Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells

by Giraud, Matthieu, Yoshida, Hideyuki, Abramson, Jakub, Rahl, Peter B., Young, Richard A., Mathis, Diane, Benoist, Christophe
Published 2012

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

by Lin, Charles Y., Loven, Jakob, Rahl, Peter B, Paranal, Ronald M, Burge, Christopher B., Bradner, James E., Lee, Tong Ihn, Young, Richard A
Published 2014

c-Myc regulates transcriptional pause release

by Rahl, Peter B., Lin, Charles Y., Flynn, Ryan A., McCuine, Scott, Sharp, Phillip A., Young, Richard A., White, Amy C., Burge, Christopher B
Published 2012

Revisiting Global Gene Expression Analysis

by Loven, Jakob, Orlando, David A., Sigova, Alla A, Lin, Charles Y., Rahl, Peter B, Burge, Christopher B., Levens, David L, Lee, Tong Ihn, Young, Richard A
Published 2015

Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts

by Gurtan, Allan M., Ravi, Arvind, Bosson, Andrew David, JnBaptiste, Courtney Kenneil, Bhutkar, Arjun (AJ), Whittaker, Charles A., Young, Richard A., Sharp, Phillip A., Rahl, Peter B.
Published 2014

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

by Whyte, Warren A, Orlando, David A, Hnisz, Denes, Abraham, Brian J, Lin, Charles Y, Kagey, Michael H, Rahl, Peter B, Lee, Tong Ihn, Young, Richard A, Young, Richard A.
Published 2016

Functional Association of Gdown1 with RNA Polymerase II Poised on Human Genes

by Cheng, Bo, Li, Tiandao, Rahl, Peter B, Adamson, Todd E, Loudas, Nicholas B, Guo, Jiannan, Varzavand, Katayoun, Cooper, Jeffrey J, Hu, Xiaopeng, Gnatt, Averell, Price, David H, Young, Richard A.
Published 2018

Genome-wide localization of small molecules

by Anders, Lars, Guenther, Matthew G., Qi, Jun, Fan, Zi Peng, Marineau, Jason J, Rahl, Peter B, Sigova, Alla A, Smith, William B, Lee, Tong Ihn, Bradner, James E., Young, Richard A., Loven, Jakob
Published 2015

Mediator and cohesin connect gene expression and chromatin architecture

by Kagey, Michael H., Newman, Jamie Jennifer, Bilodeau, Steve, Zhan, Ye, Orlando, David A., van Berkum, Nynke L., Ebmeier, Christopher C., Goossens, Jesse, Rahl, Peter B., Levine, Stuart S., Taatjes, Dylan J., Dekker, Job, Young, Richard A.
Published 2012

BET bromodomain proteins regulate enhancer function during adipogenesis

by Brown, Jonathan D., Feldman, Zachary B., Doherty, Sean P., Reyes, Jaime M., Rahl, Peter B., Lin, Charles Y., Sheng, Quanhu, Duan, Qiong, Federation, Alexander J., Kung, Andrew L., Haldar, Saptarsi M., Plutzky, Jorge, Bradner, James E., Young, Richard A.
Published 2018

Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma

by Chapuy, Bjoern, McKeown, Michael R, Lin, Charles Y, Monti, Stefano, Roemer, Margaretha G.M, Qi, Jun, Rahl, Peter B, Sun, Heather H, Yeda, Kelly T, Doench, John G, Reichert, Elaine, Kung, Andrew L, Rodig, Scott J, Young, Richard A, Shipp, Margaret A, Bradner, James E, Young, Richard A.
Published 2016

DHODH modulates transcriptional elongation in the neural crest and melanoma

by White, Richard Mark, Cech, Jennifer N., Ratanasirintrawoot, Sutheera, Lin, Charles Y., Rahl, Peter B., Burke, Christopher J., Langdon, Erin, Tomlinson, Matthew L., Mosher, Jack, Kaufman, Charles, Chen, Frank, Long, Hannah K., Kramer, Martin, Datta, Sumon, Neuberg, Donna S., Granter, Scott, Young, Richard A., Morrison, Sean, Wheeler, Grant N., Zon, Leonard I.
Published 2014

Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms

by Xiao, Sheng, Yosef, Nir, Yang, Jianfei, Wang, Yonghui, Zhou, Ling, Zhu, Chen, Wu, Chuan, Baloglu, Erkan, Schmidt, Darby, Ramesh, Radha, Lobera, Mercedes, Sundrud, Mark S, Tsai, Pei-Yun, Xiang, Zhijun, Wang, Jinsong, Xu, Yan, Lin, Xichen, Kretschmer, Karsten, Rahl, Peter B, Zhong, Zhong, Hafler, David A, Ghosh, Shomir, Marson, Alexander, Kuchroo, Vijay K, Regev, Aviv, Young, Richard A.
Published 2017

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

by Kwiatkowski, Nicholas P., Zhang, Tinghu, Rahl, Peter B., Abraham, Brian J., Reddy, Jessica, Ficarro, Scott B., Dastur, Anahita, Amzallag, Arnaud, Ramaswamy, Sridhar, Tesar, Bethany, Jenkins, Catherine E., Hannett, Nancy M., McMillin, Douglas, Sanda, Takaomi, Sim, Taebo, Kim, Nam Doo, Look, A. Thomas, Mitsiades, Constantine S., Weng, Andrew P., Brown, Jennifer R., Benes, Cyril H., Marto, Jarrod A., Young, Richard A., Gray, Nathanael S.
Published 2015

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

by Delmore, Jake E, Issa, Ghayas C, Lemieux, Madeleine E., Rahl, Peter B, Shi, Junwei, Jacobs, Hannah M, Kastritis, Efstathios, Gilpatrick, Timothy, Paranal, Ronald M, Qi, Jun, Chesi, Marta, Schinzel, Anna C, McKeown, Michael R, Heffernan, Timothy P., Vakoc, Christopher R, Bergsagel, P. Leif, Ghobrial, Irene M., Richardson, Paul G, Young, Richard A, Hahn, William C., Anderson, Kenneth C., Kung, Andrew L, Bradner, James E., Mitsiades, Constantine S.
Published 2014