Nephrotoxicity in a Patient With Inadequate Pain Control: Potential Role of Pharmacogenetic Testing for Cytochrome P450 2D6 and Apolipoprotein L1

by Emma M. Tillman, Todd C. Skaar, Michael T. Eadon
Published 2020-01-01

Carboplatin with Decitabine Therapy, in Recurrent Platinum Resistant Ovarian Cancer, Alters Circulating miRNAs Concentrations: A Pilot Study.

by Eric A Benson, Todd C Skaar, Yunlong Liu, Kenneth P Nephew, Daniela Matei
Published 2015-01-01

Variability of Dosing and Number of Medications Needed to Achieve Adequate Sedation in Mechanically Ventilated Pediatric Intensive Care Patients

by Emma M. Tillman, Joseph Ipe, Kelly J. Weaver, Todd C. Skaar, Courtney M. Rowan, James E. Slaven
Published 2021-01-01

Enrollment of Diverse Populations in the INGENIOUS Pharmacogenetics Clinical Trial

by Ebony Shah-Williams, Kenneth D. Levy, Yong Zang, Ann M. Holmes, Christa Stoughton, Paul Dexter, Paul Dexter, Todd C. Skaar
Published 2020-06-01

Allelic decomposition and exact genotyping of highly polymorphic and structurally variant genes

by Ibrahim Numanagić, Salem Malikić, Michael Ford, Xiang Qin, Lorraine Toji, Milan Radovich, Todd C. Skaar, Victoria M. Pratt, Bonnie Berger, Steve Scherer, S. Cenk Sahinalp
Published 2018-02-01

Tracheal Aspirate as an Alternative Biologic Sample for Pharmacogenomics Testing in Mechanically Ventilated Pediatric Patients

by Katherine A. Hargreaves, Victoria M. Pratt, Elizabeth B. Medeiros, Ty C. Lynnes, Caitlin A. Granfield, Todd C. Skaar, Aiko Iwata‐Otsubo, Emma M. Tillman
Published 2021-03-01

Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes

by Eric A Benson, Michael T Eadon, Zeruesenay eDesta, Yunlong eLiu, Hai eLin, Kimberly S Burgess, Matthew W Segar, Andrea eGaedigk, Todd C Skaar
Published 2016-04-01

PASSPORT-seq: A Novel High-Throughput Bioassay to Functionally Test Polymorphisms in Micro-RNA Target Sites

by Joseph Ipe, Kimberly S. Collins, Kimberly S. Collins, Yangyang Hao, Yangyang Hao, Hongyu Gao, Hongyu Gao, Puja Bhatia, Andrea Gaedigk, Yunlong Liu, Yunlong Liu, Todd C. Skaar
Published 2018-06-01

Whole genome amplification of DNA for genotyping pharmacogenetics candidate genes.

by Santosh ePhilips, James M Rae, Steffi eOesterreich, Daniel F Hayes, Vered eStearns, Norah Lynn Henry, Anna M Storniolo, David A Flockhart, Todd C Skaar
Published 2012-03-01

RegSNPs-intron: a computational framework for predicting pathogenic impact of intronic single nucleotide variants

by Hai Lin, Katherine A. Hargreaves, Rudong Li, Jill L. Reiter, Yue Wang, Matthew Mort, David N. Cooper, Yaoqi Zhou, Chi Zhang, Michael T. Eadon, M. Eileen Dolan, Joseph Ipe, Todd C. Skaar, Yunlong Liu
Published 2019-11-01

Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach

by Michael T. Eadon, Ronald J. Hause, Amy L. Stark, Ying-Hua Cheng, Heather E. Wheeler, Kimberly S. Burgess, Eric A. Benson, Patrick N. Cunningham, Robert L. Bacallao, Pierre C. Dagher, Todd C. Skaar, M. Eileen Dolan
Published 2017-03-01

Implementation of a Renal Precision Medicine Program: Clinician Attitudes and Acceptance

by Katherine M. Spiech, Purnima R. Tripathy, Alex M. Woodcock, Nehal A. Sheth, Kimberly S. Collins, Karthik Kannegolla, Arjun D. Sinha, Asif A. Sharfuddin, Victoria M. Pratt, Myda Khalid, David S. Hains, Sharon M. Moe, Todd C. Skaar, Ranjani N. Moorthi, Michael T. Eadon
Published 2020-03-01

Genome-wide discovery of drug-dependent human liver regulatory elements.

by Robin P Smith, Walter L Eckalbar, Kari M Morrissey, Marcelo R Luizon, Thomas J Hoffmann, Xuefeng Sun, Stacy L Jones, Shelley Force Aldred, Anuradha Ramamoorthy, Zeruesenay Desta, Yunlong Liu, Todd C Skaar, Nathan D Trinklein, Kathleen M Giacomini, Nadav Ahituv
Published 2014-10-01