Advances in Genomics for Drug Development

by Roberto Spreafico, Leah B. Soriaga, Johannes Grosse, Herbert W. Virgin, Amalio Telenti
Published 2020-08-01

Antibody-independent control of gamma-herpesvirus latency via B cell induction of anti-viral T cell responses.

by Kelly B McClellan, Shivaprakash Gangappa, Samuel H Speck, Herbert W Virgin
Published 2006-06-01

Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infection.

by Karen A Chachu, Anna D LoBue, David W Strong, Ralph S Baric, Herbert W Virgin
Published 2008-12-01

Correction: MDA-5 Recognition of a Murine Norovirus.

by Stephen A. McCartney, Larissa B. Thackray, Leonid Gitlin, Susan Gilfillan, Herbert W. Virgin, Marco Colonna
Published 2008-10-01

Correction: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.

by Timothy J Nice, Lisa C Osborne, Vesselin T Tomov, David Artis, E John Wherry, Herbert W Virgin
Published 2017-02-01

Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.

by Timothy J Nice, Lisa C Osborne, Vesselin T Tomov, David Artis, E John Wherry, Herbert W Virgin
Published 2016-06-01

MDA-5 recognition of a murine norovirus.

by Stephen A McCartney, Larissa B Thackray, Leonid Gitlin, Susan Gilfillan, Herbert W Virgin, Marco Colonna
Published 2008-07-01

Listeriolysin O is necessary and sufficient to induce autophagy during Listeria monocytogenes infection.

by Nicole Meyer-Morse, Jennifer R Robbins, Chris S Rae, Sofia N Mochegova, Michele S Swanson, Zijiang Zhao, Herbert W Virgin, Daniel Portnoy
Published 2010-01-01

Effective control of chronic gamma-herpesvirus infection by unconventional MHC Class Ia-independent CD8 T cells.

by Douglas C Braaten, James Scott McClellan, Ilhem Messaoudi, Scott A Tibbetts, Kelly B McClellan, Janko Nikolich-Zugich, Herbert W Virgin
Published 2006-05-01

Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.

by Elizabeth M Selleck, Sarah J Fentress, Wandy L Beatty, Daniel Degrandi, Klaus Pfeffer, Herbert W Virgin, John D Macmicking, L David Sibley
Published 2013-01-01

Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis.

by Volker Fensterl, Jaime L Wetzel, Srividya Ramachandran, Tomoaki Ogino, Stephen A Stohlman, Cornelia C Bergmann, Michael S Diamond, Herbert W Virgin, Ganes C Sen
Published 2012-01-01

A surface groove essential for viral Bcl-2 function during chronic infection in vivo.

by Joy Loh, Qiulong Huang, Andrew M Petros, David Nettesheim, Linda F van Dyk, Lucia Labrada, Samuel H Speck, Beth Levine, Edward T Olejniczak, Herbert W Virgin
Published 2005-09-01

Identification of novel viruses using VirusHunter--an automated data analysis pipeline.

by Guoyan Zhao, Siddharth Krishnamurthy, Zhengqiu Cai, Vsevolod L Popov, Amelia P Travassos da Rosa, Hilda Guzman, Song Cao, Herbert W Virgin, Robert B Tesh, David Wang
Published 2013-01-01

2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo.

by Kristy J Szretter, Brian P Daniels, Hyelim Cho, Maria D Gainey, Wayne M Yokoyama, Michael Gale, Herbert W Virgin, Robyn S Klein, Ganes C Sen, Michael S Diamond
Published 2012-01-01

Replication of Norovirus in cell culture reveals a tropism for dendritic cells and macrophages.

by Christiane E Wobus, Stephanie M Karst, Larissa B Thackray, Kyeong-Ok Chang, Stanislav V Sosnovtsev, Gaël Belliot, Anne Krug, Jason M Mackenzie, Kim Y Green, Herbert W Virgin
Published 2004-12-01

Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine–Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2

by Broc T. McCune, Wei Tang, Jia Lu, James B. Eaglesham, Lucy Thorne, Anne E. Mayer, Emily Condiff, Timothy J. Nice, Ian Goodfellow, Andrzej M. Krezel, Herbert W. Virgin, Terence S. Dermody
Published 2017-07-01

Correction: IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling.

by Helen M. Lazear, Alissa Lancaster, Courtney Wilkins, Mehul S. Suthar, Albert Huang, Sarah C. Vick, Lisa Clepper, Larissa Thackray, Margaret M. Brassil, Herbert W. Virgin, Janko Nikolich-Zugich, Ashlee V. Moses, Michael Gale, Klaus Früh, Michael S. Diamond
Published 2013-05-01

IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling.

by Helen M Lazear, Alissa Lancaster, Courtney Wilkins, Mehul S Suthar, Albert Huang, Sarah C Vick, Lisa Clepper, Larissa Thackray, Margaret M Brassil, Herbert W Virgin, Janko Nikolich-Zugich, Ashlee V Moses, Michael Gale, Klaus Früh, Michael S Diamond
Published 2013-01-01

A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis.

by Lisa K McLellan, Michael R McAllaster, Arthur S Kim, Ľubomíra Tóthová, Patrick D Olson, Jerome S Pinkner, Allyssa L Daugherty, Teri N Hreha, James W Janetka, Daved H Fremont, Scott J Hultgren, Herbert W Virgin, David A Hunstad
Published 2021-01-01

Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections

by Larissa B. Thackray, Scott A. Handley, Matthew J. Gorman, Subhajit Poddar, Prachi Bagadia, Carlos G. Briseño, Derek J. Theisen, Qing Tan, Barry L. Hykes, Jr., Hueylie Lin, Tiffany M. Lucas, Chandni Desai, Jeffrey I. Gordon, Kenneth M. Murphy, Herbert W. Virgin, Michael S. Diamond
Published 2018-03-01