An insertion variant of MGMT disrupts a STAT1 binding site and confers susceptibility to glioma

by Liming Huang, Wenshen Xu, Danfang Yan, Xi Shi, Xin You, Jiaqi Xu, Pingping You, Yuanyuan Ke, Lian Dai
Published 2021-09-01

The genetic architecture of gene expression levels in wild baboons

by Jenny Tung, Xiang Zhou, Susan C Alberts, Matthew Stephens, Yoav Gilad
Published 2015-02-01

Transcriptome-wide association study and eQTL analysis to assess the genetic basis of bulb-yield traits in garlic (Allium sativum)

by Siyuan Zhu, Xiaojun Chen, Xia Liu, Jian Zhao, Touming Liu
Published 2019-08-01

Expression Quantitative Trait Locus Mapping in Pulmonary Arterial Hypertension

by Anna Ulrich, Pablo Otero-Núñez, John Wharton, Emilia M. Swietlik, Stefan Gräf, Nicholas W. Morrell, Dennis Wang, Allan Lawrie, Martin R. Wilkins, Inga Prokopenko, Christopher J. Rhodes, on behalf of The NIHR BioResource—Rare Diseases Consortium, UK PAH Cohort Study Consortium
Published 2020-10-01

Genome-Wide Expression Quantitative Trait Loci Analysis Using Mixed Models

by Chaeyoung Lee
Published 2018-08-01

Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders

by Ling Z. Morgan, Brandi Rollins, Adolfo Sequeira, William Byerley, Lynn E. DeLisi, Alan F. Schatzberg, Jack D. Barchas, Richard M. Myers, Stanley J. Watson, Huda Akil, William E. Bunney, Marquis P. Vawter
Published 2016-03-01

Genetic Susceptibility for Low Testosterone in Men and Its Implications in Biology and Screening: Data from the UK Biobank

by Richard J. Fantus, Rong Na, Jun Wei, Zhuqing Shi, W. Kyle Resurreccion, Joshua A. Halpern, Omar Franco, Simon W. Hayward, William B. Isaacs, S. Lilly Zheng, Jianfeng Xu, Brian T. Helfand
Published 2021-07-01

Genomic structural variations lead to dysregulation of important coding and non‐coding RNA species in dilated cardiomyopathy

by Jan Haas, Stefan Mester, Alan Lai, Karen S Frese, Farbod Sedaghat‐Hamedani, Elham Kayvanpour, Tobias Rausch, Rouven Nietsch, Jes‐Niels Boeckel, Avisha Carstensen, Mirko Völkers, Carsten Dietrich, Dietmar Pils, Ali Amr, Daniel B Holzer, Diana Martins Bordalo, Daniel Oehler, Tanja Weis, Derliz Mereles, Sebastian Buss, Eva Riechert, Emil Wirsz, Maximilian Wuerstle, Jan O Korbel, Andreas Keller, Hugo A Katus, Andreas E Posch, Benjamin Meder
Published 2018-01-01

Estimating colocalization probability from limited summary statistics

by Emily A. King, Fengjiao Dunbar, Justin Wade Davis, Jacob F. Degner
Published 2021-05-01

Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease

by Adriaan van der Graaf, Maria M. Zorro, Annique Claringbould, Urmo Võsa, Urmo Võsa, Raúl Aguirre-Gamboa, Chan Li, Chan Li, Joram Mooiweer, Isis Ricaño-Ponce, Zuzanna Borek, Zuzanna Borek, Frits Koning, Yvonne Kooy-Winkelaar, Ludvig M. Sollid, Shuo-Wang Qiao, Vinod Kumar, Vinod Kumar, Yang Li, Yang Li, Yang Li, Lude Franke, Sebo Withoff, Cisca Wijmenga, Cisca Wijmenga, Serena Sanna, Serena Sanna, Iris Jonkers, Iris Jonkers, BIOS Consortium
Published 2021-01-01

Integrative Analysis of Omics Data Reveals Regulatory Network of CDK10 in Vitiligo Risk

by Minglong Cai, Minglong Cai, Tao Yuan, Tao Yuan, He Huang, He Huang, Lan Gui, Lan Gui, Li Zhang, Li Zhang, Ziyuan Meng, Ziyuan Meng, Wenjuan Wu, Wenjuan Wu, Yujun Sheng, Yujun Sheng, Xuejun Zhang, Xuejun Zhang
Published 2021-02-01

Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines

by Elizabeth Theusch, Yii-Der I. Chen, Jerome I. Rotter, Ronald M. Krauss, Marisa W. Medina
Published 2020-08-01

Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity

by Paul Geeleher, Aritro Nath, Fan Wang, Zhenyu Zhang, Alvaro N. Barbeira, Jessica Fessler, Robert L. Grossman, Cathal Seoighe, R. Stephanie Huang
Published 2018-09-01

Interchromosomal Transfer of Immune Regulation During Infection of Barley with the Powdery Mildew Pathogen

by Priyanka Surana, Ruo Xu, Gregory Fuerst, Antony V. E. Chapman, Dan Nettleton, Roger P. Wise
Published 2017-10-01

Stress, Cortisol and NR3C1 in At-Risk Individuals for Psychosis: A Mendelian Randomization Study

by Anton Iftimovici, Anton Iftimovici, Oussama Kebir, Oussama Kebir, Qin He, Thérèse M. Jay, ICAAR Study Group, Guy A. Rouleau, Marie-Odile Krebs, Marie-Odile Krebs, Boris Chaumette, Boris Chaumette, Boris Chaumette, Isabelle Amado, Julie Bourgin, Claire Daban Huard, Célia Jantac Mam-Lam-Fook, Marion Plaze, Fabrice Rivollier
Published 2020-07-01

The Integrated Landscape of Biological Candidate Causal Genes in Coronary Artery Disease

by Qiwen Zheng, Yujia Ma, Si Chen, Qianzi Che, Dafang Chen
Published 2020-04-01

Transcribing β-cell mitochondria in health and disease

by Hindrik Mulder
Published 2017-09-01

Bayesian Inference for Mixed Model-Based Genome-Wide Analysis of Expression Quantitative Trait Loci by Gibbs Sampling

by Chaeyoung Lee
Published 2019-03-01

PHACTR1 splicing isoforms and eQTLs in atherosclerosis-relevant human cells

by Valérie-Anne Codina-Fauteux, Mélissa Beaudoin, Simon Lalonde, Ken Sin Lo, Guillaume Lettre
Published 2018-06-01

rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology

by Linda E. Kelemen, Madalene Earp, Brooke L. Fridley, Georgia Chenevix-Trench, on behalf of Australian Ovarian Cancer Study Group, Peter A. Fasching, Matthias W. Beckmann, Arif B. Ekici, Alexander Hein, Diether Lambrechts, Sandrina Lambrechts, Els Van Nieuwenhuysen, Ignace Vergote, Mary Anne Rossing, Jennifer A. Doherty, Jenny Chang-Claude, Sabine Behrens, Kirsten B. Moysich, Rikki Cannioto, Shashikant Lele, Kunle Odunsi, Marc T. Goodman, Yurii B. Shvetsov, Pamela J. Thompson, Lynne R. Wilkens, Thilo Dörk, Natalia Antonenkova, Natalia Bogdanova, Peter Hillemanns, Ingo B. Runnebaum, Andreas du Bois, Philipp Harter, Florian Heitz, Ira Schwaab, Ralf Butzow, Liisa M. Pelttari, Heli Nevanlinna, Francesmary Modugno, Robert P. Edwards, Joseph L. Kelley, Roberta B. Ness, Beth Y. Karlan, Jenny Lester, Sandra Orsulic, Christine Walsh, Susanne K. Kjaer, Allan Jensen, Julie M. Cunningham, Robert A. Vierkant, Graham G. Giles, Fiona Bruinsma, Melissa C. Southey, Michelle A.T. Hildebrandt, Dong Liang, Karen Lu, Xifeng Wu, Thomas A. Sellers, Douglas A. Levine, Joellen M. Schildkraut, Edwin S. Iversen, Kathryn L. Terry, Daniel W. Cramer, Shelley S. Tworoger, Elizabeth M. Poole, Elisa V. Bandera, Sara H. Olson, Irene Orlow, Liv Cecilie Vestrheim Thomsen, Line Bjorge, Camilla Krakstad, Ingvild L. Tangen, Lambertus A. Kiemeney, Katja K.H. Aben, Leon F.A.G. Massuger, Anne M. van Altena, Tanja Pejovic, Yukie Bean, Melissa Kellar, Linda S. Cook, Nhu D. Le, Angela Brooks-Wilson, Jacek Gronwald, Cezary Cybulski, Anna Jakubowska, Jan Lubiński, Nicolas Wentzensen, Louise A. Brinton, Jolanta Lissowska, Estrid Hogdall, Svend Aage Engelholm, Claus Hogdall, Lene Lundvall, Lotte Nedergaard, Paul D.P. Pharoah, Ed Dicks, Honglin Song, Jonathan P. Tyrer, Iain McNeish, Nadeem Siddiqui, Karen Carty, Rosalind Glasspool, James Paul, Ian G. Campbell, Diana Eccles, Alice S. Whittemore, Valerie McGuire, Joseph H. Rothstein, Weiva Sieh, Steven A. Narod, Catherine M. Phelan, John R. McLaughlin, Harvey A. Risch, Hoda Anton-Culver, Argyrios Ziogas, Usha Menon, Simon A. Gayther, Aleksandra Gentry-Maharaj, Susan J. Ramus, Anna H. Wu, Celeste Leigh Pearce, Alice W. Lee, Malcolm C. Pike, Jolanta Kupryjanczyk, Agnieszka Podgorska, Joanna Plisiecka-Halasa, Wlodzimierz Sawicki, Ellen L. Goode, Andrew Berchuck, Ovarian Cancer Association Consortium
Published 2018-08-01