Role of a novel PH-kinase domain interface in PKB/Akt regulation: structural mechanism for allosteric inhibition.

by Véronique Calleja, Michel Laguerre, Peter J Parker, Banafshé Larijani
Published 2009-01-01

PKCɛ switches Aurora B specificity to exit the abscission checkpoint

by Tanya Pike, Nicola Brownlow, Svend Kjaer, Jeremy Carlton, Peter J. Parker
Published 2016-12-01

PKCα and PKCδ regulate ADAM17-mediated ectodomain shedding of heparin binding-EGF through separate pathways.

by Marie Kveiborg, Rachael Instrell, Christina Rowlands, Michael Howell, Peter J Parker
Published 2011-02-01

HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells.

by Anthony Kong, Véronique Calleja, Pierre Leboucher, Adrian Harris, Peter J Parker, Banafshé Larijani
Published 2008-08-01

HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer.

by Merel Gijsen, Peter King, Tim Perera, Peter J Parker, Adrian L Harris, Banafshé Larijani, Anthony Kong
Published 2010-12-01

Correction: HER2 Phosphorylation Is Maintained by a PKB Negative Feedback Loop in Response to Anti-HER2 Herceptin in Breast Cancer.

by Merel Gijsen, Peter King, Tim Perera, Peter J Parker, Adrian L Harris, Banafshé Larijani, Anthony Kong
Published 2016-03-01

Regulatory domain selectivity in the cell-type specific PKN-dependence of cell migration.

by Sylvie Lachmann, Amy Jevons, Manu De Rycker, Adele Casamassima, Simone Radtke, Alejandra Collazos, Peter J Parker
Published 2011-01-01

An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation.

by Carine Rosse, Etienne Formstecher, Katrina Boeckeler, Yingming Zhao, Joachim Kremerskothen, Michael D White, Jacques H Camonis, Peter J Parker
Published 2009-11-01

Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo.

by Véronique Calleja, Damien Alcor, Michel Laguerre, Jongsun Park, Borivoj Vojnovic, Brian A Hemmings, Julian Downward, Peter J Parker, Banafshé Larijani
Published 2007-04-01

A global sampler of single particle tracking solutions for single molecule microscopy.

by Michael Hirsch, Richard Wareham, Ji W Yoon, Daniel J Rolfe, Laura C Zanetti-Domingues, Michael P Hobson, Peter J Parker, Marisa L Martin-Fernandez, Sumeetpal S Singh
Published 2019-01-01

The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition

by Joanna R. Kelly, Silvia Martini, Nicola Brownlow, Dhira Joshi, Stefania Federico, Shirin Jamshidi, Svend Kjaer, Nicola Lockwood, Khondaker Miraz Rahman, Franca Fraternali, Peter J. Parker, Tanya N. Soliman
Published 2020-03-01

Author Correction: The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition

by Joanna R. Kelly, Silvia Martini, Nicola Brownlow, Dhira Joshi, Stefania Federico, Shirin Jamshidi, Svend Kjaer, Nicola Lockwood, Khondaker Miraz Rahman, Franca Fraternali, Peter J. Parker, Tanya N. Soliman
Published 2020-06-01

Correction: Corrigendum: Beta 1-integrin–c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes

by Rachel Barrow-McGee, Naoki Kishi, Carine Joffre, Ludovic Ménard, Alexia Hervieu, Bakhouche A. Bakhouche, Alejandro J. Noval, Anja Mai, Camilo Guzmán, Luisa Robbez-Masson, Xavier Iturrioz, James Hulit, Caroline H. Brennan, Ian R. Hart, Peter J. Parker, Johanna Ivaska, Stéphanie Kermorgant
Published 2016-07-01

Beta 1-integrin–c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes

by Rachel Barrow-McGee, Naoki Kishi, Carine Joffre, Ludovic Ménard, Alexia Hervieu, Bakhouche A. Bakhouche, Alejandro J. Noval, Anja Mai, Camilo Guzmán, Luisa Robbez-Masson, Xavier Iturrioz, James Hulit, Caroline H. Brennan, Ian R. Hart, Peter J. Parker, Johanna Ivaska, Stéphanie Kermorgant
Published 2016-06-01

Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion

by Ivan Quétier, Jacqueline J.T. Marshall, Bradley Spencer-Dene, Sylvie Lachmann, Adele Casamassima, Claudio Franco, Sarah Escuin, Joseph T. Worrall, Priththivika Baskaran, Vinothini Rajeeve, Michael Howell, Andrew J. Copp, Gordon Stamp, Ian Rosewell, Pedro Cutillas, Holger Gerhardt, Peter J. Parker, Angus J.M. Cameron
Published 2016-01-01

Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface

by Jeroen Claus, Gargi Patel, Flavia Autore, Audrey Colomba, Gregory Weitsman, Tanya N Soliman, Selene Roberts, Laura C Zanetti-Domingues, Michael Hirsch, Francesca Collu, Roger George, Elena Ortiz-Zapater, Paul R Barber, Boris Vojnovic, Yosef Yarden, Marisa L Martin-Fernandez, Angus Cameron, Franca Fraternali, Tony Ng, Peter J Parker
Published 2018-05-01

EGFR oligomerization organizes kinase-active dimers into competent signalling platforms

by Sarah R. Needham, Selene K. Roberts, Anton Arkhipov, Venkatesh P. Mysore, Christopher J. Tynan, Laura C. Zanetti-Domingues, Eric T. Kim, Valeria Losasso, Dimitrios Korovesis, Michael Hirsch, Daniel J. Rolfe, David T. Clarke, Martyn D. Winn, Alireza Lajevardipour, Andrew H. A. Clayton, Linda J. Pike, Michela Perani, Peter J. Parker, Yibing Shan, David E. Shaw, Marisa L. Martin-Fernandez
Published 2016-10-01

The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers

by Laura C. Zanetti-Domingues, Dimitrios Korovesis, Sarah R. Needham, Christopher J. Tynan, Shiori Sagawa, Selene K. Roberts, Antonija Kuzmanic, Elena Ortiz-Zapater, Purvi Jain, Rob C. Roovers, Alireza Lajevardipour, Paul M. P. van Bergen en Henegouwen, George Santis, Andrew H. A. Clayton, David T. Clarke, Francesco L. Gervasio, Yibing Shan, David E. Shaw, Daniel J. Rolfe, Peter J. Parker, Marisa L. Martin-Fernandez
Published 2018-10-01