, Eric J Brown
Published 2010-05-01

RPA Accumulation during Class Switch Recombination Represents 5′–3′ DNA-End Resection during the S–G2/M Phase of the Cell Cycle

by Arito Yamane, Davide F. Robbiani, Wolfgang Resch, Anne Bothmer, Hirotaka Nakahashi, Thiago Oliveira, Philipp C. Rommel, Eric J. Brown, Andre Nussenzweig, Michel C. Nussenzweig, Rafael Casellas
Published 2013-01-01

Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins

by Alexandra M Whiteley, Miguel A Prado, Ivan Peng, Alexander R Abbas, Benjamin Haley, Joao A Paulo, Mike Reichelt, Anand Katakam, Meredith Sagolla, Zora Modrusan, Dong Yun Lee, Merone Roose-Girma, Donald S Kirkpatrick, Brent S McKenzie, Steven P Gygi, Daniel Finley, Eric J Brown
Published 2017-09-01

Systematic genetic nomenclature for type VII secretion systems.

by Wilbert Bitter, Edith N G Houben, Daria Bottai, Priscille Brodin, Eric J Brown, Jeffery S Cox, Keith Derbyshire, Sarah M Fortune, Lian-Yong Gao, Jun Liu, Nicolaas C Gey van Pittius, Alexander S Pym, Eric J Rubin, David R Sherman, Stewart T Cole, Roland Brosch
Published 2009-10-01

Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models

by Hyoung Kim, Haineng Xu, Erin George, Dorothy Hallberg, Sushil Kumar, Veena Jagannathan, Sergey Medvedev, Yasuto Kinose, Kyle Devins, Priyanka Verma, Kevin Ly, Yifan Wang, Roger A. Greenberg, Lauren Schwartz, Neil Johnson, Robert B. Scharpf, Gordon B. Mills, Rugang Zhang, Victor E. Velculescu, Eric J. Brown, Fiona Simpkins
Published 2020-07-01

CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models

by Haineng Xu, Erin George, Yasuto Kinose, Hyoung Kim, Jennifer B. Shah, Jasmine D. Peake, Benjamin Ferman, Sergey Medvedev, Thomas Murtha, Carter J. Barger, Kyle M. Devins, Kurt D’Andrea, Bradley Wubbenhorst, Lauren E. Schwartz, Wei-Ting Hwang, Gordon B. Mills, Katherine L. Nathanson, Adam R. Karpf, Ronny Drapkin, Eric J. Brown, Fiona Simpkins
Published 2021-09-01

A Putative Bacterial ABC Transporter Circumvents the Essentiality of Signal Peptidase

by J. Hiroshi Morisaki, Peter A. Smith, Shailesh V. Date, Kimberly K. Kajihara, Chau Linda Truong, Zora Modrusan, Donghong Yan, Jing Kang, Min Xu, Ishita M. Shah, Robert Mintzer, Eric M. Kofoed, Tommy K. Cheung, David Arnott, Michael F. T. Koehler, Christopher E. Heise, Eric J. Brown, Man-Wah Tan, Wouter L. W. Hazenbos
Published 2016-09-01

Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins.

by Wouter L W Hazenbos, Kimberly K Kajihara, Richard Vandlen, J Hiroshi Morisaki, Sophie M Lehar, Mark J Kwakkenbos, Tim Beaumont, Arjen Q Bakker, Qui Phung, Lee R Swem, Satish Ramakrishnan, Janice Kim, Min Xu, Ishita M Shah, Binh An Diep, Tao Sai, Andrew Sebrell, Yana Khalfin, Angela Oh, Chris Koth, S Jack Lin, Byoung-Chul Lee, Magnus Strandh, Klaus Koefoed, Peter S Andersen, Hergen Spits, Eric J Brown, Man-Wah Tan, Sanjeev Mariathasan
Published 2013-01-01