A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Past genome-wide associate studies have identified hundreds of genetic loci that influence body size and shape when examined one trait at a time. Here, Jeff and colleagues develop an aggregate score of various body traits, and use meta-analysis to find new loci linked to body shape.
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms13357 |
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DOAJ |
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English |
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author |
Janina S. Ried Janina Jeff M. Audrey Y. Chu Jennifer L. Bragg-Gresham Jenny van Dongen Jennifer E. Huffman Tarunveer S. Ahluwalia Gemma Cadby Niina Eklund Joel Eriksson Tõnu Esko Mary F. Feitosa Anuj Goel Mathias Gorski Caroline Hayward Nancy L. Heard-Costa Anne U. Jackson Eero Jokinen Stavroula Kanoni Kati Kristiansson Zoltán Kutalik Jari Lahti Jian'an Luan Reedik Mägi Anubha Mahajan Massimo Mangino Carolina Medina-Gomez Keri L. Monda Ilja M. Nolte Louis Pérusse Inga Prokopenko Lu Qi Lynda M. Rose Erika Salvi Megan T. Smith Harold Snieder Alena Stančáková Yun Ju Sung Ioanna Tachmazidou Alexander Teumer Gudmar Thorleifsson Pim van der Harst Ryan W. Walker Sophie R. Wang Sarah H. Wild Sara M. Willems Andrew Wong Weihua Zhang Eva Albrecht Alexessander Couto Alves Stephan J. L. Bakker Cristina Barlassina Traci M. Bartz John Beilby Claire Bellis Richard N. Bergman Sven Bergmann John Blangero Matthias Blüher Eric Boerwinkle Lori L. Bonnycastle Stefan R. Bornstein Marcel Bruinenberg Harry Campbell Yii-Der Ida Chen Charleston W. K. Chiang Peter S. Chines Francis S Collins Fracensco Cucca L Adrienne Cupples Francesca D’Avila Eco J .C. de Geus George Dedoussis Maria Dimitriou Angela Döring Johan G. Eriksson Aliki-Eleni Farmaki Martin Farrall Teresa Ferreira Krista Fischer Nita G. Forouhi Nele Friedrich Anette Prior Gjesing Nicola Glorioso Mariaelisa Graff Harald Grallert Niels Grarup Jürgen Gräßler Jagvir Grewal Anders Hamsten Marie Neergaard Harder Catharina A. Hartman Maija Hassinen Nicholas Hastie Andrew Tym Hattersley Aki S. Havulinna Markku Heliövaara Hans Hillege Albert Hofman Oddgeir Holmen Georg Homuth Jouke-Jan Hottenga Jennie Hui Lise Lotte Husemoen Pirro G. Hysi Aaron Isaacs Till Ittermann Shapour Jalilzadeh Alan L. James Torben Jørgensen Pekka Jousilahti Antti Jula Johanne Marie Justesen Anne E. Justice Mika Kähönen Maria Karaleftheri Kay Tee Khaw Sirkka M. Keinanen-Kiukaanniemi Leena Kinnunen Paul B. Knekt Heikki A. Koistinen Ivana Kolcic Ishminder K. Kooner Seppo Koskinen Peter Kovacs Theodosios Kyriakou Tomi Laitinen Claudia Langenberg Alexandra M. Lewin Peter Lichtner Cecilia M. Lindgren Jaana Lindström Allan Linneberg Roberto Lorbeer Mattias Lorentzon Robert Luben Valeriya Lyssenko Satu Männistö Paolo Manunta Irene Mateo Leach Wendy L. McArdle Barbara Mcknight Karen L. Mohlke Evelin Mihailov Lili Milani Rebecca Mills May E. Montasser Andrew P. Morris Gabriele Müller Arthur W. Musk Narisu Narisu Ken K. Ong Ben A. Oostra Clive Osmond Aarno Palotie James S. Pankow Lavinia Paternoster Brenda W. Penninx Irene Pichler Maria G. Pilia Ozren Polašek Peter P. Pramstaller Olli T Raitakari Tuomo Rankinen D. C. Rao Nigel W. Rayner Rasmus Ribel-Madsen Treva K. Rice Marcus Richards Paul M. Ridker Fernando Rivadeneira Kathy A. Ryan Serena Sanna Mark A. Sarzynski Salome Scholtens Robert A. Scott Sylvain Sebert Lorraine Southam Thomas Hempel Sparsø Valgerdur Steinthorsdottir Kathleen Stirrups Ronald P. Stolk Konstantin Strauch Heather M. Stringham Morris A. Swertz Amy J. Swift Anke Tönjes Emmanouil Tsafantakis Peter J. van der Most Jana V. Van Vliet-Ostaptchouk Liesbeth Vandenput Erkki Vartiainen Cristina Venturini Niek Verweij Jorma S. Viikari Veronique Vitart Marie-Claude Vohl Judith M. Vonk Gérard Waeber Elisabeth Widén Gonneke Willemsen Tom Wilsgaard Thomas W. Winkler Alan F. Wright Laura M. Yerges-Armstrong Jing Hua Zhao M. Carola Zillikens Dorret I. Boomsma Claude Bouchard John C. Chambers Daniel I. Chasman Daniele Cusi Ron T. Gansevoort Christian Gieger Torben Hansen Andrew A. Hicks Frank Hu Kristian Hveem Marjo-Riitta Jarvelin Eero Kajantie Jaspal S. Kooner Diana Kuh Johanna Kuusisto Markku Laakso Timo A. Lakka Terho Lehtimäki Andres Metspalu Inger Njølstad Claes Ohlsson Albertine J. Oldehinkel Lyle J. Palmer Oluf Pedersen Markus Perola Annette Peters Bruce M. Psaty Hannu Puolijoki Rainer Rauramaa Igor Rudan Veikko Salomaa Peter E. H. Schwarz Alan R. Shudiner Jan H. Smit Thorkild I. A. Sørensen Timothy D. Spector Kari Stefansson Michael Stumvoll Angelo Tremblay Jaakko Tuomilehto André G. Uitterlinden Matti Uusitupa Uwe Völker Peter Vollenweider Nicholas J. Wareham Hugh Watkins James F. Wilson Eleftheria Zeggini Goncalo R. Abecasis Michael Boehnke Ingrid B. Borecki Panos Deloukas Cornelia M. van Duijn Caroline Fox Leif C. Groop Iris M. Heid David J. Hunter Robert C. Kaplan Mark I. McCarthy Kari E. North Jeffrey R. O'Connell David Schlessinger Unnur Thorsteinsdottir David P. Strachan Timothy Frayling Joel N. Hirschhorn Martina Müller-Nurasyid Ruth J. F. Loos |
spellingShingle |
Janina S. Ried Janina Jeff M. Audrey Y. Chu Jennifer L. Bragg-Gresham Jenny van Dongen Jennifer E. Huffman Tarunveer S. Ahluwalia Gemma Cadby Niina Eklund Joel Eriksson Tõnu Esko Mary F. Feitosa Anuj Goel Mathias Gorski Caroline Hayward Nancy L. Heard-Costa Anne U. Jackson Eero Jokinen Stavroula Kanoni Kati Kristiansson Zoltán Kutalik Jari Lahti Jian'an Luan Reedik Mägi Anubha Mahajan Massimo Mangino Carolina Medina-Gomez Keri L. Monda Ilja M. Nolte Louis Pérusse Inga Prokopenko Lu Qi Lynda M. Rose Erika Salvi Megan T. Smith Harold Snieder Alena Stančáková Yun Ju Sung Ioanna Tachmazidou Alexander Teumer Gudmar Thorleifsson Pim van der Harst Ryan W. Walker Sophie R. Wang Sarah H. Wild Sara M. Willems Andrew Wong Weihua Zhang Eva Albrecht Alexessander Couto Alves Stephan J. L. Bakker Cristina Barlassina Traci M. Bartz John Beilby Claire Bellis Richard N. Bergman Sven Bergmann John Blangero Matthias Blüher Eric Boerwinkle Lori L. Bonnycastle Stefan R. Bornstein Marcel Bruinenberg Harry Campbell Yii-Der Ida Chen Charleston W. K. Chiang Peter S. Chines Francis S Collins Fracensco Cucca L Adrienne Cupples Francesca D’Avila Eco J .C. de Geus George Dedoussis Maria Dimitriou Angela Döring Johan G. Eriksson Aliki-Eleni Farmaki Martin Farrall Teresa Ferreira Krista Fischer Nita G. Forouhi Nele Friedrich Anette Prior Gjesing Nicola Glorioso Mariaelisa Graff Harald Grallert Niels Grarup Jürgen Gräßler Jagvir Grewal Anders Hamsten Marie Neergaard Harder Catharina A. Hartman Maija Hassinen Nicholas Hastie Andrew Tym Hattersley Aki S. Havulinna Markku Heliövaara Hans Hillege Albert Hofman Oddgeir Holmen Georg Homuth Jouke-Jan Hottenga Jennie Hui Lise Lotte Husemoen Pirro G. Hysi Aaron Isaacs Till Ittermann Shapour Jalilzadeh Alan L. James Torben Jørgensen Pekka Jousilahti Antti Jula Johanne Marie Justesen Anne E. Justice Mika Kähönen Maria Karaleftheri Kay Tee Khaw Sirkka M. Keinanen-Kiukaanniemi Leena Kinnunen Paul B. Knekt Heikki A. Koistinen Ivana Kolcic Ishminder K. Kooner Seppo Koskinen Peter Kovacs Theodosios Kyriakou Tomi Laitinen Claudia Langenberg Alexandra M. Lewin Peter Lichtner Cecilia M. Lindgren Jaana Lindström Allan Linneberg Roberto Lorbeer Mattias Lorentzon Robert Luben Valeriya Lyssenko Satu Männistö Paolo Manunta Irene Mateo Leach Wendy L. McArdle Barbara Mcknight Karen L. Mohlke Evelin Mihailov Lili Milani Rebecca Mills May E. Montasser Andrew P. Morris Gabriele Müller Arthur W. Musk Narisu Narisu Ken K. Ong Ben A. Oostra Clive Osmond Aarno Palotie James S. Pankow Lavinia Paternoster Brenda W. Penninx Irene Pichler Maria G. Pilia Ozren Polašek Peter P. Pramstaller Olli T Raitakari Tuomo Rankinen D. C. Rao Nigel W. Rayner Rasmus Ribel-Madsen Treva K. Rice Marcus Richards Paul M. Ridker Fernando Rivadeneira Kathy A. Ryan Serena Sanna Mark A. Sarzynski Salome Scholtens Robert A. Scott Sylvain Sebert Lorraine Southam Thomas Hempel Sparsø Valgerdur Steinthorsdottir Kathleen Stirrups Ronald P. Stolk Konstantin Strauch Heather M. Stringham Morris A. Swertz Amy J. Swift Anke Tönjes Emmanouil Tsafantakis Peter J. van der Most Jana V. Van Vliet-Ostaptchouk Liesbeth Vandenput Erkki Vartiainen Cristina Venturini Niek Verweij Jorma S. Viikari Veronique Vitart Marie-Claude Vohl Judith M. Vonk Gérard Waeber Elisabeth Widén Gonneke Willemsen Tom Wilsgaard Thomas W. Winkler Alan F. Wright Laura M. Yerges-Armstrong Jing Hua Zhao M. Carola Zillikens Dorret I. Boomsma Claude Bouchard John C. Chambers Daniel I. Chasman Daniele Cusi Ron T. Gansevoort Christian Gieger Torben Hansen Andrew A. Hicks Frank Hu Kristian Hveem Marjo-Riitta Jarvelin Eero Kajantie Jaspal S. Kooner Diana Kuh Johanna Kuusisto Markku Laakso Timo A. Lakka Terho Lehtimäki Andres Metspalu Inger Njølstad Claes Ohlsson Albertine J. Oldehinkel Lyle J. Palmer Oluf Pedersen Markus Perola Annette Peters Bruce M. Psaty Hannu Puolijoki Rainer Rauramaa Igor Rudan Veikko Salomaa Peter E. H. Schwarz Alan R. Shudiner Jan H. Smit Thorkild I. A. Sørensen Timothy D. Spector Kari Stefansson Michael Stumvoll Angelo Tremblay Jaakko Tuomilehto André G. Uitterlinden Matti Uusitupa Uwe Völker Peter Vollenweider Nicholas J. Wareham Hugh Watkins James F. Wilson Eleftheria Zeggini Goncalo R. Abecasis Michael Boehnke Ingrid B. Borecki Panos Deloukas Cornelia M. van Duijn Caroline Fox Leif C. Groop Iris M. Heid David J. Hunter Robert C. Kaplan Mark I. McCarthy Kari E. North Jeffrey R. O'Connell David Schlessinger Unnur Thorsteinsdottir David P. Strachan Timothy Frayling Joel N. Hirschhorn Martina Müller-Nurasyid Ruth J. F. Loos A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape Nature Communications |
author_facet |
Janina S. Ried Janina Jeff M. Audrey Y. Chu Jennifer L. Bragg-Gresham Jenny van Dongen Jennifer E. Huffman Tarunveer S. Ahluwalia Gemma Cadby Niina Eklund Joel Eriksson Tõnu Esko Mary F. Feitosa Anuj Goel Mathias Gorski Caroline Hayward Nancy L. Heard-Costa Anne U. Jackson Eero Jokinen Stavroula Kanoni Kati Kristiansson Zoltán Kutalik Jari Lahti Jian'an Luan Reedik Mägi Anubha Mahajan Massimo Mangino Carolina Medina-Gomez Keri L. Monda Ilja M. Nolte Louis Pérusse Inga Prokopenko Lu Qi Lynda M. Rose Erika Salvi Megan T. Smith Harold Snieder Alena Stančáková Yun Ju Sung Ioanna Tachmazidou Alexander Teumer Gudmar Thorleifsson Pim van der Harst Ryan W. Walker Sophie R. Wang Sarah H. Wild Sara M. Willems Andrew Wong Weihua Zhang Eva Albrecht Alexessander Couto Alves Stephan J. L. Bakker Cristina Barlassina Traci M. Bartz John Beilby Claire Bellis Richard N. Bergman Sven Bergmann John Blangero Matthias Blüher Eric Boerwinkle Lori L. Bonnycastle Stefan R. Bornstein Marcel Bruinenberg Harry Campbell Yii-Der Ida Chen Charleston W. K. Chiang Peter S. Chines Francis S Collins Fracensco Cucca L Adrienne Cupples Francesca D’Avila Eco J .C. de Geus George Dedoussis Maria Dimitriou Angela Döring Johan G. Eriksson Aliki-Eleni Farmaki Martin Farrall Teresa Ferreira Krista Fischer Nita G. Forouhi Nele Friedrich Anette Prior Gjesing Nicola Glorioso Mariaelisa Graff Harald Grallert Niels Grarup Jürgen Gräßler Jagvir Grewal Anders Hamsten Marie Neergaard Harder Catharina A. Hartman Maija Hassinen Nicholas Hastie Andrew Tym Hattersley Aki S. Havulinna Markku Heliövaara Hans Hillege Albert Hofman Oddgeir Holmen Georg Homuth Jouke-Jan Hottenga Jennie Hui Lise Lotte Husemoen Pirro G. Hysi Aaron Isaacs Till Ittermann Shapour Jalilzadeh Alan L. James Torben Jørgensen Pekka Jousilahti Antti Jula Johanne Marie Justesen Anne E. Justice Mika Kähönen Maria Karaleftheri Kay Tee Khaw Sirkka M. Keinanen-Kiukaanniemi Leena Kinnunen Paul B. Knekt Heikki A. Koistinen Ivana Kolcic Ishminder K. Kooner Seppo Koskinen Peter Kovacs Theodosios Kyriakou Tomi Laitinen Claudia Langenberg Alexandra M. Lewin Peter Lichtner Cecilia M. Lindgren Jaana Lindström Allan Linneberg Roberto Lorbeer Mattias Lorentzon Robert Luben Valeriya Lyssenko Satu Männistö Paolo Manunta Irene Mateo Leach Wendy L. McArdle Barbara Mcknight Karen L. Mohlke Evelin Mihailov Lili Milani Rebecca Mills May E. Montasser Andrew P. Morris Gabriele Müller Arthur W. Musk Narisu Narisu Ken K. Ong Ben A. Oostra Clive Osmond Aarno Palotie James S. Pankow Lavinia Paternoster Brenda W. Penninx Irene Pichler Maria G. Pilia Ozren Polašek Peter P. Pramstaller Olli T Raitakari Tuomo Rankinen D. C. Rao Nigel W. Rayner Rasmus Ribel-Madsen Treva K. Rice Marcus Richards Paul M. Ridker Fernando Rivadeneira Kathy A. Ryan Serena Sanna Mark A. Sarzynski Salome Scholtens Robert A. Scott Sylvain Sebert Lorraine Southam Thomas Hempel Sparsø Valgerdur Steinthorsdottir Kathleen Stirrups Ronald P. Stolk Konstantin Strauch Heather M. Stringham Morris A. Swertz Amy J. Swift Anke Tönjes Emmanouil Tsafantakis Peter J. van der Most Jana V. Van Vliet-Ostaptchouk Liesbeth Vandenput Erkki Vartiainen Cristina Venturini Niek Verweij Jorma S. Viikari Veronique Vitart Marie-Claude Vohl Judith M. Vonk Gérard Waeber Elisabeth Widén Gonneke Willemsen Tom Wilsgaard Thomas W. Winkler Alan F. Wright Laura M. Yerges-Armstrong Jing Hua Zhao M. Carola Zillikens Dorret I. Boomsma Claude Bouchard John C. Chambers Daniel I. Chasman Daniele Cusi Ron T. Gansevoort Christian Gieger Torben Hansen Andrew A. Hicks Frank Hu Kristian Hveem Marjo-Riitta Jarvelin Eero Kajantie Jaspal S. Kooner Diana Kuh Johanna Kuusisto Markku Laakso Timo A. Lakka Terho Lehtimäki Andres Metspalu Inger Njølstad Claes Ohlsson Albertine J. Oldehinkel Lyle J. Palmer Oluf Pedersen Markus Perola Annette Peters Bruce M. Psaty Hannu Puolijoki Rainer Rauramaa Igor Rudan Veikko Salomaa Peter E. H. Schwarz Alan R. Shudiner Jan H. Smit Thorkild I. A. Sørensen Timothy D. Spector Kari Stefansson Michael Stumvoll Angelo Tremblay Jaakko Tuomilehto André G. Uitterlinden Matti Uusitupa Uwe Völker Peter Vollenweider Nicholas J. Wareham Hugh Watkins James F. Wilson Eleftheria Zeggini Goncalo R. Abecasis Michael Boehnke Ingrid B. Borecki Panos Deloukas Cornelia M. van Duijn Caroline Fox Leif C. Groop Iris M. Heid David J. Hunter Robert C. Kaplan Mark I. McCarthy Kari E. North Jeffrey R. O'Connell David Schlessinger Unnur Thorsteinsdottir David P. Strachan Timothy Frayling Joel N. Hirschhorn Martina Müller-Nurasyid Ruth J. F. Loos |
author_sort |
Janina S. Ried |
title |
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape |
title_short |
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape |
title_full |
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape |
title_fullStr |
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape |
title_full_unstemmed |
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape |
title_sort |
principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2016-11-01 |
description |
Past genome-wide associate studies have identified hundreds of genetic loci that influence body size and shape when examined one trait at a time. Here, Jeff and colleagues develop an aggregate score of various body traits, and use meta-analysis to find new loci linked to body shape. |
url |
https://doi.org/10.1038/ncomms13357 |
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principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT leenakinnunen principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT paulbknekt principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT heikkiakoistinen principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT ivanakolcic principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT ishminderkkooner principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT seppokoskinen principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT peterkovacs principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT theodosioskyriakou principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT tomilaitinen principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT claudialangenberg principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT alexandramlewin principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT peterlichtner principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT ceciliamlindgren principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT jaanalindstrom principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT allanlinneberg principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT robertolorbeer principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT mattiaslorentzon principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT robertluben 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principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT davidpstrachan principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT timothyfrayling principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT joelnhirschhorn principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT martinamullernurasyid principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape AT ruthjfloos principalcomponentmetaanalysisonmultipleanthropometrictraitsidentifiesnovellociforbodyshape |
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doaj-f36bd59969d44358bd7caf32e2240b932021-05-11T11:14:11ZengNature Publishing GroupNature Communications2041-17232016-11-017111110.1038/ncomms13357A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shapeJanina S. Ried0Janina Jeff M.1Audrey Y. Chu2Jennifer L. Bragg-Gresham3Jenny van Dongen4Jennifer E. Huffman5Tarunveer S. Ahluwalia6Gemma Cadby7Niina Eklund8Joel Eriksson9Tõnu Esko10Mary F. Feitosa11Anuj Goel12Mathias Gorski13Caroline Hayward14Nancy L. Heard-Costa15Anne U. Jackson16Eero Jokinen17Stavroula Kanoni18Kati Kristiansson19Zoltán Kutalik20Jari Lahti21Jian'an Luan22Reedik Mägi23Anubha Mahajan24Massimo Mangino25Carolina Medina-Gomez26Keri L. Monda27Ilja M. Nolte28Louis Pérusse29Inga Prokopenko30Lu Qi31Lynda M. Rose32Erika Salvi33Megan T. Smith34Harold Snieder35Alena Stančáková36Yun Ju Sung37Ioanna Tachmazidou38Alexander Teumer39Gudmar Thorleifsson40Pim van der Harst41Ryan W. Walker42Sophie R. Wang43Sarah H. Wild44Sara M. Willems45Andrew Wong46Weihua Zhang47Eva Albrecht48Alexessander Couto Alves49Stephan J. L. Bakker50Cristina Barlassina51Traci M. Bartz52John Beilby53Claire Bellis54Richard N. Bergman55Sven Bergmann56John Blangero57Matthias Blüher58Eric Boerwinkle59Lori L. Bonnycastle60Stefan R. Bornstein61Marcel Bruinenberg62Harry Campbell63Yii-Der Ida Chen64Charleston W. K. Chiang65Peter S. Chines66Francis S Collins67Fracensco Cucca68L Adrienne Cupples69Francesca D’Avila70Eco J .C. de Geus71George Dedoussis72Maria Dimitriou73Angela Döring74Johan G. Eriksson75Aliki-Eleni Farmaki76Martin Farrall77Teresa Ferreira78Krista Fischer79Nita G. Forouhi80Nele Friedrich81Anette Prior Gjesing82Nicola Glorioso83Mariaelisa Graff84Harald Grallert85Niels Grarup86Jürgen Gräßler87Jagvir Grewal88Anders Hamsten89Marie Neergaard Harder90Catharina A. Hartman91Maija Hassinen92Nicholas Hastie93Andrew Tym Hattersley94Aki S. Havulinna95Markku Heliövaara96Hans Hillege97Albert Hofman98Oddgeir Holmen99Georg Homuth100Jouke-Jan Hottenga101Jennie Hui102Lise Lotte Husemoen103Pirro G. Hysi104Aaron Isaacs105Till Ittermann106Shapour Jalilzadeh107Alan L. James108Torben Jørgensen109Pekka Jousilahti110Antti Jula111Johanne Marie Justesen112Anne E. Justice113Mika Kähönen114Maria Karaleftheri115Kay Tee Khaw116Sirkka M. Keinanen-Kiukaanniemi117Leena Kinnunen118Paul B. Knekt119Heikki A. Koistinen120Ivana Kolcic121Ishminder K. Kooner122Seppo Koskinen123Peter Kovacs124Theodosios Kyriakou125Tomi Laitinen126Claudia Langenberg127Alexandra M. Lewin128Peter Lichtner129Cecilia M. Lindgren130Jaana Lindström131Allan Linneberg132Roberto Lorbeer133Mattias Lorentzon134Robert Luben135Valeriya Lyssenko136Satu Männistö137Paolo Manunta138Irene Mateo Leach139Wendy L. McArdle140Barbara Mcknight141Karen L. Mohlke142Evelin Mihailov143Lili Milani144Rebecca Mills145May E. Montasser146Andrew P. Morris147Gabriele Müller148Arthur W. Musk149Narisu Narisu150Ken K. Ong151Ben A. Oostra152Clive Osmond153Aarno Palotie154James S. Pankow155Lavinia Paternoster156Brenda W. Penninx157Irene Pichler158Maria G. Pilia159Ozren Polašek160Peter P. Pramstaller161Olli T Raitakari162Tuomo Rankinen163D. C. Rao164Nigel W. Rayner165Rasmus Ribel-Madsen166Treva K. Rice167Marcus Richards168Paul M. Ridker169Fernando Rivadeneira170Kathy A. Ryan171Serena Sanna172Mark A. Sarzynski173Salome Scholtens174Robert A. Scott175Sylvain Sebert176Lorraine Southam177Thomas Hempel Sparsø178Valgerdur Steinthorsdottir179Kathleen Stirrups180Ronald P. Stolk181Konstantin Strauch182Heather M. Stringham183Morris A. Swertz184Amy J. Swift185Anke Tönjes186Emmanouil Tsafantakis187Peter J. van der Most188Jana V. Van Vliet-Ostaptchouk189Liesbeth Vandenput190Erkki Vartiainen191Cristina Venturini192Niek Verweij193Jorma S. Viikari194Veronique Vitart195Marie-Claude Vohl196Judith M. Vonk197Gérard Waeber198Elisabeth Widén199Gonneke Willemsen200Tom Wilsgaard201Thomas W. Winkler202Alan F. Wright203Laura M. Yerges-Armstrong204Jing Hua Zhao205M. Carola Zillikens206Dorret I. Boomsma207Claude Bouchard208John C. Chambers209Daniel I. Chasman210Daniele Cusi211Ron T. Gansevoort212Christian Gieger213Torben Hansen214Andrew A. Hicks215Frank Hu216Kristian Hveem217Marjo-Riitta Jarvelin218Eero Kajantie219Jaspal S. Kooner220Diana Kuh221Johanna Kuusisto222Markku Laakso223Timo A. Lakka224Terho Lehtimäki225Andres Metspalu226Inger Njølstad227Claes Ohlsson228Albertine J. Oldehinkel229Lyle J. Palmer230Oluf Pedersen231Markus Perola232Annette Peters233Bruce M. Psaty234Hannu Puolijoki235Rainer Rauramaa236Igor Rudan237Veikko Salomaa238Peter E. H. Schwarz239Alan R. Shudiner240Jan H. Smit241Thorkild I. A. Sørensen242Timothy D. Spector243Kari Stefansson244Michael Stumvoll245Angelo Tremblay246Jaakko Tuomilehto247André G. Uitterlinden248Matti Uusitupa249Uwe Völker250Peter Vollenweider251Nicholas J. Wareham252Hugh Watkins253James F. Wilson254Eleftheria Zeggini255Goncalo R. Abecasis256Michael Boehnke257Ingrid B. Borecki258Panos Deloukas259Cornelia M. van Duijn260Caroline Fox261Leif C. Groop262Iris M. Heid263David J. Hunter264Robert C. Kaplan265Mark I. McCarthy266Kari E. North267Jeffrey R. O'Connell268David Schlessinger269Unnur Thorsteinsdottir270David P. Strachan271Timothy Frayling272Joel N. Hirschhorn273Martina Müller-Nurasyid274Ruth J. F. Loos275Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental HealthThe Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount SinaiDivision of Preventive Medicine, Brigham and Women's HospitalKidney Epidemiology and Cost Center, Internal Medicine-Nephrology, University of MichiganDepartment of Biological Psychology, VU UniversityMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of EdinburghFaculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of CopenhagenCentre for Genetic Origins of Health and Disease, University of Western AustraliaDepartment of Health, National Institute for Health and Welfare (THL)Department of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of GothenburgBroad Institute of the Massachusetts Institute of Technology and Harvard UniversityDivision of Statistical Genomics, Department of Genetics, Washington University School of MedicineDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of OxfordDepartment of Nephrology, University Hospital RegensburgMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of EdinburghNational Heart, Lung, and Blood Institute, the Framingham Heart StudyDepartment of Biostatistics, Center for Statistical Genetics, University of MichiganHospital for Children and Adolescents, University of HelsinkiWellcome Trust Sanger Institute, Human GeneticsDepartment of Health, National Institute for Health and Welfare (THL)Swiss Institute of BioinformaticsFolkhälsan Research CentreMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical CampusEstonian Genome Center, University of TartuWellcome Trust Centre for Human Genetics, University of OxfordDepartment of Twin Research and Genetic Epidemiology, King's College LondonDepartment of Epidemiology, Erasmus Medical CenterDepartment of Epidemiology, University of North Carolina at Chapel HillDepartment of Epidemiology, University of Groningen, University Medical Center GroningenDepartment of Kinesiology, Laval UniversityWellcome Trust Centre for Human Genetics, University of OxfordDepartment of Medicine, Channing Division of Network Medicine, Brigham and Women’s Hospital and Harvard Medical SchoolDivision of Preventive Medicine, Brigham and Women's HospitalDepartment of Health Sciences, University of Milano at San Paolo HospitalDepartment of Biostatistics, University of WashingtonDepartment of Epidemiology, University of Groningen, University Medical Center GroningenDepartment of Medicine, University of Eastern Finland and Kuopio University HospitalDivision of Biostatistics, Washington University School of MedicineWellcome Trust Sanger Institute, Human GeneticsInstitute for Community Medicine, University Medicine GreifswalddeCODE Genetics, Amgen inc.Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart InstituteThe Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount SinaiDepartment of Genetics, Harvard Medical SchoolCentre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of EdinburghDepartment of Epidemiology, Genetic Epidemiology Unit, Erasmus University Medical CenterMRC Unit for Lifelong Health & Ageing at UCLDepartment of Epidemiology and Biostatistics, Imperial College LondonInstitute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental HealthDepartment of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial CollegeDepartment of Medicine, University of Groningen, University Medical Center GroningenDepartment of Health Sciences, University of Milano at San Paolo HospitalDepartment of Biostatistics, University of WashingtonPathwest Laboratory Medicine of Western AustraliaGenomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of TechnologyDiabetes and Obesity Research Institute, Cedars-Sinai Medical CenterSwiss Institute of BioinformaticsSouth Texas Diabetes and Obesity Institute, University of Texas Rio Grande ValleyUniversity of Leipzig, IFB Adiposity DiseasesHuman Genetics Center and Institute of Molecular Medicine, University of Texas Health Science CenterMedical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIHDepartment of Medicine III, Medical Faculty Carl Gustav Carus, University of DresdenUniversity of Groningen, University Medical Center Groningen, The LifeLines Cohort StudyCentre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of EdinburghLos Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical CenterDepartment of Psychiatry, University of CaliforniaMedical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIHMedical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIHUniversity of SassariNational Heart, Lung, and Blood Institute, the Framingham Heart StudyDepartment of Health Sciences, University of Milano at San Paolo HospitalDepartment of Biological Psychology, VU UniversityDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio UniversityWellcome Trust Sanger Institute, Human GeneticsInstitute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental HealthFolkhälsan Research CentreDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio UniversityDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of OxfordWellcome Trust Centre for Human Genetics, University of OxfordEstonian Genome Center, University of TartuMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical CampusInstitute of Clinical Chemistry and Laboratory Medicine, University Medicine GreifswaldFaculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of CopenhagenHypertension and Related Disease Centre, AOU-University of SassariDepartment of Epidemiology, University of North Carolina at Chapel HillInstitute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental HealthFaculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of CopenhagenDepartment of Medicine III, Pathobiochemistry, Technische UniversitaetDepartment of Epidemiology and Biostatistics, Imperial College LondonDepartment of Medicine, Karolinska InstitutetFaculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of CopenhagenUniversity of Groningen, University Medical Center Groningen, Interdisciplinary Center Psychopathology and Emotion RegulationKuopio Research Institute of Exercise MedicineMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of EdinburghInstitue of Biomedical & Clinical Science, University of Exeter, Barrack Road, Exeter EX2 5DW, UKDepartment of Health, National Institute for Health and Welfare (THL)Department of Health, National Institute for Health and Welfare (THL)Department of Cardiology, University of Groningen, University Medical Center GroningenDepartment of Epidemiology, Erasmus Medical CenterDepartment of Public Health and General Practice, Norwegian University of Science and TechnologyInterfaculty Institute for Genetics and Functional Genomics, University Medicine GreifswaldDepartment of Biological Psychology, VU UniversityPathwest Laboratory Medicine of Western AustraliaResearch Centre for Prevention and Health, Glostrup HospitalDepartment of Twin Research and Genetic Epidemiology, King's College LondonDepartment of Epidemiology, Genetic Epidemiology Unit, Erasmus University Medical CenterInstitute for Community Medicine, University Medicine GreifswaldDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of OxfordDepartment of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner HospitalDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of CopenhagenDepartment of Health, National Institute for Health and Welfare (THL)Department of Health, National Institute for Health and Welfare (THL)Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of CopenhagenDepartment of Epidemiology, University of North Carolina at Chapel HillDepartment of Clinical Physiology, Tampere University HospitalEchinos Medical CentreClinical Gerontology Unit, Box 251, Addenbrooke's Hospital, Hills RoadFaculty of Medicine, Institute of Health Sciences, University of OuluNational Institute for Health and WelfareDepartment of Health, National Institute for Health and Welfare (THL)National Institute for Health and WelfareDepartment of Public Health, Faculty of Medicine, University of SplitEaling Hospital NHS TrustDepartment of Health, National Institute for Health and Welfare (THL)University of Leipzig, IFB Adiposity DiseasesDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of OxfordKuopio University HospitalMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical CampusDepartment of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial CollegeInstitute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental HealthBroad Institute of the Massachusetts Institute of Technology and Harvard UniversityDepartment of Health, National Institute for Health and Welfare (THL)Research Centre for Prevention and Health, Glostrup HospitalInstitute for Community Medicine, University Medicine GreifswaldDepartment of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of GothenburgStrangeways Research Laboratory Wort's CausewaySteno Diabetes Center A/SDepartment of Health, National Institute for Health and Welfare (THL)Chair of Nephrology, Università Vita Salute San Raffaele and Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific InstituteDepartment of Cardiology, University of Groningen, University Medical Center GroningenSchool of Social and Community Medicine, University of BristolDepartment of Biostatistics, University of WashingtonDepartment of Genetics, University of North CarolinaEstonian Genome Center, University of TartuEstonian Genome Center, University of TartuEaling Hospital NHS TrustDivision of Endocrinology, Department of Medicine, Diabetes & Nutrition, Program for Personalized and Genomic Medicine, University of Maryland School of MedicineWellcome Trust Centre for Human Genetics, University of OxfordCenter for Evidence Based Healthcare, University of Dresden, Medical Faculty Carl Gustav CarusDepartment of Respiratory Medicine, Sir Charles Gairdner HospitalMedical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIHMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical CampusDepartment of Epidemiology, Genetic Epidemiology Unit, Erasmus University Medical CenterMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General HospitalInstitute for Molecular Medicine Finland, University of HelsinkiDivision of Epidemiology and Community Health, School of Public Health, University of MinnesotaMRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of BristolDepartment of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical CenterCenter for Biomedicine, European Academy Bozen/Bolzano (EURAC)Istituto di Ricerca Genetica e Biomedica, CNRCentre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of EdinburghCenter for Biomedicine, European Academy Bozen/Bolzano (EURAC)Department of Clinical Physiology and Nuclear Medicine, Turku University HospitalHuman Genomics Laboratory, Pennington Biomedical Research CenterDivision of Biostatistics, Washington University School of MedicineWellcome Trust Centre for Human Genetics, University of OxfordFaculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of CopenhagenDivision of Biostatistics, Washington University School of MedicineOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill HospitalDivision of Preventive Medicine, Brigham and Women's HospitalDepartment of Epidemiology, Erasmus Medical CenterDivision of Endocrinology, Department of Medicine, Diabetes & Nutrition, Program for Personalized and Genomic Medicine, University of Maryland School of MedicineIstituto di Ricerca Genetica e Biomedica, CNRHuman Genomics Laboratory, Pennington Biomedical Research CenterDepartment of Epidemiology, University of Groningen, University Medical Center GroningenMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical CampusDepartment of Genomics of Common Disease, School of Public Health, Imperial College LondonWellcome Trust Centre for Human Genetics, University of OxfordFaculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of CopenhagendeCODE Genetics, Amgen inc.Wellcome Trust Sanger Institute, Human GeneticsDepartment of Epidemiology, University of Groningen, University Medical Center GroningenInstitute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental HealthDepartment of Biostatistics, Center for Statistical Genetics, University of MichiganDepartment of Genetics, University of Groningen, University Medical Center GroningenMedical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIHDepartment of Medicine, University of LeipzigAnogia Medical CentreDepartment of Epidemiology, University of Groningen, University Medical Center GroningenDepartment of Endocrinology, University of Groningen, University Medical Center GroningenDepartment of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of GothenburgDepartment of Health, National Institute for Health and Welfare (THL)Department of Twin Research and Genetic Epidemiology, King's College LondonDepartment of Cardiology, University of Groningen, University Medical Center GroningenDepartment of Medicine, University of TurkuMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of EdinburghInstitute of Nutrition and Functional Foods, Laval UniversityDepartment of Epidemiology, University of Groningen, University Medical Center GroningenDepartment of Internal Medicine, University Hospital Lausanne (CHUV) and University of LausanneInstitute for Molecular Medicine Finland, University of HelsinkiDepartment of Biological Psychology, VU UniversityDepartment of Community Medicine, Faculty of Health Sciences, University of TromsøDepartment of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of RegensburgMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of EdinburghDivision of Endocrinology, Department of Medicine, Diabetes & Nutrition, Program for Personalized and Genomic Medicine, University of Maryland School of MedicineMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical CampusDepartment of Internal Medicine, Erasmus Medical CenterDepartment of Biological Psychology, VU UniversityHuman Genomics Laboratory, Pennington Biomedical Research CenterDepartment of Epidemiology and Biostatistics, Imperial College LondonDivision of Preventive Medicine, Brigham and Women's HospitalDepartment of Health Sciences, University of Milano at San Paolo HospitalDepartment of Medicine, University of Groningen, University Medical Center GroningenInstitute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental HealthFaculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of CopenhagenCenter for Biomedicine, European Academy Bozen/Bolzano (EURAC)Department of Medicine, Channing Division of Network Medicine, Brigham and Women’s Hospital and Harvard Medical SchoolDepartment of Public Health and General Practice, Norwegian University of Science and TechnologyBiocenter Oulu, University of OuluDepartment of Health, National Institute for Health and Welfare (THL)Ealing Hospital NHS TrustMRC Unit for Lifelong Health & Ageing at UCLDepartment of Medicine, University of Eastern Finland and Kuopio University HospitalDepartment of Medicine, University of Eastern Finland and Kuopio University HospitalKuopio Research Institute of Exercise MedicineDepartment of Clinical Chemistry, University of Tampere School of MedicineEstonian Genome Center, University of TartuDepartment of Community Medicine, Faculty of Health Sciences, University of TromsøDepartment of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of GothenburgUniversity of Groningen, University Medical Center Groningen, Interdisciplinary Center Psychopathology and Emotion RegulationSchool of Public Health, University of AdelaideFaculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of CopenhagenDepartment of Health, National Institute for Health and Welfare (THL)Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental HealthCardiovascular Health Research Unit, University of WashingtonSouth Ostrobothnia Central HospitalKuopio Research Institute of Exercise MedicineCentre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of EdinburghDepartment of Health, National Institute for Health and Welfare (THL)Department of Medicine III, Medical Faculty Carl Gustav Carus, University of DresdenDivision of Endocrinology, Department of Medicine, Diabetes & Nutrition, Program for Personalized and Genomic Medicine, University of Maryland School of MedicineDepartment of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical CenterFaculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of CopenhagenDepartment of Twin Research and Genetic Epidemiology, King's College LondondeCODE Genetics, Amgen inc.University of Leipzig, IFB Adiposity DiseasesDepartment of Kinesiology, Laval UniversityDiabetes Prevention Unit, National Institute for Health and WelfareDepartment of Epidemiology, Erasmus Medical CenterDepartment of Public Health and Clinical Nutrition, University of Eastern FinlandInterfaculty Institute for Genetics and Functional Genomics, University Medicine GreifswaldDepartment of Internal Medicine, University Hospital Lausanne (CHUV) and University of LausanneMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical CampusDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of OxfordMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of EdinburghWellcome Trust Sanger Institute, Human GeneticsDepartment of Biostatistics, Center for Statistical Genetics, University of MichiganDepartment of Biostatistics, Center for Statistical Genetics, University of MichiganDivision of Statistical Genomics, Department of Genetics, Washington University School of MedicineWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of LondonDepartment of Epidemiology, Genetic Epidemiology Unit, Erasmus University Medical CenterNational Heart, Lung, and Blood Institute, the Framingham Heart StudyLund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund UniversityDepartment of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of RegensburgBroad Institute of the Massachusetts Institute of Technology and Harvard UniversityDepartment of Epidemiology and Popualtion Health, Albert Einstein College of MedicineWellcome Trust Centre for Human Genetics, University of OxfordDepartment of Epidemiology, Carolina Center for Genome Sciences, University of North Carolina at Chapel HillDivision of Endocrinology, Department of Medicine, Diabetes & Nutrition, Program for Personalized and Genomic Medicine, University of Maryland School of MedicineNational Institute on Aging, National Institutes of HealthdeCODE Genetics, Amgen inc.Population Health Research Institute, St George's, University of LondonGenetics of Complex Traits, University of Exeter Medical School, University of ExeterBroad Institute of the Massachusetts Institute of Technology and Harvard UniversityInstitute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental HealthThe Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount SinaiPast genome-wide associate studies have identified hundreds of genetic loci that influence body size and shape when examined one trait at a time. Here, Jeff and colleagues develop an aggregate score of various body traits, and use meta-analysis to find new loci linked to body shape.https://doi.org/10.1038/ncomms13357 |