Diminished Sphingolipid Metabolism, a Hallmark of Future Type 2 Diabetes Pathogenesis, Is Linked to Pancreatic β Cell Dysfunction

by Saifur R. Khan, Yousef Manialawy, Andreea Obersterescu, Brian J. Cox, Erica P. Gunderson, Michael B. Wheeler
Published 2020-10-01

Zip4 mediated zinc influx stimulates insulin secretion in pancreatic beta cells.

by Alexandre B Hardy, Kacey J Prentice, Sean Froese, Ying Liu, Glen K Andrews, Michael B Wheeler
Published 2015-01-01

Underlying dyslipidemia postpartum in women with a recent GDM pregnancy who develop type 2 diabetes

by Mi Lai, Dana Al Rijjal, Hannes L Röst, Feihan F Dai, Erica P Gunderson, Michael B Wheeler
Published 2020-08-01

An Abbreviated Protocol for In Vitro Generation of Functional Human Embryonic Stem Cell-Derived Beta-Like Cells.

by Mohammad Massumi, Farzaneh Pourasgari, Amarnadh Nalla, Battsetseg Batchuluun, Kristina Nagy, Eric Neely, Rida Gull, Andras Nagy, Michael B Wheeler
Published 2016-01-01

Early overnutrition in male mice negates metabolic benefits of a diet high in monounsaturated and omega-3 fats

by Maria M. Glavas, Queenie Hui, Ian Miao, Fan Yang, Suheda Erener, Kacey J. Prentice, Michael B. Wheeler, Timothy J. Kieffer
Published 2021-07-01

Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice

by Nivedita Seshadri, Michael E. Jonasson, Kristin L. Hunt, Bo Xiang, Steven Cooper, Michael B. Wheeler, Vernon W. Dolinsky, Christine A. Doucette
Published 2017-07-01

Correction: A Novel High-Throughput Assay for Islet Respiration Reveals Uncoupling of Rodent and Human Islets

by Jakob D. Wikstrom, Samuel B. Sereda, Linsey Stiles, Alvaro Elorza, Emma M. Allister, Andy Neilson, David A. Ferrick, Michael B. Wheeler, Orian S. Shirihai
Published 2013-01-01

Correction: A Novel High-Throughput Assay for Islet Respiration Reveals Uncoupling of Rodent and Human Islets.

by Jakob D. Wikstrom, Samuel B. Sereda, Linsey Stiles, Alvaro Elorza, Emma M. Allister, Andy Neilson, David A. Ferrick, Michael B. Wheeler, Orian S. Shirihai
Published 2013-01-01

A novel high-throughput assay for islet respiration reveals uncoupling of rodent and human islets.

by Jakob D Wikstrom, Samuel B Sereda, Linsey Stiles, Alvaro Elorza, Emma M Allister, Andy Neilson, David A Ferrick, Michael B Wheeler, Orian S Shirihai
Published 2012-01-01

RGS4-Deficiency Alters Intracellular Calcium and PKA-Mediated Control of Insulin Secretion in Glucose-Stimulated Beta Islets

by Guillaume Bastin, Lemieux Luu, Battsetseg Batchuluun, Alexandra Mighiu, Stephanie Beadman, Hangjung Zhang, Changhao He, Dana Al Rijjal, Michael B. Wheeler, Scott P. Heximer
Published 2021-08-01

Amino acid and lipid metabolism in post-gestational diabetes and progression to type 2 diabetes: A metabolic profiling study.

by Mi Lai, Ying Liu, Gabriele V Ronnett, Anne Wu, Brian J Cox, Feihan F Dai, Hannes L Röst, Erica P Gunderson, Michael B Wheeler
Published 2020-05-01

The Identification of Novel Protein-Protein Interactions in Liver that Affect Glucagon Receptor Activity.

by Junfeng Han, Ming Zhang, Sean Froese, Feihan F Dai, Mélanie Robitaille, Alpana Bhattacharjee, Xinyi Huang, Weiping Jia, Stéphane Angers, Michael B Wheeler, Li Wei
Published 2015-01-01

Intensive lactation among women with recent gestational diabetes significantly alters the early postpartum circulating lipid profile: the SWIFT study

by Ziyi Zhang, Mi Lai, Anthony L. Piro, Stacey E. Alexeeff, Amina Allalou, Hannes L. Röst, Feihan F. Dai, Michael B. Wheeler, Erica P. Gunderson
Published 2021-10-01

Correction: A Novel Humanized GLP-1 Receptor Model Enables Both Affinity Purification and Cre-LoxP Deletion of the Receptor.

by Lucy S Jun, Aaron D Showalter, Nosher Ali, Feihan Dai, Wenzhen Ma, Tamer Coskun, James V Ficorilli, Michael B Wheeler, M Dodson Michael, Kyle W Sloop
Published 2015-01-01

A novel humanized GLP-1 receptor model enables both affinity purification and Cre-LoxP deletion of the receptor.

by Lucy S Jun, Aaron D Showalter, Nosher Ali, Feihan Dai, Wenzhen Ma, Tamer Coskun, James V Ficorilli, Michael B Wheeler, M Dodson Michael, Kyle W Sloop
Published 2014-01-01

Vascepa protects against high-fat diet-induced glucose intolerance, insulin resistance, and impaired β-cell function

by Dana Al Rijjal, Ying Liu, Mi Lai, Youchen Song, Zahra Danaei, Anne Wu, Haneesha Mohan, Li Wei, Francisco J. Schopfer, Feihan F. Dai, Michael B. Wheeler
Published 2021-08-01

Rapid Elevation in CMPF May Act As a Tipping Point in Diabetes Development

by Ying Liu, Kacey J. Prentice, Judith A. Eversley, Cheng Hu, Battsetseg Batchuluun, Katherine Leavey, Jakob B. Hansen, David W. Wei, Brian Cox, Feihan F. Dai, Weiping Jia, Michael B. Wheeler
Published 2016-03-01

CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis

by Kacey J. Prentice, Stacy G. Wendell, Ying Liu, Judith A. Eversley, Sonia R. Salvatore, Haneesha Mohan, Sydney L. Brandt, Andrew C. Adams, X. Serena Wang, David Wei, Garret A. FitzGerald, Timothy B. Durham, Craig D. Hammond, Kyle W. Sloop, Carsten Skarke, Francisco J. Schopfer, Michael B. Wheeler
Published 2018-01-01