Genomic regression analysis of coordinated expression

by Ling Cai, Qiwei Li, Yi Du, Jonghyun Yun, Yang Xie, Ralph J. DeBerardinis, Guanghua Xiao
Published 2017-12-01

Assessment of Rapid Hepatic Glycogen Synthesis in Humans Using Dynamic 13C Magnetic Resonance Spectroscopy

by Stefan Stender, Vlad G. Zaha, Craig R. Malloy, Jessica Sudderth, Ralph J. DeBerardinis, Jae Mo Park
Published 2020-03-01

Lkb1 deficiency confers glutamine dependency in polycystic kidney disease

by Ebony M. Flowers, Jessica Sudderth, Lauren Zacharias, Glenda Mernaugh, Roy Zent, Ralph J. DeBerardinis, Thomas J. Carroll
Published 2018-02-01

A Mitochondrial RNAi Screen Defines Cellular Bioenergetic Determinants and Identifies an Adenylate Kinase as a Key Regulator of ATP Levels

by Nathan J. Lanning, Brendan D. Looyenga, Audra L. Kauffman, Natalie M. Niemi, Jessica Sudderth, Ralph J. DeBerardinis, Jeffrey P. MacKeigan
Published 2014-05-01

Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis.

by Takla Griss, Emma E Vincent, Robert Egnatchik, Jocelyn Chen, Eric H Ma, Brandon Faubert, Benoit Viollet, Ralph J DeBerardinis, Russell G Jones
Published 2015-12-01

Systematic Analysis of Gene Expression in Lung Adenocarcinoma and Squamous Cell Carcinoma with a Case Study of <i>FAM83A</i> and <i>FAM83B</i>

by Ling Cai, Danni Luo, Bo Yao, Donghan M. Yang, ShinYi Lin, Luc Girard, Ralph J. DeBerardinis, John D. Minna, Yang Xie, Guanghua Xiao
Published 2019-06-01

Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation

by Yi-Heng Hao, M. Carmen Lafita-Navarro, Lauren Zacharias, Nofit Borenstein-Auerbach, Min Kim, Spencer Barnes, Jiwoong Kim, Jerry Shay, Ralph J. DeBerardinis, Maralice Conacci-Sorrell
Published 2019-10-01

Glutamine uptake and utilization of human mesenchymal glioblastoma in orthotopic mouse model

by Kristell Oizel, Chendong Yang, Ophelie Renoult, Fabien Gautier, Quyen N. Do, Noemie Joalland, Xiaofei Gao, Bookyung Ko, François Vallette, Woo-Ping Ge, François Paris, Ralph J. DeBerardinis, Claire Pecqueur
Published 2020-08-01

Oxidation of Alpha-Ketoglutarate Is Required for Reductive Carboxylation in Cancer Cells with Mitochondrial Defects

by Andrew R. Mullen, Zeping Hu, Xiaolei Shi, Lei Jiang, Lindsey K. Boroughs, Zoltan Kovacs, Richard Boriack, Dinesh Rakheja, Lucas B. Sullivan, W. Marston Linehan, Navdeep S. Chandel, Ralph J. DeBerardinis
Published 2014-06-01

MCT4 Defines a Glycolytic Subtype of Pancreatic Cancer with Poor Prognosis and Unique Metabolic Dependencies

by GuemHee Baek, Yan F. Tse, Zeping Hu, Derek Cox, Noah Buboltz, Peter McCue, Charles J. Yeo, Michael A. White, Ralph J. DeBerardinis, Erik S. Knudsen, Agnieszka K. Witkiewicz
Published 2014-12-01

Erratum: Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma

by Ugur Eskiocak, Vijayashree Ramesh, Jennifer G. Gill, Zhiyu Zhao, Stacy W. Yuan, Meng Wang, Travis Vandergriff, Mark Shackleton, Elsa Quintana, Arthur E. Frankel, Timothy M. Johnson, Ralph J. DeBerardinis, Sean J. Morrison
Published 2016-09-01

Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma

by Ugur Eskiocak, Vijayashree Ramesh, Jennifer G. Gill, Zhiyu Zhao, Stacy W. Yuan, Meng Wang, Travis Vandergriff, Mark Shackleton, Elsa Quintana, Arthur E. Frankel, Timothy M. Johnson, Ralph J. DeBerardinis, Sean J. Morrison
Published 2016-08-01

Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism

by Barrett L. Updegraff, Xiaorong Zhou, Yabin Guo, Mahesh S. Padanad, Pei-Hsuan Chen, Chendong Yang, Jessica Sudderth, Carla Rodriguez-Tirado, Luc Girard, John D. Minna, Prashant Mishra, Ralph J. DeBerardinis, Kathryn A. O’Donnell
Published 2018-11-01

Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer

by Alba Luengo, Keene L. Abbott, Shawn M. Davidson, Aaron M. Hosios, Brandon Faubert, Sze Ham Chan, Elizaveta Freinkman, Lauren G. Zacharias, Thomas P. Mathews, Clary B. Clish, Ralph J. DeBerardinis, Caroline A. Lewis, Matthew G. Vander Heiden
Published 2019-12-01

Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research

by John Kurhanewicz, Daniel B. Vigneron, Kevin Brindle, Eduard Y. Chekmenev, Arnaud Comment, Charles H. Cunningham, Ralph J. DeBerardinis, Gary G. Green, Martin O. Leach, Sunder S. Rajan, Rahim R. Rizi, Brian D. Ross, Warren S. Warren, Craig R. Malloy
Published 2011-02-01

Using arterial–venous analysis to characterize cancer metabolic consumption in patients

by Nanxiang Xiong, Xiaofei Gao, Hongyang Zhao, Feng Cai, Fang-cheng Zhang, Ye Yuan, Weichao Liu, Fangping He, Lauren G. Zacharias, Hong Lin, Hieu S. Vu, Chao Xing, Dong-Xiao Yao, Fei Chen, Benyan Luo, Wenzhi Sun, Ralph J. DeBerardinis, Hao Xu, Woo-ping Ge
Published 2020-06-01

Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis

by Mahesh S. Padanad, Georgia Konstantinidou, Niranjan Venkateswaran, Margherita Melegari, Smita Rindhe, Matthew Mitsche, Chendong Yang, Kimberly Batten, Kenneth E. Huffman, Jingwen Liu, Ximing Tang, Jaime Rodriguez-Canales, Neda Kalhor, Jerry W. Shay, John D. Minna, Jeffrey McDonald, Ignacio I. Wistuba, Ralph J. DeBerardinis, Pier Paolo Scaglioni
Published 2016-08-01

Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity

by Lindsay DeVorkin, Nils Pavey, Gillian Carleton, Alexandra Comber, Cally Ho, Junghyun Lim, Erin McNamara, Haochu Huang, Paul Kim, Lauren G. Zacharias, Noboru Mizushima, Tatsuya Saitoh, Shizuo Akira, Wayne Beckham, Alireza Lorzadeh, Michelle Moksa, Qi Cao, Aditya Murthy, Martin Hirst, Ralph J. DeBerardinis, Julian J. Lum
Published 2019-04-01

Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria

by Sara M Nowinski, Ashley Solmonson, Scott F Rusin, J Alan Maschek, Claire L Bensard, Sarah Fogarty, Mi-Young Jeong, Sandra Lettlova, Jordan A Berg, Jeffrey T Morgan, Yeyun Ouyang, Bradley C Naylor, Joao A Paulo, Katsuhiko Funai, James E Cox, Steven P Gygi, Dennis R Winge, Ralph J DeBerardinis, Jared Rutter
Published 2020-08-01

Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans

by Min Ni, Ashley Solmonson, Chunxiao Pan, Chendong Yang, Dan Li, Ashley Notzon, Ling Cai, Gerardo Guevara, Lauren G. Zacharias, Brandon Faubert, Hieu S. Vu, Lei Jiang, Bookyung Ko, Noriko Merida Morales, Jimin Pei, Gonçalo Vale, Dinesh Rakheja, Nick V. Grishin, Jeffrey G. McDonald, Garrett K. Gotway, Markey C. McNutt, Juan M. Pascual, Ralph J. DeBerardinis
Published 2019-04-01