Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

by Ploegh, Hidde, Smith, Melanie H., Weissman, Jonathan S.
Published 2014

A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation

by Rouskin, Silvi, Li, Gene-Wei, Weissman, Jonathan S.
Published 2020

Mammalian microRNAs predominantly act to decrease target mRNA levels

by Guo, Huili, Ingolia, Nicholas T., Weissman, Jonathan S., Bartel, David
Published 2012

Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo

by Rouskin, Silvi, Zubradt, Meghan, Washietl, Stefan, Kellis, Manolis, Weissman, Jonathan S.
Published 2016

Ribosome Profiling Provides Evidence that Large Noncoding RNAs Do Not Encode Proteins

by Guttman, Mitchell, Russell, Pamela, Ingolia, Nicholas T, Weissman, Jonathan S, Lander, Eric S, Lander, Eric Steven
Published 2016

High-Resolution View of the Yeast Meiotic Program Revealed by Ribosome Profiling

by Regev, Aviv, Brar, Gloria A., Yassour, Moran, Friedman, Nir, Ingolia, Nicholas T., Weissman, Jonathan S.
Published 2014

Operon mRNAs are organized into ORF-centric structures that predict translation efficiency

by Burkhardt, David H, Rouskin, Silvi, Zhang, Yan, Li, Gene-Wei, Weissman, Jonathan S, Gross, Carol A
Published 2018

Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation

by Horlbeck, Max A., Gilbert, Luke A., Weissman, Jonathan S., Bruno, Peter Michael, Hemann, Michael, Braun, Christian Joerg
Published 2018

Aneuploid yeast strains exhibit defects in cell growth and passage through START

by Thorburn, Rebecca Ruth, Gonzalez, Christian, Brar, Gloria A., Christen, Stefan, Carlile, Thomas M., Ingolia, Nicholas T., Sauer, Uwe, Weissman, Jonathan S., Amon, Angelika B
Published 2013

A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation

by Fields, Alexander P, Rodriguez, Edwin H, Jovanovic, Marko, Stern-Ginossar, Noam, Haas, Brian J, Mertins, Philipp, Raychowdhury, Raktima, Hacohen, Nir, Carr, Steven A, Ingolia, Nicholas T, Regev, Aviv, Weissman, Jonathan S
Published 2016

The helicase Ded1p controls use of near-cognate translation initiation codons in 5' UTRs

by Guenther, Ulf-Peter, Weinberg, David E., Zubradt, Meghan M., Tedeschi, Frank A., Stawicki, Brittany N., Zagore, Leah L., Brar, Gloria A., Licatalosi, Donny D., Bartel, David, Weissman, Jonathan S., Jankowsky, Eckhard
Published 2020

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

by Gilbert, Luke A, Horlbeck, Max A, Adamson, Britt, Villalta, Jacqueline E, Chen, Yuwen, Whitehead, Evan H, Guimaraes, Carla, Panning, Barbara, Bassik, Michael C, Qi, Lei S, Kampmann, Martin, Weissman, Jonathan S, Ploegh, Hidde
Published 2017

A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern

by Berchowitz, Luke Edwin, Gajadhar, Aaron, van Werven, Folkert J., De Rosa, Alexandra A., Samoylova, Mariya L., Brar, Gloria A., Xu, Yifeng, Xiao, Che, Futcher, Bruce, Weissman, Jonathan S., White, Forest M., Amon, Angelika B
Published 2014

Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

by Dixit, Atray, Parnas, Oren, Li, Biyu, Chen, Jenny, Fulco, Charles P., Jerby-Arnon, Livnat, Marjanovic, Nemanja D., Dionne, Danielle, Burks, Tyler, Raychowdhury, Raktima, Adamson, Britt, Norman, Thomas M., Weissman, Jonathan S., Friedman, Nir, Lander, Eric Steven, Regev, Aviv
Published 2018

Development of a set of C•G-to-G•C transversion base editors from CRISPRi screens, target-library analysis, and machine learning

by Koblan, Luke W., Arbab, Mandana, Shen, Max Walt, Hussmann, Jeffrey A., Anzalone, Andrew V., Doman, Jordan L, Newby, Gregory Arthur, Yang, Dian, Mok, Beverly, Replogle, Joseph M., Xu, Albert, Sisley, Tyler A., Weissman, Jonathan S., Adamson, Britt, Liu, David R.
Published 2021

Proto-genes and de novo gene birth

by Carvunis, Anne-Ruxandra, Rolland, Thomas, Wapinski, Ilan, Calderwood, Michael A., Yildirim, Muhammed A., Simonis, Nicolas, Charloteaux, Benoit, Barbette, Justin, Santhanam, Balaji, Brar, Gloria A., Weissman, Jonathan S., Regev, Aviv, Thierry-Mieg, Nicolas, Cusick, Michael E., Vidal, Marc, Hidalgo Ramaciotti, Cesar A.
Published 2013

A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

by Adamson, Britt, Norman, Thomas M., Jost, Marco, Cho, Min Y., Nuñez, James K., Chen, Yuwen, Villalta, Jacqueline E., Gilbert, Luke A., Horlbeck, Max A., Hein, Marco Y., Pak, Ryan A., Gray, Andrew N., Gross, Carol A., Parnas, Oren, Weissman, Jonathan S., Dixit, Atray C., Regev, Aviv
Published 2018

Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing

by Nuñez, James K, Chen, Jin, Pommier, Greg C, Cogan, J Zachery, Replogle, Joseph M, Adriaens, Carmen, Ramadoss, Gokul N, Shi, Quanming, Hung, King L, Samelson, Avi J, Pogson, Angela N, Kim, James YS, Chung, Amanda, Leonetti, Manuel D, Chang, Howard Y, Kampmann, Martin, Bernstein, Bradley E, Hovestadt, Volker, Gilbert, Luke A, Weissman, Jonathan S
Published 2022

The Human Cell Atlas

by Teichmann, Sarah A, Amit, Ido, Benoist, Christophe, Birney, Ewan, Bodenmiller, Bernd, Campbell, Peter, Carninci, Piero, Clatworthy, Menna, Clevers, Hans, Deplancke, Bart, Dunham, Ian, Eberwine, James, Eils, Roland, Enard, Wolfgang, Farmer, Andrew, Fugger, Lars, Göttgens, Berthold, Hacohen, Nir, Haniffa, Muzlifah, Hemberg, Martin, Kim, Seung, Klenerman, Paul, Kriegstein, Arnold, Lein, Ed, Linnarsson, Sten, Lundberg, Emma, Lundeberg, Joakim, Majumder, Partha, Marioni, John C, Merad, Miriam, Mhlanga, Musa, Nawijn, Martijn, Netea, Mihai, Nolan, Garry, Pe'er, Dana, Phillipakis, Anthony, Ponting, Chris P, Quake, Stephen, Reik, Wolf, Rozenblatt-Rosen, Orit, Sanes, Joshua, Satija, Rahul, Schumacher, Ton N, Shalek, Alex, Shapiro, Ehud, Sharma, Padmanee, Shin, Jay W, Stegle, Oliver, Stratton, Michael, Stubbington, Michael J T, Theis, Fabian J, Uhlen, Matthias, van Oudenaarden, Alexander, Wagner, Allon, Watt, Fiona, Weissman, Jonathan, Wold, Barbara, Xavier, Ramnik, Yosef, Nir, Regev, Aviv, Lander, Eric Steven
Published 2018