Stereological Investigation of Regional Brain Volumes after Acute and Chronic Cuprizone-Induced Demyelination

by Tanja Hochstrasser, Sebastian Rühling, Kerstin Hecher, Kai H. Fabisch, Uta Chrzanowski, Matthias Brendel, Florian Eckenweber, Christian Sacher, Christoph Schmitz, Markus Kipp
Published 2019-09-01

Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice

by Gloria Biechele, Karin Wind, Tanja Blume, Christian Sacher, Leonie Beyer, Florian Eckenweber, Nicolai Franzmeier, Michael Ewers, Benedikt Zott, Simon Lindner, Franz-Josef Gildehaus, Barbara von Ungern-Sternberg, Sabina Tahirovic, Michael Willem, Peter Bartenstein, Paul Cumming, Axel Rominger, Jochen Herms, Matthias Brendel
Published 2021-04-01

Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation

by Michael Ewers, Gloria Biechele, Marc Suárez‐Calvet, Christian Sacher, Tanja Blume, Estrella Morenas‐Rodriguez, Yuetiva Deming, Laura Piccio, Carlos Cruchaga, Gernot Kleinberger, Leslie Shaw, John Q Trojanowski, Jochen Herms, Martin Dichgans, the Alzheimer's Disease Neuroimaging Initiative (ADNI), Matthias Brendel, Christian Haass, Nicolai Franzmeier
Published 2020-09-01

Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases

by Gloria Biechele, Nicolai Franzmeier, Tanja Blume, Michael Ewers, Jose Medina Luque, Florian Eckenweber, Christian Sacher, Leonie Beyer, Francois Ruch-Rubinstein, Simon Lindner, Franz-Josef Gildehaus, Barbara von Ungern-Sternberg, Paul Cumming, Peter Bartenstein, Axel Rominger, Günter U. Höglinger, Jochen Herms, Matthias Brendel
Published 2020-12-01

Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning

by Florian Eckenweber, Jose Medina-Luque, Tanja Blume, Christian Sacher, Gloria Biechele, Karin Wind, Maximilian Deussing, Nils Briel, Simon Lindner, Guido Boening, Barbara von Ungern-Sternberg, Marcus Unterrainer, Nathalie L. Albert, Andreas Zwergal, Johannes Levin, Peter Bartenstein, Paul Cumming, Axel Rominger, Günter U. Höglinger, Jochen Herms, Matthias Brendel
Published 2020-07-01