Pulmonary Arterial Hypertension: Iron Matters

by Latha Ramakrishnan, Sofia L. Pedersen, Quezia K. Toe, Gregory J. Quinlan, Stephen J. Wort
Published 2018-05-01

miR-1-5p targets TGF-βR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension.

by Martin Connolly, Benjamin E Garfield, Alexi Crosby, Nick W Morrell, Stephen J Wort, Paul R Kemp
Published 2020-01-01

The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension.

by Louise S Harrington, Laura Moreno, Anna Reed, Stephen J Wort, Béatrice Desvergne, Christopher Garland, Lan Zhao, Jane A Mitchell
Published 2010-03-01

Outcome of cardiac surgery in patients with congenital heart disease in England between 1997 and 2015.

by Aleksander Kempny, Konstantinos Dimopoulos, Anselm Uebing, Gerhard-Paul Diller, Ulrich Rosendahl, George Belitsis, Michael A Gatzoulis, Stephen J Wort
Published 2017-01-01

BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production.

by John E S Park, Dongmin Shao, Paul D Upton, Patricia Desouza, Ian M Adcock, Rachel J Davies, Nicholas W Morrell, Mark J D Griffiths, Stephen J Wort
Published 2012-01-01

Correction: BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production

by John E. S. Park, Dongmin Shao, Paul D. Upton, Patricia deSouza, Ian M. Adcock, Rachel J. Davies, Nicholas W. Morrell, Mark J. D. Griffiths, Stephen J. Wort
Published 2013-01-01

Rescue therapy with thrombolysis in patients with severe COVID-19-associated acute respiratory distress syndrome

by Laura C. Price, Benjamin Garfield, Caroline Bleakley, Archie G.M. Keeling, Charles Mcfadyen, Colm McCabe, Carole A. Ridge, Stephen J. Wort, Susanna Price, Deepa J. Arachchillage
Published 2020-12-01

Correction: BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production.

by John E. S. Park, Dongmin Shao, Paul D. Upton, Patricia deSouza, Ian M. Adcock, Rachel J. Davies, Nicholas W. Morrell, Mark J. D. Griffiths, Stephen J. Wort
Published 2013-01-01

Extracellular matrix degradation pathways and fatty acid metabolism regulate distinct pulmonary vascular cell types in pulmonary arterial hypertension

by Sharon Mumby, F. Perros, C. Hui, B.L. Xu, W. Xu, V Elyasigomari, A. Hautefort, G. Manaud, M. Humbert, K.F. Chung, S.J. Wort, I.M. Adcock
Published 2021-03-01

Prognostic implications of pulmonary wave reflection and reservoir pressure in patients with pulmonary hypertension

by K. Wustmann, A. Constantine, J.E. Davies, W. Li, D. Pennell, S.J. Wort, A. Kempny, L.C. Price, C. McCabe, R. Mohiaddin, D.P. Francis, M.A. Gatzoulis, K. Dimopoulos
Published 2021-10-01

miR‐424‐5p reduces ribosomal RNA and protein synthesis in muscle wasting

by Martin Connolly, Richard Paul, Roser Farre‐Garros, Samantha A. Natanek, Susannah Bloch, Jen Lee, Jose P. Lorenzo, Harnish Patel, Cyrus Cooper, Avan A. Sayer, Stephen J. Wort, Mark Griffiths, Michael I. Polkey, Paul R. Kemp
Published 2018-04-01

Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI)

by David G. Kiely, David L. Levin, Paul M. Hassoun, Dunbar Ivy, Pei-Ni Jone, Jumaa Bwika, Steven M. Kawut, Jim Lordan, Angela Lungu, Jeremy A. Mazurek, Shahin Moledina, Horst Olschewski, Andrew J. Peacock, G.D. Puri, Farbod N. Rahaghi, Michal Schafer, Mark Schiebler, Nicholas Screaton, Merryn Tawhai, Edwin J.R. van Beek, Anton Vonk-Noordegraaf, Rebecca Vandepool, Stephen J. Wort, Lan Zhao, Jim M. Wild, Jens Vogel-Claussen, Andrew J. Swift
Published 2019-09-01

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

by Stefan Gräf, Matthias Haimel, Marta Bleda, Charaka Hadinnapola, Laura Southgate, Wei Li, Joshua Hodgson, Bin Liu, Richard M. Salmon, Mark Southwood, Rajiv D. Machado, Jennifer M. Martin, Carmen M. Treacy, Katherine Yates, Louise C. Daugherty, Olga Shamardina, Deborah Whitehorn, Simon Holden, Micheala Aldred, Harm J. Bogaard, Colin Church, Gerry Coghlan, Robin Condliffe, Paul A. Corris, Cesare Danesino, Mélanie Eyries, Henning Gall, Stefano Ghio, Hossein-Ardeschir Ghofrani, J. Simon R. Gibbs, Barbara Girerd, Arjan C. Houweling, Luke Howard, Marc Humbert, David G. Kiely, Gabor Kovacs, Robert V. MacKenzie Ross, Shahin Moledina, David Montani, Michael Newnham, Andrea Olschewski, Horst Olschewski, Andrew J. Peacock, Joanna Pepke-Zaba, Inga Prokopenko, Christopher J. Rhodes, Laura Scelsi, Werner Seeger, Florent Soubrier, Dan F. Stein, Jay Suntharalingam, Emilia M. Swietlik, Mark R. Toshner, David A. van Heel, Anton Vonk Noordegraaf, Quinten Waisfisz, John Wharton, Stephen J. Wort, Willem H. Ouwehand, Nicole Soranzo, Allan Lawrie, Paul D. Upton, Martin R. Wilkins, Richard C. Trembath, Nicholas W. Morrell
Published 2018-04-01