Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

by Yu, Yimin, Israelsen, William James, Mattaini, Katherine Ruth, Fiske, Brian Prescott, Malstrom, Scott E., Khan, Tahsin M., Lunt, Sophia Yunkyungkwon, Johnson, Zachary, Davidson, Shawn Michael, Vander Heiden, Matthew G., Jha, Abhishek K., Stephano, Gregory
Published 2013

Global Transcriptional and Translational Repression in Human-Embryonic-Stem-Cell-Derived Rett Syndrome Neurons

by Li, Yun, Wang, Haoyi, Muffat, Julien, Cheng, Albert W, Orlando, David A., Feldman, Danielle A, Bateup, Helen S, Gao, Qing, Hockemeyer, Dirk, Mitalipova, Maisam, Lewis, Caroline A, Sur, Mriganka, Young, Richard A, Jaenisch, Rudolf, Loven, Jakob, Vander Heiden, Matthew G., Feldman, Danielle A., Young, Richard A., Lewis, Caroline, Kwok, Show Ming
Published 2016

Metformin Decreases Glucose Oxidation and Increases the Dependency of Prostate Cancer Cells on Reductive Glutamine Metabolism

by Fendt, Sarah-Maria, Bell, Eric L., Keibler, Mark Andrew, Davidson, Shawn Michael, Wirth, Gregory J., Fiske, Brian Prescott, Mayers, Jared R., Schwab, Matthias, Bellinger, Gary, Csibi, Alfred, Patnaik, Akash, Blouin, Marie Jose, Cantley, Lewis C., Guarente, Leonard Pershing, Blenis, John, Pollak, Michael N., Olumi, Aria F., Vander Heiden, Matthew G., Stephanopoulos, Gregory
Published 2014

Acetate metabolism in cancer cells

by Hosios, Aaron M, Vander Heiden, Matthew G.
Published 2014

An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation

by Kini, Mitali, Mattaini, Katherine Ruth, Davidson, Shawn Michael, Fiske, Brian Prescott, Vander Heiden, Matthew G., Brignole, Edward J, Drennan, Catherine L
Published 2015

Understanding the Intersections between Metabolism and Cancer Biology

by Vander Heiden, Matthew G., DeBerardinis, Ralph J.
Published 2018

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance

by Kami, Kenjiro, Shelton, Laura M., Ramkissoon, Shakti H., Ligon, Keith L., Snuderl, Matija, Kim, Dohoon, Fiske, Brian Prescott, Birsoy, Kivanc, Freinkman, Elizaveta, Possemato, Richard, Chudnovsky, Yakov, Chen, Walter W., Cantor, Jason R., Gui, Dan Yi, Kwon, ManJae, Kang, Seong Woo, Vander Heiden, Matthew G., Sabatini, David, Pacold, Michael Edward
Published 2017

Biochemical Underpinnings of Immune Cell Metabolic Phenotypes

by Olenchock, Benjamin A., Rathmell, Jeffrey C., Vander Heiden, Matthew G.
Published 2018

Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy

by Luengo, Alba, Sullivan, Lucas Bryan, Vander Heiden, Matthew G.
Published 2014

Famine versus feast: understanding the metabolism of tumors in vivo

by Vander Heiden, Matthew G., Mayers, Jared R.
Published 2016

Understanding Metabolic Regulation and Its Influence on Cell Physiology

by Metallo, Christian M., Vander Heiden, Matthew G
Published 2014

The importance of serine metabolism in cancer

by Mattaini, Katherine Ruth, Sullivan, Mark Robert, Vander Heiden, Matthew G.
Published 2017

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

by Vander Heiden, Matthew G.
Published 2018

Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy

by Vander Heiden, Matthew G.
Published 2014

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

by Vander Heiden, Matthew G., Lunt, Sophia Yunkyungkwon
Published 2013

Pyruvate kinase: Function, regulation and role in cancer

by Israelsen, William James, Vander Heiden, Matthew G.
Published 2016

Deficiency of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis

by Alkan, H. Furkan, Vesely, Paul W, Hackl, Hubert, Foßelteder, Johannes, Schmidt, Daniel, Vander Heiden, Matthew G., Pichler, Martin, Hoefler, Gerald, Bogner-Strauss, Juliane G
Published 2022

Circadian Rhythm Disruption Promotes Lung Tumorigenesis

by Papagiannakopoulos, Thales, Bauer, Matthew R., Davidson, Shawn M., Heimann, Megan Kristianne, Subbaraj, Lakshmipriya, Bhutkar, Arjun, Bartlebaugh, Jordan M. E., Vander Heiden, Matthew G., Jacks, Tyler E.
Published 2018

Cell-State-Specific Metabolic Dependency in Hematopoiesis and Leukemogenesis

by Wang, Ying-Hua, Lee, Dongjun, Yu, Vionnie W.C, Jeanson, Nathaniel T, Clish, Clary B, Cantley, Lewis C, Scadden, David T, Israelsen, William James, Vander Heiden, Matthew G.
Published 2016

Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer

by Sayin, Volkan I, LeBoeuf, Sarah E, Singh, Simranjit X, Biancur, Douglas, Guzelhan, Betul S, Alvarez, Samantha W, Wu, Warren L, Karakousi, Triantafyllia R, Zavitsanou, Anastasia Maria, Ubriaco, Julian, Karagiannis, Dimitris, Morris, Patrick J, Thomas, Craig J, Possemato, Richard, Papagiannakopoulos, Thales, Davidson, Shawn M, Muir, Alexander, Vander Heiden, Matthew G.
Published 2018