Integration and relative value of biomarkers for prediction of MCI to AD progression: Spatial patterns of brain atrophy, cognitive scores, APOE genotype and CSF biomarkers

by Xiao Da, Jon B. Toledo, Jarcy Zee, David A. Wolk, Sharon X. Xie, Yangming Ou, Amanda Shacklett, Paraskevi Parmpi, Leslie Shaw, John Q. Trojanowski, Christos Davatzikos
Published 2014-01-01

ApoE4 effects on automated diagnostic classifiers for mild cognitive impairment and Alzheimer's disease

by Liana G. Apostolova, Kristy S. Hwang, Omid Kohannim, David Avila, David Elashoff, Clifford R. Jack, Jr., Leslie Shaw, John Q. Trojanowski, Michael W. Weiner, Paul M. Thompson
Published 2014-01-01

Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration

by Nicolai Franzmeier, M. Suárez-Calvet, Lukas Frontzkowski, Annah Moore, Timothy J. Hohman, Estrella Morenas-Rodriguez, Brigitte Nuscher, Leslie Shaw, John Q. Trojanowski, Martin Dichgans, Gernot Kleinberger, Christian Haass, Michael Ewers, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Published 2020-10-01

Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation

by Michael Ewers, Gloria Biechele, Marc Suárez‐Calvet, Christian Sacher, Tanja Blume, Estrella Morenas‐Rodriguez, Yuetiva Deming, Laura Piccio, Carlos Cruchaga, Gernot Kleinberger, Leslie Shaw, John Q Trojanowski, Jochen Herms, Martin Dichgans, the Alzheimer's Disease Neuroimaging Initiative (ADNI), Matthias Brendel, Christian Haass, Nicolai Franzmeier
Published 2020-09-01

Resting-State Functional Connectivity Is Associated With Cerebrospinal Fluid Levels of the Synaptic Protein NPTX2 in Non-demented Older Adults

by Anja Soldan, Abhay Moghekar, Keenan A. Walker, Corinne Pettigrew, Xirui Hou, Xirui Hou, Hanzhang Lu, Hanzhang Lu, Michael I. Miller, Alfonso Alfini, Marilyn Albert, Desheng Xu, Mei-Fang Xiao, Paul Worley, Paul Worley, The BIOCARD Research Team, John Csernansky, David Holtzman, David Knopman, Walter Kukull, Kevin Grimm, John Hsiao, Laurie Ryan, Constantine Lyketsos, Carlos Pardo, Gerard Schellenberg, Leslie Shaw, Madhav Thambisetty, John Trojanowski
Published 2019-06-01