Molecular mechanism for direct actin force-sensing by α-catenin

by Lin Mei, Santiago Espinosa de los Reyes, Matthew J Reynolds, Rachel Leicher, Shixin Liu, Gregory M Alushin
Published 2020-09-01

Global mapping of miRNA-target interactions in cattle (Bos taurus)

by Troels K. H. Scheel, Michael J. Moore, Joseph M. Luna, Eiko Nishiuchi, John Fak, Robert B. Darnell, Charles M. Rice
Published 2017-08-01

The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs

by Aitor Garzia, Seyed Mehdi Jafarnejad, Cindy Meyer, Clément Chapat, Tasos Gogakos, Pavel Morozov, Mehdi Amiri, Maayan Shapiro, Henrik Molina, Thomas Tuschl, Nahum Sonenberg
Published 2017-07-01

Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain

by Claudia Scheckel, Elodie Drapeau, Maria A Frias, Christopher Y Park, John Fak, Ilana Zucker-Scharff, Yan Kou, Vahram Haroutunian, Avi Ma'ayan, Joseph D Buxbaum, Robert B Darnell
Published 2016-02-01

Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells

by Charlotte Viant, Amelia Escolano, Spencer T. Chen, Michel C. Nussenzweig
Published 2021-06-01

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

by Lodoe Lama, Carolina Adura, Wei Xie, Daisuke Tomita, Taku Kamei, Vitaly Kuryavyi, Tasos Gogakos, Joshua I. Steinberg, Michael Miller, Lavoisier Ramos-Espiritu, Yasutomi Asano, Shogo Hashizume, Jumpei Aida, Toshihiro Imaeda, Rei Okamoto, Andy J. Jennings, Mayako Michino, Takanobu Kuroita, Andrew Stamford, Pu Gao, Peter Meinke, J. Fraser Glickman, Dinshaw J. Patel, Thomas Tuschl
Published 2019-05-01

Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses

by Ling Wang, Zachary Lee Johnson, Michael R Wasserman, Jesper Levring, Jue Chen, Shixin Liu
Published 2020-05-01

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure

by Taesun Eom, Chaolin Zhang, Huidong Wang, Kenneth Lay, John Fak, Jeffrey L Noebels, Robert B Darnell
Published 2013-01-01

Measurement of hindered diffusion in complex geometries for high-speed studies of single-molecule forces

by Tobias F. Bartsch, Camila M. Villasante, Felicitas E. Hengel, Ahmed Touré, Daniel M. Firester, Aaron Oswald, A. J. Hudspeth
Published 2021-01-01

Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons

by Yuan Yuan, Shirley Xie, Jennifer C. Darnell, Andrew J. Darnell, Yuhki Saito, Hemali Phatnani, Elisabeth A. Murphy, Chaolin Zhang, Tom Maniatis, Robert B. Darnell
Published 2018-08-01

In Vivo Production of Monoclonal Antibodies by Gene Transfer via Electroporation Protects against Lethal Influenza and Ebola Infections

by Chasity D. Andrews, Yang Luo, Ming Sun, Jian Yu, Arthur J. Goff, Pamela J. Glass, Neal N. Padte, Yaoxing Huang, David D. Ho
Published 2017-12-01

Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness

by Alexander Nguyen, Mitsukuni Yoshida, Hani Goodarzi, Sohail F. Tavazoie
Published 2016-05-01

PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage

by Hun-Way Hwang, Christopher Y. Park, Hani Goodarzi, John J. Fak, Aldo Mele, Michael J. Moore, Yuhki Saito, Robert B. Darnell
Published 2016-04-01

Localization of the PE methylation pathway and SR-BI to the canalicular membrane

by Ephraim Sehayek, Rong Wang, Jennie G. Ono, Vadim S. Zinchuk, Elizabeth M. Duncan, Sarah Shefer, Dennis E. Vance, Meenakshisundaram Ananthanarayanan, Brian T. Chait, Jan L. Breslow
Published 2003-09-01

CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex

by Brian Bae, James Chen, Elizabeth Davis, Katherine Leon, Seth A Darst, Elizabeth A Campbell
Published 2015-09-01

A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch

by Zijun Wang, Christopher O Barnes, Rajeev Gautam, Julio C Cetrulo Lorenzi, Christian T Mayer, Thiago Y Oliveira, Victor Ramos, Melissa Cipolla, Kristie M Gordon, Harry B Gristick, Anthony P West, Yoshiaki Nishimura, Henna Raina, Michael S Seaman, Anna Gazumyan, Malcolm Martin, Pamela J Bjorkman, Michel C Nussenzweig, Amelia Escolano
Published 2020-10-01

Analysis of the mechanosensor channel functionality of TACAN

by Yiming Niu, Xiao Tao, George Vaisey, Paul Dominic B Olinares, Hanan Alwaseem, Brian T Chait, Roderick MacKinnon
Published 2021-08-01

Fruitless mutant male mosquitoes gain attraction to human odor

by Nipun S Basrur, Maria Elena De Obaldia, Takeshi Morita, Margaret Herre, Ricarda K von Heynitz, Yael N Tsitohay, Leslie B Vosshall
Published 2020-12-01

HSF-1 activates the ubiquitin proteasome system to promote non-apoptotic developmental cell death in C. elegans

by Maxime J Kinet, Jennifer A Malin, Mary C Abraham, Elyse S Blum, Melanie R Silverman, Yun Lu, Shai Shaham
Published 2016-03-01

ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity

by Michael J Moore, Nathalie E Blachere, John J Fak, Christopher Y Park, Kirsty Sawicka, Salina Parveen, Ilana Zucker-Scharff, Bruno Moltedo, Alexander Y Rudensky, Robert B Darnell
Published 2018-05-01