A robust and efficient method for Mendelian randomization with hundreds of genetic variants

by Stephen Burgess, Christopher N Foley, Elias Allara, James R Staley, Joanna M. M. Howson
Published 2020-01-01

Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants

by Elodie Persyn, Ken B. Hanscombe, Joanna M. M. Howson, Cathryn M. Lewis, Matthew Traylor, Hugh S. Markus
Published 2020-05-01

A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits

by Christopher N. Foley, James R. Staley, Philip G. Breen, Benjamin B. Sun, Paul D. W. Kirk, Stephen Burgess, Joanna M. M. Howson
Published 2021-02-01

Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

by Gad Abraham, Rainer Malik, Ekaterina Yonova-Doing, Agus Salim, Tingting Wang, John Danesh, Adam S. Butterworth, Joanna M. M. Howson, Michael Inouye, Martin Dichgans
Published 2019-12-01

Author Correction: Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

by Gad Abraham, Rainer Malik, Ekaterina Yonova-Doing, Agus Salim, Tingting Wang, John Danesh, Adam S. Butterworth, Joanna M. M. Howson, Michael Inouye, Martin Dichgans
Published 2020-02-01

Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

by Vincent Plagnol, Joanna M M Howson, Deborah J Smyth, Neil Walker, Jason P Hafler, Chris Wallace, Helen Stevens, Laura Jackson, Matthew J Simmonds, Type 1 Diabetes Genetics Consortium, Polly J Bingley, Stephen C Gough, John A Todd
Published 2011-08-01

Mendelian randomization for studying the effects of perturbing drug targets [version 2; peer review: 2 approved, 1 approved with reservations]

by Dipender Gill, Marios K. Georgakis, Venexia M. Walker, A. Floriaan Schmidt, Apostolos Gkatzionis, Daniel F. Freitag, Chris Finan, Aroon D. Hingorani, Joanna M.M. Howson, Stephen Burgess, Daniel I. Swerdlow, George Davey Smith, Michael V. Holmes, Martin Dichgans, Robert A Scott, Jie Zheng, Bruce M. Psaty, Neil M. Davies
Published 2021-02-01

Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases.

by Ricardo C Ferreira, Daniel F Freitag, Antony J Cutler, Joanna M M Howson, Daniel B Rainbow, Deborah J Smyth, Stephen Kaptoge, Pamela Clarke, Charlotte Boreham, Richard M Coulson, Marcin L Pekalski, Wei-Min Chen, Suna Onengut-Gumuscu, Stephen S Rich, Adam S Butterworth, Anders Malarstig, John Danesh, John A Todd
Published 2013-04-01

Assessing the causal association of glycine with risk of cardio-metabolic diseases

by Laura B. L. Wittemans, Luca A. Lotta, Clare Oliver-Williams, Isobel D. Stewart, Praveen Surendran, Savita Karthikeyan, Felix R. Day, Albert Koulman, Fumiaki Imamura, Lingyao Zeng, Jeanette Erdmann, Heribert Schunkert, Kay-Tee Khaw, Julian L. Griffin, Nita G. Forouhi, Robert A. Scott, Angela M. Wood, Stephen Burgess, Joanna M. M. Howson, John Danesh, Nicholas J. Wareham, Adam S. Butterworth, Claudia Langenberg
Published 2019-03-01

A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis

by Steven Bell, Andreas S. Rigas, Magnus K. Magnusson, Egil Ferkingstad, Elias Allara, Gyda Bjornsdottir, Anna Ramond, Erik Sørensen, Gisli H. Halldorsson, Dirk S. Paul, Kristoffer S. Burgdorf, Hannes P. Eggertsson, Joanna M. M. Howson, Lise W. Thørner, Snaedis Kristmundsdottir, William J. Astle, Christian Erikstrup, Jon K. Sigurdsson, Dragana Vuckovic, Khoa M. Dinh, Vinicius Tragante, Praveen Surendran, Ole B. Pedersen, Brynjar Vidarsson, Tao Jiang, Helene M. Paarup, Pall T. Onundarson, Parsa Akbari, Kaspar R. Nielsen, Sigrun H. Lund, Kristinn Juliusson, Magnus I. Magnusson, Michael L. Frigge, Asmundur Oddsson, Isleifur Olafsson, Stephen Kaptoge, Henrik Hjalgrim, Gudmundur Runarsson, Angela M. Wood, Ingileif Jonsdottir, Thomas F. Hansen, Olof Sigurdardottir, Hreinn Stefansson, David Rye, DBDS Genomic Consortium, James E. Peters, David Westergaard, Hilma Holm, Nicole Soranzo, Karina Banasik, Gudmar Thorleifsson, Willem H. Ouwehand, Unnur Thorsteinsdottir, David J. Roberts, Patrick Sulem, Adam S. Butterworth, Daniel F. Gudbjartsson, John Danesh, Søren Brunak, Emanuele Di Angelantonio, Henrik Ullum, Kari Stefansson
Published 2021-02-01