MYC regulation of a "poor-prognosis" metastatic cancer cell state

MYC regulation of a "poor-prognosis" metastatic cancer cell state

Gene expression signatures are used in the clinic as prognostic tools to determine the risk of individual patients with localized breast tumors developing distant metastasis. We lack a clear understanding, however, of whether these correlative biomarkers link to a common biological network that regu...

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Main Authors: Mesirov, Jill P. (Contributor), Wolfer, Anita (Author), Wittner, Ben S. (Author), Irimia, Daniel (Author), Flavin, Richard J. (Author), Lupien, Mathieu (Author), Gunawardane, Ruwanthi N. (Author), Meyer, Clifford A. (Author), Lightcap, Eric S. (Author), Tamayo, Pablo (Author), Liu, X. Shirley (Author), Shioda, Toshi (Author), Toner, Mehmet (Author), Loda, Massimo (Author), Brown, Myles (Author), Brugge, Joan S. (Author), Ramaswamy, Sridhar (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2014-03-28T19:10:41Z.
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