Epigenetic assays for chemical biology and drug discovery

by Sheraz Gul
Published 2017-04-01

Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics

by Massimiliano Runfola, Simona Sestito, Sheraz Gul, Grazia Chiellini, Simona Rapposelli
Published 2020-04-01

Intravenous Bone Marrow Mononuclear Cells Transplantation in Aged Mice Increases Transcription of Glucose Transporter 1 and Na+/K+-ATPase at Hippocampus Followed by Restored Neurol...

by Yukiko Takeuchi, Yuka Okinaka, Yuko Ogawa, Akie Kikuchi-Taura, Yosky Kataoka, Yosky Kataoka, Sheraz Gul, Sheraz Gul, Carsten Claussen, Carsten Claussen, Johannes Boltze, Johannes Boltze, Akihiko Taguchi
Published 2020-06-01

Marine Derived Hamacanthins as Lead for the Development of Novel PDGFRβ Protein Kinase Inhibitors

by Christian Peifer, Frank Totzke, Christoph Schaechtele, Sheraz Gul, Joachim Schlosser, Eugen Johannes, Boris Pinchuk
Published 2013-08-01

The Target Residence Time of Antihistamines Determines Their Antagonism of the G Protein-Coupled Histamine H1 Receptor

by Reggie Bosma, Gesa Witt, Lea A. I. Vaas, Ivana Josimovic, Philip Gribbon, Henry F. Vischer, Sheraz Gul, Rob Leurs
Published 2017-09-01

Optimisation and Validation of a High Throughput Screening Compatible Assay to Identify Inhibitors of the Plasma Membrane Calcium ATPase Pump - a Novel Therapeutic Target for Contr...

by Tamer M A Mohamed, Simon A Zakeri, Florence Baudoin, Markus Wolf, Delvac Oceandy, Elizabeth J Cartwright, Sheraz Gul, Ludwig Neyses
Published 2013-05-01

Design, Synthesis and Structure—Activity Relationships of a Phenotypic Small Library against Protozoan Infections

by Elisa Uliassi, Lorna Piazzi, Federica Belluti, Marcel Kaiser, Reto Brun, Sheraz Gul, Bernhard Ellinger, Carolina B. Moraes, Lucio H. Freitas-Junior, Chiara Borsari, Maria Paola Costi, Maria Laura Bolognesi
Published 2017-10-01

The role of structural defects in commercial lithium-ion batteries

by Guannan Qian, Federico Monaco, Dechao Meng, Sang-Jun Lee, Guibin Zan, Jizhou Li, Dmitry Karpov, Sheraz Gul, David Vine, Benjamin Stripe, Jin Zhang, Jun-Sik Lee, Zi-Feng Ma, Wenbin Yun, Piero Pianetta, Xiqian Yu, Linsen Li, Peter Cloeten, Yijin Liu
Published 2021-09-01

Design, Synthesis and Antiparasitic Evaluation of Click Phospholipids

by George E. Magoulas, Pantelis Afroudakis, Kalliopi Georgikopoulou, Marina Roussaki, Chiara Borsari, Theano Fotopoulou, Nuno Santarem, Emile Barrias, Paloma Tejera Nevado, Julia Hachenberg, Eugenia Bifeld, Bernhard Ellinger, Maria Kuzikov, Irini Fragiadaki, Effie Scoulica, Joachim Clos, Sheraz Gul, Maria Paola Costi, Wanderley de Souza, Kyriakos C. Prousis, Anabela Cordeiro da Silva, Theodora Calogeropoulou
Published 2021-07-01

A Drug Repositioning Approach Identifies a Combination of Compounds as a Potential Regimen for Chronic Lymphocytic Leukemia Treatment

by Atef Nehdi, Atef Nehdi, Atef Nehdi, Nosaibah Samman, Nosaibah Samman, Abdullah Mashhour, Abdullah Mashhour, Alshaimaa Alhallaj, Alshaimaa Alhallaj, Thadeo Trivilegio, Thadeo Trivilegio, Sheraz Gul, Jeanette Reinshagen, Ahmed Alaskar, Ahmed Alaskar, Ahmed Alaskar, Gamal Gmati, Gamal Gmati, Khadega A. Abuelgasim, Khadega A. Abuelgasim, Fatmah Mansour, Fatmah Mansour, Mohamed Boudjelal, Mohamed Boudjelal
Published 2021-05-01

KAIMRC’S Second Therapeutics Discovery Conference

by Zeyad Alehaideb, Nimer Mehyar, Mai Al Ajaji, Mohammed Alassiri, Manal Alaamery, Bader Al Debasi, Bandar Alghanem, Jahad Alghamdi, Bahauddeen M. Alrfaei, Barrak Al Somaie, Ahmed Bakillah, Tlili Barhoumi, Yosra Boudjelal, Ibrahim Bushnak, Majid Alfadhel, Sheraz Gul, Imadul Islam, Mo Li, Theam Soon Lim, Salam Massadeh, Lamis Mouyes, Adel Nefzi, Atef Nehdi, Wyatt Yue, Ahmed Alaskar, Mohamed Boudjelal
Published 2020-04-01

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

by Pasquale Linciano, Alice Dawson, Ina Pöhner, David M. Costa, Monica S. Sá, Anabela Cordeiro-da-Silva, Rosaria Luciani, Sheraz Gul, Gesa Witt, Bernhard Ellinger, Maria Kuzikov, Philip Gribbon, Jeanette Reinshagen, Markus Wolf, Birte Behrens, Véronique Hannaert, Paul A. M. Michels, Erika Nerini, Cecilia Pozzi, Flavio di Pisa, Giacomo Landi, Nuno Santarem, Stefania Ferrari, Puneet Saxena, Sandra Lazzari, Giuseppe Cannazza, Lucio H. Freitas-Junior, Carolina B. Moraes, Bruno S. Pascoalino, Laura M. Alcântara, Claudia P. Bertolacini, Vanessa Fontana, Ulrike Wittig, Wolfgang Müller, Rebecca C. Wade, William N. Hunter, Stefano Mangani, Luca Costantino, Maria P. Costi
Published 2017-09-01

Soft x-ray absorption spectroscopy of metalloproteins and high-valent metal-complexes at room temperature using free-electron lasers

by Markus Kubin, Jan Kern, Sheraz Gul, Thomas Kroll, Ruchira Chatterjee, Heike Löchel, Franklin D. Fuller, Raymond G. Sierra, Wilson Quevedo, Christian Weniger, Jens Rehanek, Anatoly Firsov, Hartawan Laksmono, Clemens Weninger, Roberto Alonso-Mori, Dennis L. Nordlund, Benedikt Lassalle-Kaiser, James M. Glownia, Jacek Krzywinski, Stefan Moeller, Joshua J. Turner, Michael P. Minitti, Georgi L. Dakovski, Sergey Koroidov, Anurag Kawde, Jacob S. Kanady, Emily Y. Tsui, Sandy Suseno, Zhiji Han, Ethan Hill, Taketo Taguchi, Andrew S. Borovik, Theodor Agapie, Johannes Messinger, Alexei Erko, Alexander Föhlisch, Uwe Bergmann, Rolf Mitzner, Vittal K. Yachandra, Junko Yano, Philippe Wernet
Published 2017-09-01