A Radical Role for TOR in Longevity

by Lamming, Dudley W, Sabatini, David M, Sabatini, David
Published 2014

SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway

by Harper, J. Wade, Gygi, Steven P., Gu, Xin, Orozco Segrera, Jose, Saxton, Robert Andrew, Condon, Kendall Janine, Liu, Grace Yun, Krawczyk, Patrycja A., Scaria, Sonia M., Sabatini, David
Published 2019

Global Transcriptional and Translational Repression in Human-Embryonic-Stem-Cell-Derived Rett Syndrome Neurons

by Li, Yun, Wang, Haoyi, Muffat, Julien, Cheng, Albert W, Orlando, David A., Feldman, Danielle A, Bateup, Helen S, Gao, Qing, Hockemeyer, Dirk, Mitalipova, Maisam, Lewis, Caroline A, Sur, Mriganka, Young, Richard A, Jaenisch, Rudolf, Loven, Jakob, Vander Heiden, Matthew G., Feldman, Danielle A., Young, Richard A., Lewis, Caroline, Kwok, Show Ming
Published 2016

The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1

by Chantranupong, Lynne, Orozco, Jose M, Scaria, Sonia M, Bar-Peled, Liron, Spooner, Eric, Isasa, Marta, Gygi, Steven P., Sabatini, David M, Wolfson, Rachel Laura, Saxton, Robert Andrew, Scaria, Sonia M., Sabatini, David
Published 2015

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint

by Yaffe, Michael B., Brummelkamp, Thijn R., Reinhardt, Hans, Ostheimer, Gerard, Gardino, Alexandra Kate, van Vugt, Marcel A. T. M., Smerdon, Stephen J., Carr, Steven A., Lewis, Timothy A., Pawson, Tony, Li, Jeijin, Keezer, Susan M., Miao, Hua, Tan, Chris S., Ong, Shao-En, Linding, Rune
Published 2010

mTOR and cancer: many loops in one pathway

by Efeyan, Alejo, Sabatini, David
Published 2012

A Central Role for mTOR in Lipid Homeostasis

by Lamming, Dudley W, Sabatini, David M, Lamming, Dudley W., Sabatini, David
Published 2016

Nutrient-Sensing Mechanisms across Evolution

by Chantranupong, Lynne, Wolfson, Rachel Laura, Sabatini, David
Published 2016

Viral Packaging and Cell Culture for CRISPR-Based Screens

by Wang, Tim, Lander, Eric Steven, Sabatini, David
Published 2016

Growth of human breast tissues from patient cells in 3D hydrogel scaffolds

by Breggia, Anne, Arendt, Lisa M., Sokol, Ethan Samuel, Miller, Daniel Handel, Gupta, Piyush, Spencer, Kevin C
Published 2016

Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1

by Plovanich, M. E., Straub, C., Sabatini, B. L., Tsun, Zhi-Yang, Wang, Shuyu, Wolfson, Rachel Laura, Shen, Kuang, Wyant, Gregory Andrew, Yuan, Elizabeth D., Jones, Tony D., Chantranupong, Lynne, Comb, William C., Wang, Tim, Bar-Peled, Liron, Zoncu, Roberto, Kim, Choah, Park, Jiwon, Sabatini, David
Published 2015

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance

by Kami, Kenjiro, Shelton, Laura M., Ramkissoon, Shakti H., Ligon, Keith L., Snuderl, Matija, Kim, Dohoon, Fiske, Brian Prescott, Birsoy, Kivanc, Freinkman, Elizaveta, Possemato, Richard, Chudnovsky, Yakov, Chen, Walter W., Cantor, Jason R., Gui, Dan Yi, Kwon, ManJae, Kang, Seong Woo, Vander Heiden, Matthew G., Sabatini, David, Pacold, Michael Edward
Published 2017

Rag proteins regulate amino-acid-induced mTORC1 signalling

by Sancak, Yasemin, Sabatini, David
Published 2011

The TASCC of Secretion

by Zoncu, Roberto, Sabatini, David
Published 2013

An emerging role of mTOR in lipid biosynthesis

by Laplante, Mathieu, Sabatini, David
Published 2012

mTOR Signaling in Growth Control and Disease

by Laplante, Mathieu, Sabatini, David M, Sabatini, David
Published 2014

Defective Regulation of Autophagy upon Leucine Deprivation Reveals a Targetable Liability of Human Melanoma Cells In Vitro and In Vivo

by Sheen, Joon-Ho, Zoncu, Roberto, Kim, Dohoon, Sabatini, David M, Sabatini, David
Published 2014

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

by Sengupta, Shomit, Peterson, Timothy Richard, Sabatini, David
Published 2015

Large-Scale Single Guide RNA Library Construction and Use for CRISPR-Cas9-Based Genetic Screens

by Wang, Tim, Lander, Eric Steven, Sabatini, David
Published 2016

Cancer Cell Metabolism: One Hallmark, Many Faces

by Cantor, Jason R., Sabatini, David
Published 2015