A Mouse Ependymoma Model Provides Molecular Insights into Tumor Formation

by Kristian W. Pajtler, Stefan M. Pfister
Published 2018-06-01

RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression

by Pascal David Johann, Natalie Jäger, Stefan M. Pfister, Martin Sill
Published 2019-08-01

Translating genomic medicine to the clinic: challenges and opportunities

by Huan Zhang, Lars Klareskog, Andreas Matussek, Stefan M. Pfister, Mikael Benson
Published 2019-02-01

InTAD: chromosome conformation guided analysis of enhancer target genes

by Konstantin Okonechnikov, Serap Erkek, Jan O. Korbel, Stefan M. Pfister, Lukas Chavez
Published 2019-01-01

Rapid and Sensitive Quantification of Osimertinib in Human Plasma Using a Fully Validated MALDI–IM–MS/MS Assay

by Margaux Fresnais, André Roth, Kathrin I. Foerster, Dirk Jäger, Stefan M. Pfister, Walter E. Haefeli, Jürgen Burhenne, Rémi Longuespée
Published 2020-07-01

Methylation array profiling of adult brain tumours: diagnostic outcomes in a large, single centre

by Zane Jaunmuktane, David Capper, David T. W. Jones, Daniel Schrimpf, Martin Sill, Monika Dutt, Nirosha Suraweera, Stefan M. Pfister, Andreas von Deimling, Sebastian Brandner
Published 2019-02-01

A systematic analysis of genetic interactions and their underlying biology in childhood cancer

by Josephine T. Daub, Saman Amini, Denise J. E. Kersjes, Xiaotu Ma, Natalie Jäger, Jinghui Zhang, Stefan M. Pfister, Frank C. P. Holstege, Patrick Kemmeren
Published 2021-10-01

Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells.

by Jonathan P Robson, Marc Remke, Marcel Kool, Elaine Julian, Andrey Korshunov, Stefan M Pfister, Geoffrey W Osborne, Michael D Taylor, Brandon Wainwright, Brent A Reynolds
Published 2019-01-01

Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives

by Margaux Fresnais, Esra Yildirim, Seda Karabulut, Dirk Jäger, Inka Zörnig, Julia Benzel, Kristian W. Pajtler, Stefan M. Pfister, Jürgen Burhenne, Walter E. Haefeli, Rémi Longuespée
Published 2021-02-01

From Sampling to Sequencing: A Liquid Biopsy Pre-Analytic Workflow to Maximize Multi-Layer Genomic Information from a Single Tube

by Kendra K. Maass, Paulina S. Schad, Agnes M. E. Finster, Pitithat Puranachot, Fabian Rosing, Tatjana Wedig, Nathalie Schwarz, Natalie Stumpf, Stefan M. Pfister, Kristian W. Pajtler
Published 2021-06-01

Investigating the Central Nervous System Disposition of Actinomycin D: Implementation and Evaluation of Cerebral Microdialysis and Brain Tissue Measurements Supported by UPLC-MS/MS...

by Julia Benzel, Gzona Bajraktari-Sylejmani, Philipp Uhl, Abigail Davis, Sreenath Nair, Stefan M. Pfister, Walter E. Haefeli, Johanna Weiss, Jürgen Burhenne, Kristian W. Pajtler, Max Sauter
Published 2021-09-01

High-Resolution Cartography of the Transcriptome and Methylome Landscapes of Diffuse Gliomas

by Edith Willscher, Lydia Hopp, Markus Kreuz, Maria Schmidt, Siras Hakobyan, Arsen Arakelyan, Bettina Hentschel, David T. W. Jones, Stefan M. Pfister, Markus Loeffler, Henry Loeffler-Wirth, Hans Binder
Published 2021-06-01

Proteomic analysis of Medulloblastoma reveals functional biology with translational potential

by Samuel Rivero-Hinojosa, Ling San Lau, Mojca Stampar, Jerome Staal, Huizhen Zhang, Heather Gordish-Dressman, Paul A. Northcott, Stefan M. Pfister, Michael D. Taylor, Kristy J. Brown, Brian R. Rood
Published 2018-06-01

Transcriptomic and epigenetic profiling of ‘diffuse midline gliomas, H3 K27M-mutant’ discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or in...

by David Castel, Cathy Philippe, Thomas Kergrohen, Martin Sill, Jane Merlevede, Emilie Barret, Stéphanie Puget, Christian Sainte-Rose, Christof M. Kramm, Chris Jones, Pascale Varlet, Stefan M. Pfister, Jacques Grill, David T. W. Jones, Marie-Anne Debily
Published 2018-11-01

TelomereHunter – in silico estimation of telomere content and composition from cancer genomes

by Lars Feuerbach, Lina Sieverling, Katharina I. Deeg, Philip Ginsbach, Barbara Hutter, Ivo Buchhalter, Paul A. Northcott, Sadaf S. Mughal, Priya Chudasama, Hanno Glimm, Claudia Scholl, Peter Lichter, Stefan Fröhling, Stefan M. Pfister, David T. W. Jones, Karsten Rippe, Benedikt Brors
Published 2019-05-01

Epigenetic Silencing of DKK3 in Medulloblastoma

by André Oberthuer, Giuseppe Cinalli, Tiziana Servidei, Massimo Zollo, Thomas Hielscher, Massimo Romani, Claudio Brigati, Alfa H.C. Bai, Marc Remke, Marcel Kool, Stefano Moretti, Stefan M. Pfister, Sara Stigliani, Barbara Banelli, Francesca Valdora, Gian Paolo Tonini, Simona Coco
Published 2013-04-01

Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation

by Andrey Korshunov, Konstantin Okonechnikov, Felix Schmitt-Hoffner, Marina Ryzhova, Felix Sahm, Damian Stichel, Daniel Schrimpf, David E. Reuss, Philipp Sievers, Abigail Kora Suwala, Ella Kumirova, Olga Zheludkova, Andrey Golanov, David T. W. Jones, Stefan M. Pfister, Marcel Kool, Andreas von Deimling
Published 2021-02-01

EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors

by Nevenka Dudvarski Stanković, Frank Bicker, Stefanie Keller, David TW Jones, Patrick N Harter, Arne Kienzle, Clarissa Gillmann, Philipp Arnold, Anna Golebiewska, Olivier Keunen, Alf Giese, Andreas vonDeimling, Tobias Bäuerle, Simone P Niclou, Michel Mittelbronn, Weilan Ye, Stefan M Pfister, Mirko HH Schmidt
Published 2018-09-01

Downregulation of miR‐326 and its host gene β‐arrestin1 induces pro‐survival activity of E2F1 and promotes medulloblastoma growth

by Evelina Miele, Agnese Po, Angela Mastronuzzi, Andrea Carai, Zein Mersini Besharat, Natalia Pediconi, Luana Abballe, Giuseppina Catanzaro, Claudia Sabato, Enrico De Smaele, Gianluca Canettieri, Lucia Di Marcotullio, Alessandra Vacca, Antonello Mai, Massimo Levrero, Stefan M. Pfister, Marcel Kool, Felice Giangaspero, Franco Locatelli, Elisabetta Ferretti
Published 2021-02-01

Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma

by Seçkin Akgül, Yinghua Li, Siyuan Zheng, Marcel Kool, Daniel M. Treisman, Chaoyang Li, Yuan Wang, Susanne Gröbner, Tsuneo Ikenoue, Yiping Shen, Sandra Camelo-Piragua, Gerald Tomasek, Sebastian Stark, Vinay Guduguntla, James F. Gusella, Kun-Liang Guan, Stefan M. Pfister, Roel G.W. Verhaak, Yuan Zhu
Published 2018-07-01