Lymph Node Cellular and Viral Dynamics in Natural Hosts and Impact for HIV Cure Strategies

by Nicolas Huot, Nicolas Huot, Steven E. Bosinger, Steven E. Bosinger, Mirko Paiardini, R. Keith Reeves, R. Keith Reeves, Michaela Müller-Trutwin, Michaela Müller-Trutwin
Published 2018-04-01

Delineation and Modulation of the Natural Killer Cell Transcriptome in Rhesus Macaques During ZIKV and SIV Infections

by Malika Aid, Daniel R. Ram, Steven E. Bosinger, Dan H. Barouch, Dan H. Barouch, R. Keith Reeves, R. Keith Reeves
Published 2020-04-01

Chromatin accessibility and transcription dynamics during in vitro astrocyte differentiation of Huntington’s Disease Monkey pluripotent stem cells

by Alexandra V. Goodnight, Isaac Kremsky, Sujittra Khampang, Yoon Hee Jung, James M. Billingsley, Steven E. Bosinger, Victor G. Corces, Anthony W. S. Chan
Published 2019-11-01

Coexpression Network Analysis of Benign and Malignant Phenotypes of SIV-Infected Sooty Mangabey and Rhesus Macaque.

by Zhao-Wan Yang, Yan-Hua Jiang, Chuang Ma, Guido Silvestri, Steven E Bosinger, Bai-Lian Li, Ambrose Jong, Yan-Hong Zhou, Sheng-He Huang
Published 2016-01-01

Innate, non-cytolytic CD8+ T cell-mediated suppression of HIV replication by MHC-independent inhibition of virus transcription.

by Michelle Zanoni, David Palesch, Claudia Pinacchio, Maura Statzu, Gregory K Tharp, Mirko Paiardini, Ann Chahroudi, Steven E Bosinger, Jack Yoon, Bryan Cox, Guido Silvestri, Deanna A Kulpa
Published 2020-09-01

Intact type I Interferon production and IRF7 function in sooty mangabeys.

by Steven E Bosinger, Zachary P Johnson, Kathryn A Folkner, Nirav Patel, Tayebeh Hashempour, Simon P Jochems, Perla M Del Rio Estrada, Mirko Paiardini, Rongtuan Lin, Thomas H Vanderford, John Hiscott, Guido Silvestri
Published 2013-01-01

CD8 depletion plus signaling of the non-canonical NF-kB pathway reverses latency in SIV-infected, ART-suppressed rhesus macaques

by M. Mavigner, A.D. Brooks, G.K. Tharp, C. Mattingly, N. Schoof, T.H. Vanderford, S.E. Bosinger, G.C. Sampey, C. Galardi, R.M. Dunham, D.M. Margolis, G. Silvestri, A. Chahroudi
Published 2019-07-01

Clinical and whole genome characterization of SARS-CoV-2 in India.

by Radhakrishna Muttineni, Nagamani Kammili, Thrilok Chander Bingi, Raja Rao M, Kalyani Putty, Pankaj Singh Dholaniya, Ravi Kumar Puli, Sunitha Pakalapati, Saritha S, Shekar K, Mallikarjuna Reddy Doodipala, Amit A Upadhyay, Steven E Bosinger, Rama R Amara, Anand K Kondapi
Published 2021-01-01

BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data

by Amit A. Upadhyay, Robert C. Kauffman, Amber N. Wolabaugh, Alice Cho, Nirav B. Patel, Samantha M. Reiss, Colin Havenar-Daughton, Reem A. Dawoud, Gregory K. Tharp, Iñaki Sanz, Bali Pulendran, Shane Crotty, F. Eun-Hyung Lee, Jens Wrammert, Steven E. Bosinger
Published 2018-03-01

Transcriptomic and Metabolic Responses to a Live-Attenuated <i>Francisella tularensis</i> Vaccine

by Johannes B. Goll, Shuzhao Li, James L. Edwards, Steven E. Bosinger, Travis L. Jensen, Yating Wang, William F. Hooper, Casey E. Gelber, Katherine L. Sanders, Evan J. Anderson, Nadine Rouphael, Muktha S. Natrajan, Robert A. Johnson, Patrick Sanz, Daniel Hoft, Mark J. Mulligan
Published 2020-07-01

Ex vivo Stimulatory Capacity of TLR3 and TLR4 is reduced in HIV-Infected Rapid Progressors and Enhanced Long-Term Non-Progressors

by Steven E. Bosinger,1,2 Prameet M. Sheth,3 Ali Danesh,2,4 Leonard Noay,5 Roberta Halpenny,5 Shari Gordon,6,7,8 Silvija Staprans,7,8 Guido Silvestri,6 Colin Kovacs,5 Rupert Kaul,3 and David J. Kelvin.2,4
Published 2007-08-01

Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial

by Christina Balle, Iyaloo N. Konstantinus, Shameem Z. Jaumdally, Enock Havyarimana, Katie Lennard, Rachel Esra, Shaun L. Barnabas, Anna-Ursula Happel, Zoe Moodie, Katherine Gill, Tanya Pidwell, Ulas Karaoz, Eoin Brodie, Venessa Maseko, Hoyam Gamieldien, Steven E. Bosinger, Landon Myer, Linda-Gail Bekker, Jo-Ann S. Passmore, Heather B. Jaspan
Published 2020-11-01

Alterations in the Human Plasma Lipidome in Response to Tularemia Vaccination

by Kristal M. Maner-Smith, Johannes B. Goll, Manoj Khadka, Travis L. Jensen, Jennifer K. Colucci, Casey E. Gelber, Carolyn J. Albert, Steven E. Bosinger, Jacob D. Franke, Muktha Natrajan, Nadine Rouphael, Robert A. Johnson, Patrick Sanz, Evan J. Anderson, Daniel F. Hoft, Mark J. Mulligan, David A. Ford, Eric A. Ortlund
Published 2020-07-01

Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replica...

by Krystelle Nganou-Makamdop, James M Billingsley, Zachary Yaffe, Gregory O'Connor, Gregory K Tharp, Amy Ransier, Farida Laboune, Rodrigo Matus-Nicodemos, Andrea Lerner, Lavina Gharu, Jennifer M Robertson, Mandy L Ford, Martin Schlapschy, Nadine Kuhn, Alexandra Lensch, Jeffrey Lifson, Martha Nason, Arne Skerra, Gideon Schreiber, Steven E Bosinger, Daniel C Douek
Published 2018-08-01

Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals.

by Nichole R Klatt, Steven E Bosinger, Melicent Peck, Laura E Richert-Spuhler, Anke Heigele, Jillian P Gile, Nirav Patel, Jessica Taaffe, Boris Julg, David Camerini, Carlo Torti, Jeffrey N Martin, Steven G Deeks, Elizabeth Sinclair, Frederick M Hecht, Michael M Lederman, Mirko Paiardini, Frank Kirchhoff, Jason M Brenchley, Peter W Hunt, Guido Silvestri
Published 2014-08-01

Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization

by Colin Havenar-Daughton, Diane G. Carnathan, Archana V. Boopathy, Amit A. Upadhyay, Ben Murrell, Samantha M. Reiss, Chiamaka A. Enemuo, Etse H. Gebru, Yury Choe, Pallavi Dhadvai, Federico Viviano, Kirti Kaushik, Jinal N. Bhiman, Bryan Briney, Dennis R. Burton, Steven E. Bosinger, William R. Schief, Darrell J. Irvine, Guido Silvestri, Shane Crotty
Published 2019-11-01

Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control

by Fredrik Barrenas, Kevin Raehtz, Cuiling Xu, Lynn Law, Richard R. Green, Guido Silvestri, Steven E. Bosinger, Andrew Nishida, Qingsheng Li, Wuxun Lu, Jianshui Zhang, Matthew J. Thomas, Jean Chang, Elise Smith, Jeffrey M. Weiss, Reem A. Dawoud, George H. Richter, Anita Trichel, Dongzhu Ma, Xinxia Peng, Jan Komorowski, Cristian Apetrei, Ivona Pandrea, Michael Gale
Published 2019-11-01

Author Correction: Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control

by Fredrik Barrenas, Kevin Raehtz, Cuiling Xu, Lynn Law, Richard R. Green, Guido Silvestri, Steven E. Bosinger, Andrew Nishida, Qingsheng Li, Wuxun Lu, Jianshui Zhang, Matthew J. Thomas, Jean Chang, Elise Smith, Jeffrey M. Weiss, Reem A. Dawoud, George H. Richter, Anita Trichel, Dongzhu Ma, Xinxia Peng, Jan Komorowski, Cristian Apetrei, Ivona Pandrea, Michael Gale
Published 2019-12-01

Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity

by Simone Joas, Erica H. Parrish, Clement W. Gnanadurai, Edina Lump, Christina M. Stürzel, Nicholas F. Parrish, Gerald H. Learn, Ulrike Sauermann, Berit Neumann, Kerstin Mätz Rensing, Dietmar Fuchs, James M. Billingsley, Steven E. Bosinger, Guido Silvestri, Cristian Apetrei, Nicolas Huot, Thalia Garcia-Tellez, Michaela Müller-Trutwin, Dominik Hotter, Daniel Sauter, Christiane Stahl-Hennig, Beatrice H. Hahn, Frank Kirchhoff
Published 2018-04-01

Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection.

by Michelle Y-H Lee, Amit A Upadhyay, Hasse Walum, Chi N Chan, Reem A Dawoud, Christine Grech, Justin L Harper, Kirti A Karunakaran, Sydney A Nelson, Ernestine A Mahar, Kyndal L Goss, Diane G Carnathan, Barbara Cervasi, Kiran Gill, Gregory K Tharp, Elizabeth R Wonderlich, Vijayakumar Velu, Simon M Barratt-Boyes, Mirko Paiardini, Guido Silvestri, Jacob D Estes, Steven E Bosinger
Published 2021-06-01