Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

by Jiang, Guozhi, Tao, Kai, Kuperwasser, Charlotte, Gupta, Piyush, Onder, Tamer T, Weinberg, Robert A, Lander, Eric Steven
Published 2015

The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy

by Scherz-Shouval, Ruth, Santagata, Sandro, Mendillo, Marc L, Sholl, Lynette M, Ben-Aharon, Irit, Beck, Andrew H, Dias-Santagata, Dora, Stemmer, Salomon M, Whitesell, Luke, Koeva, Martina I, Lindquist, Susan
Published 2016

The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

by Unternaehrer, Juli J, Zhao, Rui, Kim, Kitai, Cesana, Marcella, Powers, John T, Ratanasirintrawoot, Sutheera, Onder, Tamer T., Shibue, Tsukasa, Weinberg, Robert A, Daley, George Q., Weinberg, Robert A
Published 2015

Precision Delivery of Multiscale Payloads to Tissue‐Specific Targets in Plants

by Cao, Yunteng, Lim, Eugene J., Xu, Menglong, Weng, Jing-Ke, Marelli, Benedetto
Published 2020

Growth signaling at the nexus of stem cell life and death

by Wood, Kris C., Sabatini, David
Published 2009

Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase

by Liu, Dan, Vleugel, Mathijs, Backer, Chelsea B., Hori, Tetsuya, Fukagawa, Tatsuo, Lampson, Michael A., Cheeseman, Iain M
Published 2011

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

by Loven, Jakob, Hoke, Heather Ashley, Lin, Charles Y., Lau, Ashley, Orlando, David A., Vakoc, Christopher R., Bradner, James E., Lee, Tong Ihn, Young, Richard A.
Published 2014

Enhanced phosphocholine metabolism is essential for terminal erythropoiesis

by Huang, Nai-Jia, Lin, Chung-Yueh, Pishesha, Novalia, Lewis, Caroline A., Freinkman, Elizaveta, Lodish, Harvey
Published 2020

Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores

by Schmidt, Jens Christopher, Kiyomitsu, Tomomi, Hori, Tetsuya, Backer, Chelsea B., Fukagawa, Tatsuo, Cheeseman, Iain M
Published 2014

Widespread Regulation of Translation by Elongation Pausing in Heat Shock

by Shalgi, Reut, Hurt, Jessica A., Krykbaeva, Irina, Taipale, Mikko, Lindquist, Susan, Burge, Christopher B
Published 2015

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation

by Kaufman, C. K., Mosimann, C., Yang, S., Thomas, A. J., Ablain, J., Tan, J. L., Fogley, R. D., van Rooijen, E., Hagedorn, E. J., Ciarlo, C., White, R. M., Matos, D. A., Puller, A.-C, Santoriello, C., Liao, E. C., Zon, L. I., Fan, Zi Peng, Young, Richard A.
Published 2016

Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts

by Kim, Jongpil, Su, Susan C, Wang, Haoyi, Cheng, Albert W., Cassady, John P., Lodato, Michael Anthony, Lengner, Christopher J., Chung, Chee Yeun, Dawlaty, Meelad M., Tsai, Li-Huei, Jaenisch, Rudolf
Published 2014

Widespread Inhibition of Posttranscriptional Splicing Shapes the Cellular Transcriptome following Heat Shock

by Shalgi, Reut, Hurt, Jessica A., Lindquist, Susan, Burge, Christopher B
Published 2015

Transcriptional divergence and conservation of human and mouse erythropoiesis

by Pishesha, Novalia, Prathapan, Thiru, Jiahai, Shi, Eng, Jennifer Christina, Sankaran, Vijay G., Lodish, Harvey F
Published 2014

Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes

by Shi, Jiahai, Kundrat, Lenka, Pishesha, Novalia, Bilate, Angelina M., Theile, Christopher S., Maruyama, Takeshi, Dougan, Stephanie K., Ploegh, Hidde, Lodish, Harvey F.
Published 2015

Site-Specific Chemoenzymatic Labeling of Aerolysin Enables the Identification of New Aerolysin Receptors

by Wuethrich, Irene, Peeters, Janneke G. C., Blom, Annet E. M., Theile, Christopher S., Li, Zeyang, Spooner, Eric, Ploegh, Hidde, Guimaraes, Carla P.
Published 2014

Microfluidic high-throughput culturing of single cells for selection based on extracellular metabolite production or consumption

by Ghaderi, Adel, Zhou, Hang, Agresti, Jeremy, Stephanopoulos, Gregory, Wang, Benjamin L., Weitz, David A., Fink, Gerald R
Published 2016

Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway

by Xu, Cong, Fan, Zi Peng, Fogley, Rachel, DiBiase, Anthony, Trompouki, Eirini, Unternaehrer, Juli, Xiong, Fengzhu, Torregroza, Ingrid, Evans, Todd, Megason, Sean G, Daley, George Q., Schier, Alexander F, Young, Richard A, Zon, Leonard I, Muller, Patrick, Young, Richard A.
Published 2014

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

by Carpenter, Anne E., Jones, Thouis R., Lamprecht, Michael R., Clarke, Colin, Kang, In Han, Friman, Ola, Guertin, David A., Chang, Joo Han, Lindquist, Robert A., Moffat, Jason, Golland, Polina, Sabatini, David
Published 2010

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

by Saadatpour, Assieh, Hong, Sue-Jean, Pinello, Luca, Katz, Yarden, Lamming, Dudley W., Guo, Guoji, Bell, George W., Selig, Martin, Nielsen, G. Petur, Gupta, Nitin, Ferrone, Cristina R., Deshpande, Vikram, Yuan, Guo-Cheng, Orkin, Stuart H., Beyaz, Semir, Mana, Miyeko, Roper, Jatin, Kedrin, Dmitriy, Bauer-Rowe, Khristian E., Xifaras, Michael, Akkad, Adam, Arias, Erika, Shinagare, Shweta, Abu-Remaileh, Monther, Dogum, Rizkullah, Sabatini, David, Yilmaz, Omer, Mihaylova, Maria M.
Published 2017