B cells and the humoral response in melanoma: The overlooked players of the tumor microenvironment

by Giulia Chiaruttini, Silvia Mele, James Opzoomer, Silvia Crescioli, Kristina M. Ilieva, Katie E. Lacy, Sophia N. Karagiannis
Published 2017-04-01

A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma

by Ricarda M. Hoffmann, Silvia Crescioli, Silvia Mele, Eirini Sachouli, Anthony Cheung, Connie K. Chui, Paolo Andriollo, Paul J. M. Jackson, Katie E. Lacy, James F. Spicer, David E. Thurston, Sophia N. Karagiannis
Published 2020-04-01

IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural statesResearch in context

by Giulia Pellizzari, Coran Hoskin, Silvia Crescioli, Silvia Mele, Jelena Gotovina, Giulia Chiaruttini, Rodolfo Bianchini, Kristina Ilieva, Heather J. Bax, Sophie Papa, Katie E. Lacy, Erika Jensen-Jarolim, Sophia Tsoka, Debra H. Josephs, James F. Spicer, Sophia N. Karagiannis
Published 2019-05-01

Immune mediator expression signatures are associated with improved outcome in ovarian carcinoma

by Mano Nakamura, Heather J. Bax, Daniele Scotto, Elmira Amiri Souri, Sam Sollie, Robert J. Harris, Niklas Hammar, Goran Walldius, Anna Winship, Sharmistha Ghosh, Ana Montes, James F. Spicer, Mieke Van Hemelrijck, Debra H. Josephs, Katie E. Lacy, Sophia Tsoka, Sophia N. Karagiannis
Published 2019-06-01

Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types

by Kristina M. Ilieva, Kristina M. Ilieva, Anthony Cheung, Anthony Cheung, Silvia Mele, Giulia Chiaruttini, Silvia Crescioli, Merope Griffin, Mano Nakamura, Mano Nakamura, James F. Spicer, Sophia Tsoka, Katie E. Lacy, Andrew N. J. Tutt, Andrew N. J. Tutt, Sophia N. Karagiannis, Sophia N. Karagiannis
Published 2018-01-01

IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype

by Mano Nakamura, Elmira Amiri Souri, Gabriel Osborn, Roman Laddach, Jitesh Chauhan, Chara Stavraka, Sara Lombardi, Anna Black, Atousa Khiabany, Duaa O. Khair, Mariangela Figini, Anna Winship, Sharmistha Ghosh, Ana Montes, James F. Spicer, Heather J. Bax, Debra H. Josephs, Katie E. Lacy, Sophia Tsoka, Sophia N. Karagiannis
Published 2020-11-01

Immunotherapy using IgE or CAR T cells for cancers expressing the tumor antigen SLC3A2

by Debra H Josephs, Giulia Pellizzari, Olivier Martinez, Silvia Crescioli, Robert Page, Ashley Di Meo, Silvia Mele, Giulia Chiaruttini, Jan Hoinka, Ihor Batruch, Ioannis Prassas, Melanie Grandits, Jacobo López-Abente, Eva Bugallo-Blanco, Malcolm Ward, Heather J Bax, Elise French, Anthony Cheung, Sara Lombardi, Mariangela Figini, Katie E Lacy, Eleftherios P Diamandis
Published 2021-06-01

Evaluation of Antigen-Conjugated Fluorescent Beads to Identify Antigen-Specific B Cells

by Isabel Correa, Isabel Correa, Kristina M. Ilieva, Kristina M. Ilieva, Kristina M. Ilieva, Silvia Crescioli, Silvia Crescioli, Sara Lombardi, Mariangela Figini, Anthony Cheung, Anthony Cheung, James F. Spicer, Andrew N. J. Tutt, Andrew N. J. Tutt, Frank O. Nestle, Frank O. Nestle, Frank O. Nestle, Panagiotis Karagiannis, Panagiotis Karagiannis, Panagiotis Karagiannis, Katie E. Lacy, Sophia N. Karagiannis, Sophia N. Karagiannis, Sophia N. Karagiannis
Published 2018-03-01

B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies

by Zena N. Willsmore, Robert J. Harris, Silvia Crescioli, Khuluud Hussein, Helen Kakkassery, Deepika Thapa, Anthony Cheung, Anthony Cheung, Jitesh Chauhan, Heather J. Bax, Heather J. Bax, Alicia Chenoweth, Alicia Chenoweth, Roman Laddach, Roman Laddach, Gabriel Osborn, Alexa McCraw, Ricarda M. Hoffmann, Mano Nakamura, Jenny L. Geh, Alastair MacKenzie-Ross, Ciaran Healy, Sophia Tsoka, James F. Spicer, Sophie Papa, Sophie Papa, Linda Barber, Katie E. Lacy, Sophia N. Karagiannis, Sophia N. Karagiannis
Published 2021-01-01

Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma

by Duaa O. Khair, Heather J. Bax, Heather J. Bax, Silvia Mele, Silvia Crescioli, Giulia Pellizzari, Atousa Khiabany, Mano Nakamura, Robert J. Harris, Elise French, Ricarda M. Hoffmann, Ricarda M. Hoffmann, Iwan P. Williams, Anthony Cheung, Anthony Cheung, Benjamin Thair, Charlie T. Beales, Emma Touizer, Adrian W. Signell, Nahrin L. Tasnova, James F. Spicer, Debra H. Josephs, Debra H. Josephs, Jenny L. Geh, Alastair MacKenzie Ross, Ciaran Healy, Sophie Papa, Katie E. Lacy, Sophia N. Karagiannis
Published 2019-03-01