Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells

Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells

Differentiation of human embryonic stem cells (hESCs) provides a unique opportunity to study the regulatory mechanisms that facilitate cellular transitions in a human context. To that end, we performed comprehensive transcriptional and epigenetic profiling of populations derived through directed dif...

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Main Authors: Gifford, Casey A (Author), Ziller, Michael J (Author), Gu, Hongcang (Author), Trapnell, Cole (Author), Donaghey, Julie (Author), Tsankov, Alexander (Author), Shalek, Alex K. (Author), Kelley, David R (Author), Shishkin, Alexander A (Author), Issner, Robbyn (Author), Zhang, Xiaolan (Author), Coyne, Michael J. (Author), Fostel, Jennifer L. (Author), Holmes, Laurie (Author), Meldrim, James C. (Author), Guttman, Mitchell (Author), Epstein, Charles B. (Author), Park, Hongkun (Author), Kohlbacher, Oliver (Author), Rinn, John L. (Author), Gnirke, Andreas (Author), Bernstein, Bradley E. (Author), Meissner, Alexander (Author), Lander, Eric Steven (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Lander, Eric S. (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2014-06-04T19:03:41Z.
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