Generation of six induced pluripotent stem cell lines from patients with amyotrophic lateral sclerosis with associated genetic mutations in either FUS or ANXA11

by Erin C. Hedges, Simon Topp, Christopher E. Shaw, Agnes L. Nishimura
Published 2021-04-01

Spatial Gradient of Microstructural Changes in Normal-Appearing White Matter in Tracts Affected by White Matter Hyperintensities in Older Age

by Susana Muñoz Maniega, Susana Muñoz Maniega, Susana Muñoz Maniega, Rozanna Meijboom, Rozanna Meijboom, Rozanna Meijboom, Rozanna Meijboom, Francesca M. Chappell, Francesca M. Chappell, Maria del C. Valdés Hernández, Maria del C. Valdés Hernández, Maria del C. Valdés Hernández, John M. Starr, John M. Starr, Mark E. Bastin, Mark E. Bastin, Ian J. Deary, Ian J. Deary, Joanna M. Wardlaw, Joanna M. Wardlaw, Joanna M. Wardlaw
Published 2019-07-01

Intracellular Sources of ROS/H₂O₂ in Health and Neurodegeneration: Spotlight on Endoplasmic Reticulum

by Tasuku Konno, Eduardo Pinho Melo, Joseph E. Chambers, Edward Avezov
Published 2021-01-01

Author Correction: Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing

by Farah H. Siddiqi, Fiona M. Menzies, Ana Lopez, Eleanna Stamatakou, Cansu Karabiyik, Rodrigo Ureshino, Thomas Ricketts, Maria Jimenez-Sanchez, Miguel Angel Esteban, Liangxue Lai, Micky D. Tortorella, Zhiwei Luo, Hao Liu, Emmanouil Metzakopian, Hugo J. R. Fernandes, Andrew Bassett, Eric Karran, Bruce L. Miller, Angeleen Fleming, David C. Rubinsztein
Published 2019-06-01

Soluble and insoluble dipeptide repeat protein measurements in C9orf72-frontotemporal dementia brains show regional differential solubility and correlation of poly-GR with clinical...

by Annelies Quaegebeur, Idoia Glaria, Tammaryn Lashley, Adrian M. Isaacs
Published 2020-11-01

HspB5 Activates a Neuroprotective Glial Cell Response in Experimental Tauopathy

by David W. Hampton, Sandra Amor, David Story, Megan Torvell, Malika Bsibsi, Johannes M. van Noort, Siddarthan Chandran, Siddarthan Chandran
Published 2020-06-01

The Temperature Dependence of Sleep

by Edward C. Harding, Nicholas P. Franks, Nicholas P. Franks, Nicholas P. Franks, William Wisden, William Wisden, William Wisden
Published 2019-04-01

Synaptopathy Mechanisms in ALS Caused by C9orf72 Repeat Expansion

by Agnes L. Nishimura, Natalia Arias, Natalia Arias
Published 2021-06-01

Corrigendum: Effects of Anthocyanin Supplementation on Serum Lipids, Glucose, Markers of Inflammation and Cognition in Adults With Increased Risk of Dementia – A Pilot Study

by Anne Katrine Bergland, Anne Katrine Bergland, Hogne Soennesyn, Ingvild Dalen, Ana Rodriguez-Mateos, Rolf Kristian Berge, Lasse Melvaer Giil, Lawrence Rajendran, Richard Siow, Michele Tassotti, Michele Tassotti, Alf Inge Larsen, Alf Inge Larsen, Dag Aarsland, Dag Aarsland
Published 2021-05-01

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations

by Rocío Rojo, Anna Raper, Derya D. Ozdemir, Lucas Lefevre, Kathleen Grabert, Evi Wollscheid-Lengeling, Barry Bradford, Melanie Caruso, Iveta Gazova, Alejandra Sánchez, Zofia M. Lisowski, Joana Alves, Irene Molina-Gonzalez, Hayk Davtyan, Rebecca J. Lodge, James D. Glover, Robert Wallace, David A. D. Munro, Eyal David, Ido Amit, Véronique E. Miron, Josef Priller, Stephen J. Jenkins, Giles E. Hardingham, Mathew Blurton-Jones, Neil A. Mabbott, Kim M. Summers, Peter Hohenstein, David A. Hume, Clare Pridans
Published 2019-07-01

FMRP Interacts with C/D Box snoRNA in the Nucleus and Regulates Ribosomal RNA Methylation

by Michelle Ninochka D'Souza, Naveen Kumar Chandappa Gowda, Vishal Tiwari, Rosana Ottakandathil Babu, Praveen Anand, Sudhriti Ghosh Dastidar, Randhir Singh, Owen G. James, Bhuvaneish Selvaraj, Rakhi Pal, Arati Ramesh, Sumantra Chattarji, Siddharthan Chandran, Akash Gulyani, Dasaradhi Palakodeti, Ravi S. Muddashetty
Published 2018-11-01

Therapeutic Targeting of Proteostasis in Amyotrophic Lateral Sclerosis—a Systematic Review and Meta-Analysis of Preclinical Research

by Elizabeth Elliott, Elizabeth Elliott, Elizabeth Elliott, Elizabeth Elliott, Elizabeth Elliott, Elizabeth Elliott, Olivia Bailey, Olivia Bailey, Olivia Bailey, Fergal M. Waldron, Giles E. Hardingham, Giles E. Hardingham, Giles E. Hardingham, Siddharthan Chandran, Siddharthan Chandran, Siddharthan Chandran, Siddharthan Chandran, Siddharthan Chandran, Siddharthan Chandran, Siddharthan Chandran, Siddharthan Chandran, Jenna M. Gregory, Jenna M. Gregory, Jenna M. Gregory, Jenna M. Gregory, Jenna M. Gregory, Jenna M. Gregory, Jenna M. Gregory
Published 2020-05-01

Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936

by Jamie Toombs, Lindsay Panther, Loren Ornelas, Chunyan Liu, Emilda Gomez, Raquel Martín-Ibáñez, Simon R. Cox, Stuart J. Ritchie, Sarah E. Harris, Adele Taylor, Paul Redmond, Tom C. Russ, Lee Murphy, James D. Cooper, Karen Burr, Bhuvaneish T. Selvaraj, Cathy Browne, Clive N. Svendsen, Sally A. Cowley, Ian J. Deary, Siddharthan Chandran, Tara L. Spires-Jones, Dhruv Sareen
Published 2020-07-01

Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies

by Tatiana Orme, Dena Hernandez, Owen A. Ross, Celia Kun-Rodrigues, Lee Darwent, Claire E. Shepherd, Laura Parkkinen, Olaf Ansorge, Lorraine Clark, Lawrence S. Honig, Karen Marder, Afina Lemstra, Ekaterina Rogaeva, Peter St. George-Hyslop, Elisabet Londos, Henrik Zetterberg, Kevin Morgan, Claire Troakes, Safa Al-Sarraj, Tammaryn Lashley, Janice Holton, Yaroslau Compta, Vivianna Van Deerlin, John Q. Trojanowski, Geidy E. Serrano, Thomas G. Beach, Suzanne Lesage, Douglas Galasko, Eliezer Masliah, Isabel Santana, Pau Pastor, Pentti J. Tienari, Liisa Myllykangas, Minna Oinas, Tamas Revesz, Andrew Lees, Brad F. Boeve, Ronald C. Petersen, Tanis J. Ferman, Valentina Escott-Price, Neill Graff-Radford, Nigel J. Cairns, John C. Morris, Stuart Pickering-Brown, David Mann, Glenda Halliday, David J. Stone, Dennis W. Dickson, John Hardy, Andrew Singleton, Rita Guerreiro, Jose Bras
Published 2020-01-01

Heritability and genetic variance of dementia with Lewy bodies

by Rita Guerreiro, Valentina Escott-Price, Dena G. Hernandez, Celia Kun-Rodrigues, Owen A. Ross, Tatiana Orme, Joao Luis Neto, Susana Carmona, Nadia Dehghani, John D. Eicher, Claire Shepherd, Laura Parkkinen, Lee Darwent, Michael G. Heckman, Sonja W. Scholz, Juan C. Troncoso, Olga Pletnikova, Ted Dawson, Liana Rosenthal, Olaf Ansorge, Jordi Clarimon, Alberto Lleo, Estrella Morenas-Rodriguez, Lorraine Clark, Lawrence S. Honig, Karen Marder, Afina Lemstra, Ekaterina Rogaeva, Peter St. George-Hyslop, Elisabet Londos, Henrik Zetterberg, Imelda Barber, Anne Braae, Kristelle Brown, Kevin Morgan, Claire Troakes, Safa Al-Sarraj, Tammaryn Lashley, Janice Holton, Yaroslau Compta, Vivianna Van Deerlin, Geidy E. Serrano, Thomas G. Beach, Suzanne Lesage, Douglas Galasko, Eliezer Masliah, Isabel Santana, Pau Pastor, Monica Diez-Fairen, Miquel Aguilar, Pentti J. Tienari, Liisa Myllykangas, Minna Oinas, Tamas Revesz, Andrew Lees, Brad F. Boeve, Ronald C. Petersen, Tanis J. Ferman, Neill Graff-Radford, Nigel J. Cairns, John C. Morris, Stuart Pickering-Brown, David Mann, Glenda M. Halliday, John Hardy, John Q. Trojanowski, Dennis W. Dickson, Andrew Singleton, David J. Stone, Jose Bras
Published 2019-07-01

Neurofilament light in blood – What more is needed for clinical implementation in multiple sclerosis?

by Henrik Zetterberg
Published 2020-07-01

Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing

by Farah H. Siddiqi, Fiona M. Menzies, Ana Lopez, Eleanna Stamatakou, Cansu Karabiyik, Rodrigo Ureshino, Thomas Ricketts, Maria Jimenez-Sanchez, Miguel Angel Esteban, Liangxue Lai, Micky D. Tortorella, Zhiwei Luo, Hao Liu, Emmanouil Metzakopian, Hugo J. R. Fernandes, Andrew Bassett, Eric Karran, Bruce L. Miller, Angeleen Fleming, David C. Rubinsztein
Published 2019-04-01

Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models

by Justin L. Tosh, Elena R. Rhymes, Paige Mumford, Heather T. Whittaker, Laura J. Pulford, Sue J. Noy, Karen Cleverley, LonDownS Consortium, Matthew C. Walker, Victor L. J. Tybulewicz, Rob C. Wykes, Elizabeth M. C. Fisher, Frances K. Wiseman
Published 2021-03-01

Polygenic Risk Scores in Alzheimer's Disease: Current Applications and Future Directions

by Emily Baker, Valentina Escott-Price, Valentina Escott-Price
Published 2020-08-01

Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer’s disease

by Ryan J. Bevan, Tim R. Hughes, Pete A. Williams, Mark A. Good, B. Paul Morgan, James E. Morgan
Published 2020-12-01