Assessing the consequences of decentralizing biomedical research

by Brian M Bot, John T Wilbanks, Lara M Mangravite
Published 2019-06-01

Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs.

by Christopher D Brown, Lara M Mangravite, Barbara E Engelhardt
Published 2013-01-01

Correction: RHOA Is a Modulator of the Cholesterol-Lowering Effects of Statin

by Marisa W. Medina, Elizabeth Theusch, Devesh Naidoo, Frederick Bauzon, Kristen Stevens, Lara M. Mangravite, Yu-Lin Kuang, Ronald M. Krauss
Published 2013-02-01

RHOA is a modulator of the cholesterol-lowering effects of statin.

by Marisa W Medina, Elizabeth Theusch, Devesh Naidoo, Frederick Bauzon, Kristen Stevens, Lara M Mangravite, Yu-Lin Kuang, Ronald M Krauss
Published 2012-01-01

Correction: RHOA Is a Modulator of the Cholesterol-Lowering Effects of Statin.

by Marisa W. Medina, Elizabeth Theusch, Devesh Naidoo, Frederick Bauzon, Kristen Stevens, Lara M. Mangravite, Yu-Lin Kuang, Ronald M. Krauss
Published 2013-02-01

Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer’s disease

by Jake Gockley, Kelsey S. Montgomery, William L. Poehlman, Jesse C. Wiley, Yue Liu, Ekaterina Gerasimov, Anna K. Greenwood, Solveig K. Sieberts, Aliza P. Wingo, Thomas S. Wingo, Lara M. Mangravite, Benjamin A. Logsdon
Published 2021-05-01

Author Correction: Molecular estimation of neurodegeneration pseudotime in older brains

by Sumit Mukherjee, Laura Heath, Christoph Preuss, Suman Jayadev, Gwenn A. Garden, Anna K. Greenwood, Solveig K. Sieberts, Philip L. De Jager, Nilüfer Ertekin-Taner, Gregory W. Carter, Lara M. Mangravite, Benjamin A. Logsdon
Published 2020-12-01

Molecular estimation of neurodegeneration pseudotime in older brains

by Sumit Mukherjee, Laura Heath, Christoph Preuss, Suman Jayadev, Gwenn A. Garden, Anna K. Greenwood, Solveig K. Sieberts, Philip L. De Jager, Nilüfer Ertekin-Taner, Gregory W. Carter, Lara M. Mangravite, Benjamin A. Logsdon
Published 2020-11-01

A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease

by Christoph Preuss, Ravi Pandey, Erin Piazza, Alexander Fine, Asli Uyar, Thanneer Perumal, Dylan Garceau, Kevin P. Kotredes, Harriet Williams, Lara M. Mangravite, Bruce T. Lamb, Adrian L. Oblak, Gareth R. Howell, Michael Sasner, Benjamin A. Logsdon, the MODEL-AD Consortium, Gregory W. Carter
Published 2020-11-01

Genome-wide association of lipid-lowering response to statins in combined study populations.

by Mathew J Barber, Lara M Mangravite, Craig L Hyde, Daniel I Chasman, Joshua D Smith, Catherine A McCarty, Xiaohui Li, Russell A Wilke, Mark J Rieder, Paul T Williams, Paul M Ridker, Aurobindo Chatterjee, Jerome I Rotter, Deborah A Nickerson, Matthew Stephens, Ronald M Krauss
Published 2010-03-01

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.

by Denis A Baird, Jimmy Z Liu, Jie Zheng, Solveig K Sieberts, Thanneer Perumal, Benjamin Elsworth, Tom G Richardson, Chia-Yen Chen, Minerva M Carrasquillo, Mariet Allen, Joseph S Reddy, Philip L De Jager, Nilufer Ertekin-Taner, Lara M Mangravite, Ben Logsdon, Karol Estrada, Philip C Haycock, Gibran Hemani, Heiko Runz, George Davey Smith, Tom R Gaunt, AMP-AD eQTL working group
Published 2021-01-01

A community approach to mortality prediction in sepsis via gene expression analysis

by Timothy E. Sweeney, Thanneer M. Perumal, Ricardo Henao, Marshall Nichols, Judith A. Howrylak, Augustine M. Choi, Jesús F. Bermejo-Martin, Raquel Almansa, Eduardo Tamayo, Emma E. Davenport, Katie L. Burnham, Charles J. Hinds, Julian C. Knight, Christopher W. Woods, Stephen F. Kingsmore, Geoffrey S. Ginsburg, Hector R. Wong, Grant P. Parnell, Benjamin Tang, Lyle L. Moldawer, Frederick E. Moore, Larsson Omberg, Purvesh Khatri, Ephraim L. Tsalik, Lara M. Mangravite, Raymond J. Langley
Published 2018-02-01

A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection

by Slim Fourati, Aarthi Talla, Mehrad Mahmoudian, Joshua G. Burkhart, Riku Klén, Ricardo Henao, Thomas Yu, Zafer Aydın, Ka Yee Yeung, Mehmet Eren Ahsen, Reem Almugbel, Samad Jahandideh, Xiao Liang, Torbjörn E. M. Nordling, Motoki Shiga, Ana Stanescu, Robert Vogel, The Respiratory Viral DREAM Challenge Consortium, Gaurav Pandey, Christopher Chiu, Micah T. McClain, Christopher W. Woods, Geoffrey S. Ginsburg, Laura L. Elo, Ephraim L. Tsalik, Lara M. Mangravite, Solveig K. Sieberts
Published 2018-10-01

Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study

by Adrian L. Oblak, Adrian L. Oblak, Peter B. Lin, Kevin P. Kotredes, Ravi S. Pandey, Dylan Garceau, Harriet M. Williams, Asli Uyar, Rita O’Rourke, Sarah O’Rourke, Cynthia Ingraham, Daria Bednarczyk, Melisa Belanger, Zackary A. Cope, Gabriela J. Little, Sean-Paul G. Williams, Carl Ash, Adam Bleckert, Tim Ragan, Benjamin A. Logsdon, Lara M. Mangravite, Stacey J. Sukoff Rizzo, Paul R. Territo, Paul R. Territo, Gregory W. Carter, Gareth R. Howell, Michael Sasner, Bruce T. Lamb, Bruce T. Lamb
Published 2021-07-01

An open toolkit for tracking open science partnership implementation and impact [version 2; peer review: 2 approved]

by E. Richard Gold, Sarah E. Ali-Khan, Liz Allen, Lluis Ballell, Manoel Barral-Netto, David Carr, Damien Chalaud, Simon Chaplin, Matthew S. Clancy, Patricia Clarke, Robert Cook-Deegan, A. P. Dinsmore, Megan Doerr, Lisa Federer, Steven A. Hill, Neil Jacobs, Antoine Jean, Osmat Azzam Jefferson, Chonnettia Jones, Linda J. Kahl, Thomas M. Kariuki, Sophie N. Kassel, Robert Kiley, Elizabeth Robboy Kittrie, Bianca Kramer, Wen Hwa Lee, Emily MacDonald, Lara M. Mangravite, Elizabeth Marincola, Daniel Mietchen, Jennifer C. Molloy, Mark Namchuk, Brian A. Nosek, Sébastien Paquet, Claude Pirmez, Annabel Seyller, Malcolm Skingle, S. Nicole Spadotto, Sophie Staniszewska, Mike Thelwall
Published 2019-12-01

Crowdsourcing digital health measures to predict Parkinson’s disease severity: the Parkinson’s Disease Digital Biomarker DREAM Challenge

by Solveig K. Sieberts, Jennifer Schaff, Marlena Duda, Bálint Ármin Pataki, Ming Sun, Phil Snyder, Jean-Francois Daneault, Federico Parisi, Gianluca Costante, Udi Rubin, Peter Banda, Yooree Chae, Elias Chaibub Neto, E. Ray Dorsey, Zafer Aydın, Aipeng Chen, Laura L. Elo, Carlos Espino, Enrico Glaab, Ethan Goan, Fatemeh Noushin Golabchi, Yasin Görmez, Maria K. Jaakkola, Jitendra Jonnagaddala, Riku Klén, Dongmei Li, Christian McDaniel, Dimitri Perrin, Thanneer M. Perumal, Nastaran Mohammadian Rad, Erin Rainaldi, Stefano Sapienza, Patrick Schwab, Nikolai Shokhirev, Mikko S. Venäläinen, Gloria Vergara-Diaz, Yuqian Zhang, the Parkinson’s Disease Digital Biomarker Challenge Consortium, Yuanjia Wang, Yuanfang Guan, Daniela Brunner, Paolo Bonato, Lara M. Mangravite, Larsson Omberg
Published 2021-03-01

Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models

by Ying-Wooi Wan, Rami Al-Ouran, Carl G. Mangleburg, Thanneer M. Perumal, Tom V. Lee, Katherine Allison, Vivek Swarup, Cory C. Funk, Chris Gaiteri, Mariet Allen, Minghui Wang, Sarah M. Neuner, Catherine C. Kaczorowski, Vivek M. Philip, Gareth R. Howell, Heidi Martini-Stoica, Hui Zheng, Hongkang Mei, Xiaoyan Zhong, Jungwoo Wren Kim, Valina L. Dawson, Ted M. Dawson, Ping-Chieh Pao, Li-Huei Tsai, Jean-Vianney Haure-Mirande, Michelle E. Ehrlich, Paramita Chakrabarty, Yona Levites, Xue Wang, Eric B. Dammer, Gyan Srivastava, Sumit Mukherjee, Solveig K. Sieberts, Larsson Omberg, Kristen D. Dang, James A. Eddy, Phil Snyder, Yooree Chae, Sandeep Amberkar, Wenbin Wei, Winston Hide, Christoph Preuss, Ayla Ergun, Phillip J. Ebert, David C. Airey, Sara Mostafavi, Lei Yu, Hans-Ulrich Klein, Gregory W. Carter, David A. Collier, Todd E. Golde, Allan I. Levey, David A. Bennett, Karol Estrada, T. Matthew Townsend, Bin Zhang, Eric Schadt, Philip L. De Jager, Nathan D. Price, Nilüfer Ertekin-Taner, Zhandong Liu, Joshua M. Shulman, Lara M. Mangravite, Benjamin A. Logsdon
Published 2020-07-01

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

by Solveig K. Sieberts, Fan Zhu, Javier García-García, Eli Stahl, Abhishek Pratap, Gaurav Pandey, Dimitrios Pappas, Daniel Aguilar, Bernat Anton, Jaume Bonet, Ridvan Eksi, Oriol Fornés, Emre Guney, Hongdong Li, Manuel Alejandro Marín, Bharat Panwar, Joan Planas-Iglesias, Daniel Poglayen, Jing Cui, Andre O. Falcao, Christine Suver, Bruce Hoff, Venkat S. K. Balagurusamy, Donna Dillenberger, Elias Chaibub Neto, Thea Norman, Tero Aittokallio, Muhammad Ammad-ud-din, Chloe-Agathe Azencott, Víctor Bellón, Valentina Boeva, Kerstin Bunte, Himanshu Chheda, Lu Cheng, Jukka Corander, Michel Dumontier, Anna Goldenberg, Peddinti Gopalacharyulu, Mohsen Hajiloo, Daniel Hidru, Alok Jaiswal, Samuel Kaski, Beyrem Khalfaoui, Suleiman Ali Khan, Eric R. Kramer, Pekka Marttinen, Aziz M. Mezlini, Bhuvan Molparia, Matti Pirinen, Janna Saarela, Matthias Samwald, Véronique Stoven, Hao Tang, Jing Tang, Ali Torkamani, Jean-Phillipe Vert, Bo Wang, Tao Wang, Krister Wennerberg, Nathan E. Wineinger, Guanghua Xiao, Yang Xie, Rae Yeung, Xiaowei Zhan, Cheng Zhao, Members of the Rheumatoid Arthritis Challenge Consortium, Jeff Greenberg, Joel Kremer, Kaleb Michaud, Anne Barton, Marieke Coenen, Xavier Mariette, Corinne Miceli, Nancy Shadick, Michael Weinblatt, Niek de Vries, Paul P. Tak, Danielle Gerlag, Tom W. J. Huizinga, Fina Kurreeman, Cornelia F. Allaart, S. Louis Bridges Jr., Lindsey Criswell, Larry Moreland, Lars Klareskog, Saedis Saevarsdottir, Leonid Padyukov, Peter K. Gregersen, Stephen Friend, Robert Plenge, Gustavo Stolovitzky, Baldo Oliva, Yuanfang Guan, Lara M. Mangravite
Published 2016-08-01

Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

by Solveig K. Sieberts, Fan Zhu, Javier García-García, Eli Stahl, Abhishek Pratap, Gaurav Pandey, Dimitrios Pappas, Daniel Aguilar, Bernat Anton, Jaume Bonet, Ridvan Eksi, Oriol Fornés, Emre Guney, Hongdong Li, Manuel Alejandro Marín, Bharat Panwar, Joan Planas-Iglesias, Daniel Poglayen, Jing Cui, Andre O. Falcao, Christine Suver, Bruce Hoff, Venkat S. K. Balagurusamy, Donna Dillenberger, Elias Chaibub Neto, Thea Norman, Tero Aittokallio, Muhammad Ammad-ud-din, Chloe-Agathe Azencott, Víctor Bellón, Valentina Boeva, Kerstin Bunte, Himanshu Chheda, Lu Cheng, Jukka Corander, Michel Dumontier, Anna Goldenberg, Peddinti Gopalacharyulu, Mohsen Hajiloo, Daniel Hidru, Alok Jaiswal, Samuel Kaski, Beyrem Khalfaoui, Suleiman Ali Khan, Eric R. Kramer, Pekka Marttinen, Aziz M. Mezlini, Bhuvan Molparia, Matti Pirinen, Janna Saarela, Matthias Samwald, Véronique Stoven, Hao Tang, Jing Tang, Ali Torkamani, Jean-Phillipe Vert, Bo Wang, Tao Wang, Krister Wennerberg, Nathan E. Wineinger, Guanghua Xiao, Yang Xie, Rae Yeung, Xiaowei Zhan, Cheng Zhao, Members of the Rheumatoid Arthritis Challenge Consortium, Jeff Greenberg, Joel Kremer, Kaleb Michaud, Anne Barton, Marieke Coenen, Xavier Mariette, Corinne Miceli, Nancy Shadick, Michael Weinblatt, Niek de Vries, Paul P. Tak, Danielle Gerlag, Tom W. J. Huizinga, Fina Kurreeman, Cornelia F. Allaart, S. Louis Bridges Jr., Lindsey Criswell, Larry Moreland, Lars Klareskog, Saedis Saevarsdottir, Leonid Padyukov, Peter K. Gregersen, Stephen Friend, Robert Plenge, Gustavo Stolovitzky, Baldo Oliva, Yuanfang Guan, Lara M. Mangravite
Published 2016-10-01