CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen Blastomyces dermatitidis

by Gregory C. Kujoth, Thomas D. Sullivan, Richard Merkhofer, Taek-Jin Lee, Huafeng Wang, Tristan Brandhorst, Marcel Wuthrich, Bruce S. Klein, Joseph Heitman
Published 2018-04-01

The elicitin-like glycoprotein, ELI025, is secreted by the pathogenic oomycete Pythium insidiosum and evades host antibody responses.

by Tassanee Lerksuthirat, Tassanee Lohnoo, Ruchuros Inkomlue, Thidarat Rujirawat, Wanta Yingyong, Rommanee Khositnithikul, Narumon Phaonakrop, Sittiruk Roytrakul, Thomas D Sullivan, Theerapong Krajaejun
Published 2015-01-01

SREB, a GATA transcription factor that directs disparate fates in Blastomyces dermatitidis including morphogenesis and siderophore biosynthesis.

by Gregory M Gauthier, Thomas D Sullivan, Sergio S Gallardo, T Tristan Brandhorst, Amber J Vanden Wymelenberg, Christina A Cuomo, Garret Suen, Cameron R Currie, Bruce S Klein
Published 2010-04-01

The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia.

by José F Muñoz, Gregory M Gauthier, Christopher A Desjardins, Juan E Gallo, Jason Holder, Thomas D Sullivan, Amber J Marty, John C Carmen, Zehua Chen, Li Ding, Sharvari Gujja, Vincent Magrini, Elizabeth Misas, Makedonka Mitreva, Margaret Priest, Sakina Saif, Emily A Whiston, Sarah Young, Qiandong Zeng, William E Goldman, Elaine R Mardis, John W Taylor, Juan G McEwen, Oliver K Clay, Bruce S Klein, Christina A Cuomo
Published 2015-10-01